Protein Alignment Glt and nlgn1

DIOPT Version :10

• Sequence 1: NP_477504.1
• Gene: Glt / 34193
• FlyBaseID: FBgn0001114
• Length: 1026
• Species: Drosophila melanogaster
• Sequence 2: XP_017213657.1
• Gene: nlgn1 / 100002610
• ZFINID: ZDB-GENE-090918-1
• Length: 867
• Species: Danio rerio
• Alignment Length: 927
• Identity: 209/927 - (22%)
• Similarity: 306/927 - (33%)
• Gaps: 323/927 - (34%)

  Fly    68 GQILGISGHKTIANR---PVNAFLGIRYGTVGGGLARFQAAQ-PIGYQGRVNATVQSPNCAQFPE 128
            |::.|..  |.:.|.   ||..|||:.|.....|..|||..: ||.:....|||..:|.|.|
Zfish    61 GKVRGFK--KELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPISWSEIRNATQFAPVCPQ--- 120

  Fly   129 LDRLRLSESRGENV---------------------DDCLTLDIYAP------------------- 153
                .|.|.|..:|                     :|||.|:||.|
Zfish   121 ----TLLEGRLPDVMLPVWFTNSIEVVSSYVQDQSEDCLFLNIYVPTEDVKRISKECARKPGKKI 181

  Fly   154 ---------------------------EGANQLPVLVFVHGEM-------LFDGGSEEAQPDYVL 184
                                       |..:..||:|||||..       :|||.        :|
Zfish   182 CRKGGPLSKKQNDDLADNDGAEDEDIRESGSPKPVMVFVHGGSYMEGTGNMFDGS--------IL 238

  Fly   185 EK--DVLLVSINYRLAPFGFLSALTDELPGNVALSDLQLALEWLQRNVVHFGGNAGQVTLVGQAG 247
            ..  :|:::::||||...||||.......||..|.||..||.|...|:..|||:..::|:.|...
Zfish   239 ASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIAFFGGDPLRITVFGSGA 303

  Fly   248 GATLAHALSLSGRA-GN--------LFQQLILQSGTALNPYLIDNQPLDTLSTFARLARCPPPSI 303
            ||:..:.|:||..: ||        |||:.|.||||||:.:.:..||       |:.||.....:
Zfish   304 GASCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQP-------AKYARMLAKKV 361

  Fly   304 NPSAQGLKPLYDCLARLPTSQLVAAFEQLLLQNEHLGLTQLGGFKLVVGDPLGFLPSHPASLATN 368
            ..:.:....:.:||.:....:||.  :.:.....|:...     .::.||   .:|..|..|...
Zfish   362 GCNLKDTVEMVECLQKKHYKELVE--QDIQPARYHIAFG-----PVIDGD---VIPDDPQILMEQ 416

  Fly   369 SS-LALPMIIGATKDASAFIVSRIYDQLARLQSRN----VSDYID---------VVLRHTAPPSE 419
            .. |...:::|..:......|..|.|....:|:.:    ||.::|         .:||.|.
Zfish   417 GEFLNYDIMLGVNQGEGLKFVELIVDNENGVQANDFDYAVSSFVDDLYGYPEGKDILRETI---- 477

  Fly   420 HRLWKQWALREIFTPIQEQTASLQTVAPGLLELSNYILYRAPVINS--ISQSYRSVPAYLYTFDY 482
            ..::..||.|.          :.:|....||.|.....:.||.:.:  :..|:.| |.|.|.|
Zfish   478 KFMYTDWADRH----------NPETRRKTLLALFTDHQWVAPAVATADLHSSFGS-PTYFYAF-- 529

  Fly   483 RGEHHRFGHLSNPLPFGVDASLSDDSVYLFPYP---PEASRLNPL-----DRSLSRALVTMWVNF 539
              .||   ..:..:|...||:..|:..|:|..|   |  :.|.|.     |..||..::|.|.||
Zfish   530 --YHH---CQTEQVPPWADAAHGDEIPYVFGLPMIGP--TELFPCNFSKNDVMLSAVVMTYWTNF 587

  Fly   540 ATTGVPNPSSGVWPQATS---------EYGPFLRFTNNQQ-------SP--------------LE 574
            |.||.||...   ||.|.         |...:.|:....|       .|              ||
Zfish   588 AKTGDPNQPV---PQDTKFIHTKPNRFEEVAWTRYNQKDQLYLHIGLKPRVKEHYRANKVNLWLE 649

  Fly   575 LDPHFGEGIYLPNYRVIYKPTTNFSPPITTTTTTTTTTTTTSRPYAYNPYANWQNRPSQQHPNWH 639
            |.||    ::..|.......||...||..|..|.......|.||
Zfish   650 LVPH----LHSLNEVSQIISTTKLPPPEVTPRTPKKIPVNTKRP--------------------- 689

  Fly   640 PADPEYVRAQEARQQEFIREREQRRREQQLRDQQRYPQQEPREQQDERIRQQREQEERLRQQREQ 704
                                               ||...|.|.||.  ..|.:.:..|..||:.
Zfish   690 -----------------------------------YPTPFPTETQDS--HNQNQNQPFLVDQRDY 717

  Fly   705 EERL--------------------------RQQRELEERIRQQQEREQYEREQQERE----QRER 739
            ...|                          :::.|:..|...|:.........||.|    |.:.
Zfish   718 STELSVTIAVGASLLFLNILAFAALYYKKDKRRHEVHRRCSPQRTTANELPHTQEEEIMSLQMKH 782

  Fly   740 EELERQQREREQQQPEQ-------QPEY------NPEPVNPWGYPVQEPQ-----PDDNPEDGRL 786
            .:|||:.  ||...|.:       .|:|      :|:.:     |:..|.     |:..|  |..
Zfish   783 SDLEREC--REAMHPHEVVLRTACPPDYTLAMRRSPDDI-----PLMTPNTITMIPNSMP--GLT 838

  Fly   787 PYPSYEQYGPEGNENLP 803
            ....:..|....|..||
Zfish   839 SLHPFNSYSSGQNNTLP 855

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_477504.1	COesterase	58..579	CDD:395084	162/653 (25%)
		Casc1_N	681..>717	CDD:464947	9/61 (15%)
nlgn1	XP_017213657.1	COesterase	53..647	CDD:395084	158/646 (24%)