DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sema1a and sdf2l1

DIOPT Version :9

Sequence 1:	NP_001260265.1	Gene:	Sema1a / 34192	FlyBaseID:	FBgn0011259	Length:	1131	Species:	Drosophila melanogaster
Sequence 2:	NP_001008033.1	Gene:	sdf2l1 / 493395	XenbaseID:	XB-GENE-970744	Length:	218	Species:	Xenopus tropicalis

Alignment Length:	243	Identity:	53/243 - (21%)
Similarity:	83/243 - (34%)	Gaps:	88/243 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 GYGWMQVFLLLTVLVIGNQSAWQENIRPKLYVELGPEDVLKFVGNESVVDHFKLVTKDGNSLLIG 110
            |:|  ||||||.:..|             |:...|.|:..::|...|||.            |:.
Frog     5 GFG--QVFLLLNLCSI-------------LHRGQGSEEDAEYVTCGSVVK------------LLN 42

  Fly   111 ARNTVFNLSIHDL-----VEQQRLVWTSPEDD-TKMCLVKGKDEEACQNYIRIMVVPSPGRLFVC 169
            :|:.| .|..||:     ..||.:......|| .....::||.:..|          |.|....|
Frog    43 SRHNV-RLHSHDVKYGSGSGQQSVTGVEASDDANSYWRIRGKTDADC----------SRGEPIKC 96

  Fly   170 GTNSFRPMCNTYIISDSN-YTLEATKNGQAVCPYDPRHNSTSVLADNELYSGTVADFSGSDPIIY 233
            |    :.:..|::.:..| :|                |:..|.|::|:..|....:..|.|
Frog    97 G----QAVRLTHVNTGKNLHT----------------HHFPSPLSNNQEVSAFGDNGEGDD---- 137

  Fly   234 REPLQTEQYDSLSLNAPNFVSSFTQGDFVYFFFRETAVEFINCGKAIY 281
                         |:|.....|.|      .:.||.:|.|.:.|..:|
Frog   138 -------------LDAWMVQCSDT------LWEREESVRFKHIGTNVY 166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sema1a	NP_001260265.1	Sema_1A	91..546	CDD:200498	40/198 (20%)
Sema1a	NP_001260265.1	PSI	545..>579	CDD:214655
sdf2l1	NP_001008033.1	PMT1	<49..>209	CDD:224839	34/171 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900