Protein Alignment Sema1a and sema3fa

DIOPT Version :9

• Sequence 1: NP_001260265.1
• Gene: Sema1a / 34192
• FlyBaseID: FBgn0011259
• Length: 1131
• Species: Drosophila melanogaster
• Sequence 2: XP_005166096.1
• Gene: sema3fa / 544658
• ZFINID: ZDB-GENE-050513-1
• Length: 801
• Species: Danio rerio
• Alignment Length: 1019
• Identity: 241/1019 - (23%)
• Similarity: 385/1019 - (37%)
• Gaps: 325/1019 - (31%)

  Fly    54 LLLTVLVIGNQSAWQENIRPKLYVELGPEDV------LKFVGNESVVDHFKL-----------VT 101
            |:|..|::...||...:..|  ...|.|..|      .|.:.:.....||..           :.
Zfish    12 LVLGTLLVSVFSAVSVHSSP--LSSLPPASVPRVFLSFKELKSTGTAHHFAFLLNSTDYRILRMD 74

  Fly   102 KDGNSLLIGARNTVFNLSIHDLVEQQRLV-W-TSPEDDTKMCLVKGKD-EEACQNYIRIMVVPSP 163
            :|.:.:.:|:::.:.:|.::|:.::..:: | .:|:..|: |::.||| ...|.|:||::...:.
Zfish    75 EDHDRMYVGSKDYILSLDLNDINKEPLIIHWPVAPQKRTE-CVLSGKDINGECGNFIRLIEPWNR 138

  Fly   164 GRLFVCGTNSFRPMCNTYI-----------------------ISDSN------------YTLEAT 193
            ..|:||||.::.|:| ||:                       .:|.:            :.||..
Zfish   139 THLYVCGTGAYNPIC-TYVDRGQRAQGFLQDQMPRAGGRTSRAADPSASPEPYAPKEYIFRLEPG 202

  Fly   194 K--NGQAVCPYDPRHNSTSVLADNELYSGTVADFSGSDPIIYR-----EPLQTEQYDSLSLNAPN 251
            |  :|:..|||||:.||.|.|.:.:||:|...||.|:|..|:|     ..::|:||:|..|:.|.
Zfish   203 KVDSGKGKCPYDPKLNSVSALINGQLYAGVYIDFMGTDSAIFRTLGKHTAMRTDQYNSRWLHDPT 267

  Fly   252 FV-------SSFTQGDFVYFFFRETAVEFINCGKAIYSRVARVCKWDKGGPHRFRNRWTSFLKSR 309
            ||       |:....|.:||||||.|.|......| .||:.|:|..|.||.....|:|::|||:|
Zfish   268 FVHAQLIPDSAEKNDDKLYFFFREKASEMGQTPMA-QSRIGRICLNDDGGHCCLVNKWSTFLKAR 331

  Fly   310 LNCSIPGD----------YPFYFNEIQSASNLVEGQYGSMSSKLIYGVFNTPSNSIPGSAVCAFA 364
            |.||:.|.          ...|..:.|...|.|           |||||:...:...|||||.::
Zfish   332 LICSVTGSDGIETHFDELRDVYIQKTQDTKNPV-----------IYGVFSVSGSVFKGSAVCVYS 385

  Fly   365 LQDIADTFEGQFKEQTGINSNWLPVNNAKVPDPRPGSC--------HNDSRALPDPTLNFIKTHS 421
            :.|:...|.|.|..:.|.|..|: ....|:|.||||:|        ...::..||..:||::||.
Zfish   386 MADVRMVFNGPFAHKEGPNYQWV-AYQGKIPYPRPGTCPGGTFTPNMKSTKDYPDEVINFMRTHP 449

  Fly   422 LMDENVPAFFSQPILVRTSTIYRFTQIAVDAQIKTPGGKTYDVIFVGTDHGKIIKSVNAESADSA 486
            .|...|.....:|::|||:..|.||.|.|| |:....| .|:|:|:|||.|.:.|.:.....|.
Zfish   450 TMFNAVYPVHKRPLVVRTNVDYEFTTITVD-QVAAADG-NYEVLFLGTDRGTVQKVIVLPRDDL- 511

  Fly   487 DKVTSVVIEEIDVLTKSEPIRNLEIVRTMQYDQPKDGSYDDGKLIIVTDSQVVAIQLHRC--HND 549
             :...:|:||::|......|..::|....|            :|.:.:...|..:.||||  :.:
Zfish   512 -QTEELVLEEVEVFRVPTSITTMKISPKRQ------------QLYVSSAVGVTHLALHRCDVYGE 563

  Fly   550 KITSCSECVALQDPYCAWDKIAGKCRSHGAPRWLEENYFYQNVATGQHAACPSGKINSKDANAGE 614
               :|::|...:|||||||   ||                         :|.....|.|
Zfish   564 ---ACADCCLARDPYCAWD---GK-------------------------SCSRYSANQK------ 591

  Fly   615 QKGFRNDMDLLDSRRQSKDQEIIDNIDKNFEGPQISADIINAQYTVETLVMAVLAGSIFSLLVGF 679
            ::..|.|:...:..||.:...  .|.:||               |:||:...|...:.|
Zfish   592 RRSRRQDVKYGNPIRQCRGYN--SNANKN---------------TLETVQYGVEGSTAF------ 633

  Fly   680 FTGYFCGRRCHKDEDDNLPYPDTEYEYFEQRQNVNSFPSSCRIQQEPKLLPQVEEVTYAEPVLLP 744
                                                  ..|:.:
Zfish   634 --------------------------------------LECQAR--------------------- 639

  Fly   745 QPPPPNKMHSPKNTLRKPPMHQMHQGPNSETLFQFQPDG--YNTQQSYRGRDNFGTLRSHQVMGD 807
            .|....|.|..|.              ||:...:.:.||  ..|:|..       .|||.| :.|
Zfish   640 SPHVSIKWHFQKE--------------NSDRRREIRSDGRVVRTEQGL-------LLRSLQ-LSD 682

  Fly   808 NYRRGDGFSTTRSVKKAVNNTNTRNRSLGRARRQPPRHGIVTQHRSNSPQQQQQQSQQPHSSSGS 872
            :     |.....|.:|...:|..:.:.:           :::.|..||
Zfish   683 S-----GVYQCTSTEKNFKHTLVKLQLV-----------VLSAHTVNS----------------- 714

  Fly   873 SPVMSNSSSSPAPPSSS----PSPQESPKNCSYIYRDXL-ICNTKSMPLIQAQSTHAQPHPQSHP 932
              :.:.|.:..|||..|    ||.::        |:| | |.:...|.||   :.:.|.:.|...
Zfish   715 --IQTESGAPAAPPLQSSAWTPSAEQ--------YKDLLTILSQPEMGLI---NQYCQDYWQIGD 766

  Fly   933 HPLPPPGPTTPPAQPRARSPMIGRTYAKSMPVTPVQPQSPLAET 976
            .|:..........|...|.|...|.:         |.||.:|||
Zfish   767 DPMAHKKKDLKELQKDLRKPRNRRHH---------QEQSSMAET 801

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1a	NP_001260265.1	Sema_1A	91..546	CDD:200498	153/535 (29%)
		PSI	545..>579	CDD:214655	13/35 (37%)
sema3fa	XP_005166096.1	Sema_3F	59..558	CDD:200515	152/529 (29%)
		PSI	557..594	CDD:214655	16/73 (22%)
		Ig_Semaphorin_classIII	619..709	CDD:143279	25/192 (13%)
		IG_like	623..698	CDD:214653	21/166 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.910