Protein Alignment Sema1a and sema4bb

DIOPT Version :9

• Sequence 1: NP_001260265.1
• Gene: Sema1a / 34192
• FlyBaseID: FBgn0011259
• Length: 1131
• Species: Drosophila melanogaster
• Sequence 2: XP_005168979.2
• Gene: sema4bb / 561146
• ZFINID: ZDB-GENE-120503-1
• Length: 849
• Species: Danio rerio
• Alignment Length: 982
• Identity: 263/982 - (26%)
• Similarity: 414/982 - (42%)
• Gaps: 281/982 - (28%)

  Fly    49 WMQVFLLLTVL--VIGNQSAWQENIRPKLYVELGPE--DVLKF----VGNESVVDHFKLVTKDGN 105
            |:..:.:..||  |:.:..|.::::..::......|  .|..|    |.|.|.:    |::.|.|
Zfish    20 WLLFWSIWIVLAGVLQSTMASEDDVTARISFTYNAEGRSVSGFSVNGVYNYSAL----LLSPDEN 80

  Fly   106 SLLIGARNTVFNLSIHDLVE---QQRLVWTSPEDDTKMCLVKGKDEEA-CQNYIRIMVVPSPGRL 166
            .:.:|||..:|:||:.::..   |:.|.|::||.....|:.||||.:. |.|||:|::..:...|
Zfish    81 KIYVGARENIFSLSLDNISVTHLQKTLTWSTPETKRGECIFKGKDPQTDCFNYIKILLRLNSTHL 145

  Fly   167 FVCGTNSFRPMCNTYIISDSNYTLEATKNGQAV-------CPYDPRHNSTSVLADNELYSGTVAD 224
            |||||.:|.|:| || |:.|:::|||.:.|:.:       ||::|.:.||::..|.|||:.||::
Zfish   146 FVCGTYAFSPIC-TY-INISSFSLEADEKGEPIMEDGRGRCPFNPEYRSTAITVDGELYTATVSN 208

  Fly   225 FSGSDPIIYRE-----PLQTEQYDSLS-LNAPNFVSSF--------TQGDFVYFFFRETAVEFIN 275
            |.|::|.|||.     ||:||  :||: |..|.||.|.        ...|.:||||.||..||..
Zfish   209 FQGNEPSIYRSLGSGTPLKTE--NSLNWLQDPAFVGSAHITGSDSERNDDQIYFFFSETGKEFDF 271

  Fly   276 CGKAIYSRVARVCKWDKGGPHRFRNRWTSFLKSRLNCSIPGD-YPFYFNEIQSASNLVEGQY--- 336
            ....|.||:|||||.|:||....:.:||:|||::|.||:|.| :||         |:::..|
Zfish   272 FDNTIVSRIARVCKEDQGGERVLQKKWTTFLKAQLLCSLPDDGFPF---------NIIQDVYVLP 327

  Fly   337 -GSMSSKLIYGVFNTP-SNSIPG-SAVCAFALQDIADTFEGQFKEQTGINSNWLPVNNAKVPDPR 398
             ....:.|:|.||.:. |..:.| ||||.|::..:...|.|::||.......|.....: ||:||
Zfish   328 AKRKKNTLLYAVFASQWSKGLAGSSAVCVFSMDQVDQAFTGRYKEVNRETQQWYTYTQS-VPEPR 391

  Fly   399 PGSC-HNDSRAL--------PDPTLNFIKTHSLMDENVPAFFSQPILVRTSTIYRFTQIAVDAQI 454
            ||.| .|.||.|        ||..|||:|.|.|||..|.   |||:|. |.|:: :|||||. .:
Zfish   392 PGMCITNASRQLGIDSSLDMPDKVLNFVKDHFLMDRPVR---SQPVLF-THTVH-YTQIAVH-HV 450

  Fly   455 KTPGG--KTYDVIFVGTDHGKIIKSVNAESADSADKVTSVVIEEIDVLTKSEPIRNLEIVRTMQY 517
            |   |  :.|||:|:||..|::.|:||...       ...:||||.:.::.:|::.:|:
Zfish   451 K---GLHRAYDVMFIGTADGRLQKAVNVAG-------MMHIIEEIQLFSEQQPVQQIEL------ 499

  Fly   518 DQPKDGSYDDGKLIIVTDSQVVAIQLHRC--HNDKITSCSECVALQDPYCAWDKIAGKCRSHGAP 580
            |..|      |.|.:.:.|.:|.:.:..|  ||    :|.|||..:||||||
Zfish   500 DSAK------GLLFVSSHSGIVQLPVANCSFHN----NCGECVLARDPYCAW------------- 541

  Fly   581 RWLEENYFYQNVATGQHAACPSGKINSKDANAGEQKGFRNDMDLLDSRRQSKDQEIIDNIDKNFE 645
                         ||.|.                     .|:.|:..  |::.|:.|:..|.:
Zfish   542 -------------TGTHC---------------------TDVTLVPP--QNQWQQDIEEADTS-- 568

  Fly   646 GPQISADIINAQYTVETLVMAVLAGSIFSLLVGFFTGYFCGRRCHKDEDDNLPYPDTEYEYFEQR 710
                         ...:.::.|.:||..|                                  .|
Zfish   569 -------------KCNSTMLRVDSGSSVS----------------------------------PR 586

  Fly   711 QNVNSFPSSCRIQQEPKLLPQVEEVTYAEPVLLP----QPPPPN--KMHSPKNTLRKPPMHQMHQ 769
            ...||..|.|                  |.:::|    |..|.|  ..|:.:..|.||.:
Zfish   587 SFTNSETSDC------------------ELIIIPANTLQLLPCNLRSNHAHRKWLYKPNV----- 628

  Fly   770 GPNSETLFQFQPDGYNTQQSYRGRDNFGTLRSH-----QVMGDNYRRGDGFSTTRS--------- 820
               |..||. ..||........|.|...:..|.     |::.:...:.:..|.|.:
Zfish   629 ---SHFLFP-SADGGLVVSGRAGSDEVFSCWSEERGFWQLLANYCVKAEPLSETTTKIGRKEAPF 689

  Fly   821 -VKKAVNNTNTRNRSLGRARRQPPRHG--------------------IVTQHRSNSPQ-----QQ 859
             ::...::..:.......|:.:...:|                    :|.:||....:     :|
Zfish   690 LIQSIASDILSEESEAHSAQHRIKTYGTELAVVCVLLAVCVLSFGLSVVYRHRGRMKEVLRGGEQ 754

  Fly   860 QQQSQQPHSSSGSS-PVMSNSSSSPAPPSSSPSPQESPKNCSYIYRDXLICNTKSMPLIQAQSTH 923
            ...:|:.....|.| |:  |:.:.|..||...|.|...:|||||....    ..:.|....::..
Zfish   755 AGGAQKSTVHPGESLPL--NAGAPPTSPSEHKSYQTLEENCSYIIAPA----ETNTPQKSEETQI 813

  Fly   924 AQPHPQS 930
            .:|.||:
Zfish   814 LKPTPQN 820

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1a	NP_001260265.1	Sema_1A	91..546	CDD:200498	177/497 (36%)
		PSI	545..>579	CDD:214655	13/35 (37%)
sema4bb	XP_005168979.2	Sema_4B	61..520	CDD:200518	180/504 (36%)
		PSI	521..570	CDD:307546	22/116 (19%)
		Ig	596..670	CDD:325142	19/100 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910