Protein Alignment Sema1a and sema3c

DIOPT Version :9

• Sequence 1: NP_001260265.1
• Gene: Sema1a / 34192
• FlyBaseID: FBgn0011259
• Length: 1131
• Species: Drosophila melanogaster
• Sequence 2: XP_017210807.2
• Gene: sema3c / 553130
• ZFINID: ZDB-GENE-050513-5
• Length: 757
• Species: Danio rerio
• Alignment Length: 697
• Identity: 187/697 - (26%)
• Similarity: 334/697 - (47%)
• Gaps: 120/697 - (17%)

  Fly    50 MQVFLLLTVLVIGNQSAWQENIRPKLYVELGPEDVLK------FVGNESVVDHFKLVT-KDGNSL 107
            :|:||||.:.|....:.  .:.:|::::..  :::.|      :..:|..:|:..|.| :|.:.:
Zfish    16 VQLFLLLGLSVSSIHAL--SSPQPRVFLPF--QELQKTQSFEHYSLSEKAMDYRILFTDEDQDRM 76

  Fly   108 LIGARNTVFNLSIHDLVEQQ-RLVWTSPEDDTKMCLVKGKD-EEACQNYIRIMVVPSPGRLFVCG 170
            .:|.::.:.::.|:::.:.. ::.|.:.....:.|.:.||| ...|.|::|::...:...||:||
Zfish    77 YVGCKDHILSMDINNISQATLKIFWPASISKVEECQMAGKDPTHGCGNFLRVIQPYNRTHLFICG 141

  Fly   171 TNSFRPMC-----------NTYIISDSNYTLEATKNGQAVCPYDPRHNSTSVLADNELYSGTVAD 224
            :.::.|:|           ..:.||      ...::|:..|.::|:.|:.||:.:.||:||...|
Zfish   142 SGAYSPVCAYVNRGRRPEEQVFQIS------SRAESGKGRCSFNPQVNTVSVMLNQELFSGMYID 200

  Fly   225 FSGSDPIIY-----REPLQTEQYDSLSLNAPNFVSSFTQGD-------FVYFFFRETAVEFINCG 277
            |.|:|..|:     |.|::|:|::|..|:.|.|:.:....|       .:|||.||...:.....
Zfish   201 FMGTDAAIFRSLTTRNPVRTDQHNSKWLSEPLFIDAQLIPDGSDPNDAKLYFFLRERLTDTSGNT 265

  Fly   278 KAIYSRVARVCKWDKGGPHRFRNRWTSFLKSRLNCSI--PGDYPFYFNEIQSASNLVEGQYGSMS 340
            |.|::.|||||..|.||.....|:||:|||:|:.||:  ......:|:|:::.. |:|..:  ..
Zfish   266 KNIHAMVARVCPNDTGGQRSLVNKWTTFLKARMVCSVLEEDGTETHFDELENVF-LLETDH--PK 327

  Fly   341 SKLIYGVFNTPSNSIPGSAVCAFALQDIADTFEGQFKEQTGINSNWLPVNNAKVPDPRPGSC--- 402
            ..||:|||.:.|:...|||||.:.:.||...|.|.|..:.|.|..|:.. ..::|.||||:|
Zfish   328 GLLIFGVFTSTSSVFRGSAVCVYNMADILTVFNGPFAHREGPNFQWVAF-QGRIPYPRPGTCPGG 391

  Fly   403 ----H-NDSRALPDPTLNFIKTHSLMDENVPAFFSQPILVRTSTIYRFTQIAVDAQIKTPGGKTY 462
                | ..::..||..:.|::.|.:|...:.....:|::|||...|::|.|||| |:....|. |
Zfish   392 AFTPHIQSTKEFPDDVVTFVRNHPVMFNPIYPVGRKPLVVRTHADYKYTSIAVD-QVPAADGH-Y 454

  Fly   463 DVIFVGTDHGKIIKSVNAESADSADKVTSVVIEEIDVLTKSEPIRNLEIVRTMQYDQPKDGSYDD 527
            .|:|:|||.|.:.|.|...|..|.|:  .:::||::|.....||.||.|....|
Zfish   455 QVLFLGTDKGTVQKVVVLPSNGSLDE--DLILEELEVFKTQSPITNLRISSKKQ----------- 506

  Fly   528 GKLIIVTDSQVVAIQLHRCHNDKITSCSECVALQDPYCAWDKIA-------GKCRS------HGA 579
             :|.:.::..:..:.|||| |...::|::|...:|||||||.::       ||.||      ||.
Zfish   507 -QLYVSSEHGISQVSLHRC-NAYGSACADCCLARDPYCAWDGLSCSRFYPTGKRRSRRQDIMHGN 569

  Fly   580 PRWLEENYFYQNVATGQHAACPSGKINS-KDANAGEQKGFRNDMDLLDSRRQSKDQEI-----ID 638
            |.                ..|....:.: ::|....|.|.:|:...|:.:.:|....:     .|
Zfish   570 PL----------------TQCRGFNLKAYRNAVEMTQYGVKNNTTFLECQPKSPQASVKWLIQRD 618

  Fly   639 NIDKNFEGPQISADIINAQYTVETLVMAVLAGSIFSLLVGFFTGYFC 685
            | |:..| .::|..:::..:       .:|..|:.|...|.   |:|
Zfish   619 N-DRRKE-VKLSDRVVSTNH-------GLLIRSVHSSDQGL---YYC 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1a	NP_001260265.1	Sema_1A	91..546	CDD:200498	142/490 (29%)
		PSI	545..>579	CDD:214655	17/46 (37%)
sema3c	XP_017210807.2	Sema_3C	55..524	CDD:200512	142/494 (29%)
		PSI	523..568	CDD:214655	16/45 (36%)
		Ig_Semaphorin_classIII	585..674	CDD:143279	17/81 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010