Protein Alignment Glt and nlgn1

DIOPT Version :9

• Sequence 1: NP_001245946.1
• Gene: Glt / 34193
• FlyBaseID: FBgn0001114
• Length: 1026
• Species: Drosophila melanogaster
• Sequence 2: XP_017213657.1
• Gene: nlgn1 / 100002610
• ZFINID: ZDB-GENE-090918-1
• Length: 867
• Species: Danio rerio
• Alignment Length: 927
• Identity: 209/927 - (22%)
• Similarity: 306/927 - (33%)
• Gaps: 323/927 - (34%)

  Fly    68 GQILGISGHKTIANR---PVNAFLGIRYGTVGGGLARFQAAQ-PIGYQGRVNATVQSPNCAQFPE 128
            |::.|..  |.:.|.   ||..|||:.|.....|..|||..: ||.:....|||..:|.|.|
Zfish    61 GKVRGFK--KELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPISWSEIRNATQFAPVCPQ--- 120

  Fly   129 LDRLRLSESRGENV---------------------DDCLTLDIYAP------------------- 153
                .|.|.|..:|                     :|||.|:||.|
Zfish   121 ----TLLEGRLPDVMLPVWFTNSIEVVSSYVQDQSEDCLFLNIYVPTEDVKRISKECARKPGKKI 181

  Fly   154 ---------------------------EGANQLPVLVFVHGEM-------LFDGGSEEAQPDYVL 184
                                       |..:..||:|||||..       :|||.        :|
Zfish   182 CRKGGPLSKKQNDDLADNDGAEDEDIRESGSPKPVMVFVHGGSYMEGTGNMFDGS--------IL 238

  Fly   185 EK--DVLLVSINYRLAPFGFLSALTDELPGNVALSDLQLALEWLQRNVVHFGGNAGQVTLVGQAG 247
            ..  :|:::::||||...||||.......||..|.||..||.|...|:..|||:..::|:.|...
Zfish   239 ASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIAFFGGDPLRITVFGSGA 303

  Fly   248 GATLAHALSLSGRA-GN--------LFQQLILQSGTALNPYLIDNQPLDTLSTFARLARCPPPSI 303
            ||:..:.|:||..: ||        |||:.|.||||||:.:.:..||       |:.||.....:
Zfish   304 GASCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQP-------AKYARMLAKKV 361

  Fly   304 NPSAQGLKPLYDCLARLPTSQLVAAFEQLLLQNEHLGLTQLGGFKLVVGDPLGFLPSHPASLATN 368
            ..:.:....:.:||.:....:||.  :.:.....|:...     .::.||   .:|..|..|...
Zfish   362 GCNLKDTVEMVECLQKKHYKELVE--QDIQPARYHIAFG-----PVIDGD---VIPDDPQILMEQ 416

  Fly   369 SS-LALPMIIGATKDASAFIVSRIYDQLARLQSRN----VSDYID---------VVLRHTAPPSE 419
            .. |...:::|..:......|..|.|....:|:.:    ||.::|         .:||.|.
Zfish   417 GEFLNYDIMLGVNQGEGLKFVELIVDNENGVQANDFDYAVSSFVDDLYGYPEGKDILRETI---- 477

  Fly   420 HRLWKQWALREIFTPIQEQTASLQTVAPGLLELSNYILYRAPVINS--ISQSYRSVPAYLYTFDY 482
            ..::..||.|.          :.:|....||.|.....:.||.:.:  :..|:.| |.|.|.|
Zfish   478 KFMYTDWADRH----------NPETRRKTLLALFTDHQWVAPAVATADLHSSFGS-PTYFYAF-- 529

  Fly   483 RGEHHRFGHLSNPLPFGVDASLSDDSVYLFPYP---PEASRLNPL-----DRSLSRALVTMWVNF 539
              .||   ..:..:|...||:..|:..|:|..|   |  :.|.|.     |..||..::|.|.||
Zfish   530 --YHH---CQTEQVPPWADAAHGDEIPYVFGLPMIGP--TELFPCNFSKNDVMLSAVVMTYWTNF 587

  Fly   540 ATTGVPNPSSGVWPQATS---------EYGPFLRFTNNQQ-------SP--------------LE 574
            |.||.||...   ||.|.         |...:.|:....|       .|              ||
Zfish   588 AKTGDPNQPV---PQDTKFIHTKPNRFEEVAWTRYNQKDQLYLHIGLKPRVKEHYRANKVNLWLE 649

  Fly   575 LDPHFGEGIYLPNYRVIYKPTTNFSPPITTTTTTTTTTTTTSRPYAYNPYANWQNRPSQQHPNWH 639
            |.||    ::..|.......||...||..|..|.......|.||
Zfish   650 LVPH----LHSLNEVSQIISTTKLPPPEVTPRTPKKIPVNTKRP--------------------- 689

  Fly   640 PADPEYVRAQEARQQEFIREREQRRREQQLRDQQRYPQQEPREQQDERIRQQREQEERLRQQREQ 704
                                               ||...|.|.||.  ..|.:.:..|..||:.
Zfish   690 -----------------------------------YPTPFPTETQDS--HNQNQNQPFLVDQRDY 717

  Fly   705 EERL--------------------------RQQRELEERIRQQQEREQYEREQQERE----QRER 739
            ...|                          :::.|:..|...|:.........||.|    |.:.
Zfish   718 STELSVTIAVGASLLFLNILAFAALYYKKDKRRHEVHRRCSPQRTTANELPHTQEEEIMSLQMKH 782

  Fly   740 EELERQQREREQQQPEQ-------QPEY------NPEPVNPWGYPVQEPQ-----PDDNPEDGRL 786
            .:|||:.  ||...|.:       .|:|      :|:.:     |:..|.     |:..|  |..
Zfish   783 SDLEREC--REAMHPHEVVLRTACPPDYTLAMRRSPDDI-----PLMTPNTITMIPNSMP--GLT 838

  Fly   787 PYPSYEQYGPEGNENLP 803
            ....:..|....|..||
Zfish   839 SLHPFNSYSSGQNNTLP 855

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_001245946.1	COesterase	55..579	CDD:278561	162/653 (25%)
		Aes	<146..345	CDD:223730	67/262 (26%)
		RILP-like	<677..>717	CDD:304877	10/65 (15%)
nlgn1	XP_017213657.1	COesterase	53..647	CDD:306613	158/646 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575475
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930