Protein Alignment Sema1a and sema3ga

DIOPT Version :9

• Sequence 1: NP_001260265.1
• Gene: Sema1a / 34192
• FlyBaseID: FBgn0011259
• Length: 1131
• Species: Drosophila melanogaster
• Sequence 2: NP_001014823.1
• Gene: sema3ga / 544659
• ZFINID: ZDB-GENE-050513-3
• Length: 749
• Species: Danio rerio
• Alignment Length: 591
• Identity: 175/591 - (29%)
• Similarity: 278/591 - (47%)
• Gaps: 91/591 - (15%)

  Fly   100 VTKDGNSLLIGARNTVFNLSIHDLVEQQRLV-WTSPEDDTKMCLVKGKDEEA-CQNYIRIMVVPS 162
            |..|...|.:|:|..:.:|.:.::.::..:: |.:|......|.:.||.... |.|::|::...:
Zfish    64 VDPDQGRLYLGSREYLVSLDMQNINKEPLIIHWPAPAQRKGECQLTGKGRHGECANFVRLIEPWN 128

  Fly   163 PGRLFVCGTNSFRPMCNTYI-----ISDSNYTLEA--TKNGQAVCPYDPRHNSTSVLADNELYSG 220
            ...|:.|||.:::|:| |:|     ..|..:.|..  ..:|:..|.|||...:.:.|.:..||:|
Zfish   129 RTHLYTCGTGAYKPIC-TFINRGWRAEDYLFRLVPGYVDSGKGKCSYDPNQENVASLINGNLYAG 192

  Fly   221 TVADFSGSDPIIY-----REPLQTEQYDSLSLNAPNFV-------SSFTQGDFVYFFFRETAVEF 273
            ...||..:||.|:     |..:::|||||..||.|.||       ||....|.:||||||.:::
Zfish   193 VAVDFMSTDPGIFRTMGSRPAVRSEQYDSKWLNEPVFVQMKQISDSSEKNDDKLYFFFREKSLD- 256

  Fly   274 INCGKA---IYSRVARVCKWDKGGPHRFRNRWTSFLKSRLNCSIPGD--YPFYFNEIQSASNLVE 333
             :.|.|   :.::|.|||..|:||.....|:||:|||:||.||:.||  ...:|:|::..  .::
Zfish   257 -SGGGASPSVLAKVGRVCLNDEGGQKSLVNKWTTFLKARLVCSVMGDDGVETFFDELRDV--FIQ 318

  Fly   334 GQYGSMSSKLIYGVFNTPSNSIPGSAVCAFALQDIADTFEGQFKEQTGINSNWLPVNNAKVPDPR 398
            ..... .:.::||||:|..:...|||||.:::.||.:.|.|.|..:.|.|..| .....|:|.||
Zfish   319 PSQDE-RNPIVYGVFSTSGSVFKGSAVCVYSMADIRNVFNGPFAHKHGHNYQW-TTYTGKIPYPR 381

  Fly   399 PGSCH--------NDSRALPDPTLNFIKTHSLMDENVPAFFSQPILVRTSTIYRFTQIAVDAQIK 455
            ||:|.        ..::...|..:|||:.|.||...|.....:|::||:...||||.|||| |:.
Zfish   382 PGTCPGGTFTPGLQSTKEFSDEAVNFIRAHPLMYHPVYPIHKRPLVVRSGVDYRFTTIAVD-QVD 445

  Fly   456 TPGGKTYDVIFVGTDHGKIIKSVNAESADSADKVT--SVVIEEIDVLTKSEPIRNLEIVRTMQYD 518
            ...|: |:|:|:|||.|.:.|.:....    |..|  .:.:||::|.....|::.:.|....|
Zfish   446 AVDGR-YEVLFLGTDRGTVQKVIVLPK----DPTTMEELTLEEVEVFRTPAPVKTMHISAKRQ-- 503

  Fly   519 QPKDGSYDDGKLIIVTDSQVVAIQLHRCHNDKITSCSECVALQDPYCAWD-------KIAGKCRS 576
                      :|...::..:..:.|||| .....:||:|...:|||||||       ..|.|.||
Zfish   504 ----------QLYASSEVGLTQMSLHRC-GVYGKACSDCCLARDPYCAWDGDNCSAFTQATKRRS 557

  Fly   577 ------HGAP------------RWLEENYFYQNVATGQHAAC----PSGKINSKDANAGEQKGFR 619
                  ||.|            |.|:|...:....:.....|    |...|.......|.:|...
Zfish   558 RRQDVKHGDPLRQCRGYNAKVERRLKEKVQFGVEGSSTFLECVPRSPQATIKWLYQKEGRRKVLN 622

  Fly   620 NDMDLL 625
            .|.::|
Zfish   623 RDGEVL 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1a	NP_001260265.1	Sema_1A	91..546	CDD:200498	146/481 (30%)
		PSI	545..>579	CDD:214655	17/46 (37%)
sema3ga	NP_001014823.1	Sema	50..521	CDD:301699	146/481 (30%)
		PSI	520..557	CDD:214655	14/37 (38%)
		Ig_Semaphorin_classIII	584..670	CDD:143279	8/45 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910