Protein Alignment Glt and nlgn4xb

DIOPT Version :10

• Sequence 1: NP_477504.1
• Gene: Glt / 34193
• FlyBaseID: FBgn0001114
• Length: 1026
• Species: Drosophila melanogaster
• Sequence 2: NP_001159809.1
• Gene: nlgn4xb / 100147967
• ZFINID: ZDB-GENE-100309-1
• Length: 795
• Species: Danio rerio
• Alignment Length: 767
• Identity: 192/767 - (25%)
• Similarity: 295/767 - (38%)
• Gaps: 205/767 - (26%)

  Fly    52 TRYAQPQEAVVQAPEVGQILGISGHKTIANRPVNAFLGIRYGTVGGGLARFQAAQ-PIGYQGRVN 115
            |.|.:.:...|..|  .:|||          ||..|||:.|.....|..||||.: |:.:.|..|
Zfish    27 TNYGKLRGLRVALP--SEILG----------PVEQFLGVPYAMAPTGERRFQAPEPPLSWPGIRN 79

  Fly   116 ATVQSPNCAQFPELDRLRLSESR----GENVD-----------DCLTLDIYAP------EGANQL 159
            ||..:|.|.||.| |||.|::..    ..|:|           |||.|:||.|      :.|...
Zfish    80 ATQFAPVCPQFLE-DRLLLTDMLPVWFTANLDTVATYVHDQSEDCLYLNIYVPTEEETQDDAGLK 143

  Fly   160 PVLVFVHGEMLFDG------GSEEAQPDYVLEK--DVLLVSINYRLAPFGFLSALTDELPGNVAL 216
            ||:|::||....:|      ||       ||..  :|::|::||||...||||.......||..|
Zfish   144 PVMVYIHGGSYVEGTGNMIDGS-------VLASYGNVIVVTVNYRLGVLGFLSTGDQAAKGNYGL 201

  Fly   217 SDLQLALEWLQRNVVHFGGNAGQVTLVGQAGGATLAHALSLSGRAGNLFQQLILQSGTALNPYLI 281
            .|...||.|::.|:..|.|:..:||:.|...||:....|:||..:.:|||:.|:.|||||:.:.:
Zfish   202 LDQIQALRWVKENIQSFSGDPERVTIFGSGAGASCVSLLTLSHYSEDLFQKAIIHSGTALSSWAV 266

  Fly   282 DNQPLDTLSTFARLARCPPPSINPSAQGLKPLYDCLARLPTSQLVAAFEQLLLQNEHLGLTQLGG 346
            :.||       |:..|.....:..:......|.:||..       ..:::|:.||.......:..
Zfish   267 NYQP-------AKYTRLLAEKVGCNEDDTLELIECLQS-------KNYKELIEQNITPAKYHIAF 317

  Fly   347 FKLVVGDPLGFLPSHPASLATNSS-LALPMIIGATKDASAFIVSRIYDQLARLQSRN----VSDY 406
            ..::.||   .:|..|..|..... |...:::|..:......|..|.|...|:.|.:    :|::
Zfish   318 GPVIDGD---VIPDDPQILMEQGEFLNYDIMLGVNQGEGYKFVDGILDSEDRVTSNDFEFAISEF 379

  Fly   407 IDVV---------LRHTAPPSEHRLWKQWALRE-----------IFTPIQEQTASLQTVAPGLLE 451
            :|.:         ||.|.    ..::..||.||           :||       ..|.|||.:..
Zfish   380 VDHLYGYPEGKDTLRETI----KFMYTDWADRENPEMRRKTLVALFT-------DHQWVAPAVAT 433

  Fly   452 LSNYILYRAPVINSISQSYRSVPAYLYTFDYRGEHHRFGHLSNPLPFGVDASLSDDSVYLFPYPP 516
            ...:..|.:             |.|.|.|    .||   ..|:..|...|:|..|:..|:|..|
Zfish   434 ADLHAQYGS-------------PTYFYAF----YHH---CQSDMKPAWADSSHGDELPYVFGIP- 477

  Fly   517 EASRLNPLDR----------SLSRALVTMWVNFATTGVPNPSSGVWPQAT--------------- 556
               .:.|.|.          .||..::|.|.|||.||.||...   ||.|
Zfish   478 ---MIGPTDLFNCNFSKNDIMLSAVVMTYWTNFAKTGDPNQPV---PQDTKFIHTKPNRFEEVAW 536

  Fly   557 SEYGP----FL------RFTNNQQSP-----LELDPHFGEGIYLPNYRVIYKPTTNFSPPITTTT 606
            |:|.|    :|      |..::.::.     |||.||    ::..|....|..:|...||..||.
Zfish   537 SKYNPKDQLYLHIGLKPRVRDHYRATKIAFWLELVPH----LHNINELFQYVSSTTKIPPQDTTP 597

  Fly   607 TTTTT-------TTTTSRPYAYNPYANWQNRPSQQHPNWHPADPEYVRAQEARQQ---------- 654
            .:.|.       .:||..|.|  |.||.:....||..:.|......:.|::...:
Zfish   598 FSYTKRLSNKLFPSTTRHPPA--PPANTKQMSDQQKTSEHADGTVIIEARDYSTELSVTIAVGAS 660

  Fly   655 ------------EFIREREQRRREQQLRDQQRYPQQEPREQQDERIRQQREQ 694
                        .:.:::.:....::|...:.:....||...:|.:..|.:|
Zfish   661 LLFLNILAFAALYYKKDKHRLESSRRLSPPRNHANDIPRVPSEELMSLQMKQ 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_477504.1	COesterase	58..579	CDD:395084	164/615 (27%)
		Casc1_N	681..>717	CDD:464947	4/14 (29%)
nlgn4xb	NP_001159809.1	COesterase	24..567	CDD:395084	162/614 (26%)