Protein Alignment Sema1a and PlexB

DIOPT Version :9

• Sequence 1: NP_001260265.1
• Gene: Sema1a / 34192
• FlyBaseID: FBgn0011259
• Length: 1131
• Species: Drosophila melanogaster
• Sequence 2: NP_001245400.1
• Gene: PlexB / 43766
• FlyBaseID: FBgn0025740
• Length: 2051
• Species: Drosophila melanogaster
• Alignment Length: 585
• Identity: 126/585 - (21%)
• Similarity: 216/585 - (36%)
• Gaps: 147/585 - (25%)

  Fly    88 VGN--ESVVD-----HFKLVTKD--GNSLLIGARNTVFNLSIHDLVEQQRLV---WTSPEDDTKM 140
            :||  |||.|     :|..::.|  .|.|..||.|.:..|:     |..|::   .|.|..|:..
  Fly    71 IGNNIESVRDSQSKNYFTHMSFDFMHNVLFAGATNKILKLN-----ENLRVLAEAVTGPLHDSPQ 130

  Fly   141 CLVKGKDEE----ACQNYIRIMVV--PSPGRLFVCGTNSFRP-MCNTYIISDSNYTLEATKNGQA 198
            |...|..|:    ...|:.:|:||  ...|.|..||  |.|. .|..|.:.    ...||....|
  Fly   131 CHAGGCPEDIETSLVNNFNKILVVSYAHDGILIACG--SIRQGACEIYSLP----RFPATPQFFA 189

  Fly   199 VCPYDPRHNSTSVLA-----------DNELYSGT----VADFSGSDPIIYREPLQTEQYDSLSLN 248
            | |......:.|..|           ::.||.||    |.|:....|.|....|....|...|:.
  Fly   190 V-PLAANDENASTYAFVGPARYAWKEEDILYVGTTFTNVGDYRHDVPAISSRRLDDLNYAEFSIQ 253

  Fly   249 AP--------------NFVSSFTQGDFVYFFFRETAVEFINCGKAIY-SRVARVCKWDKGGPHRF 298
            ..              :::..|...::.||...:......:  :|.| :|:||:|..|.
  Fly   254 QSIINIDVKYRDHFLVDYIYGFNSSEYAYFIIVQKKSHLAD--EAGYVTRLARICITDP------ 310

  Fly   299 RNRWTSFLKSRLNCSIPG---DYPFYFN-EIQSASNLVEGQYGSMSSKLIYGVFNTPSNSIPG-- 357
              .:.|:.:..:.|:...   ||....: ::..||:.:..:.|......:.....:||..|..
  Fly   311 --NYDSYTEITVQCTATENNVDYNIVRDAKVTPASHKLAQKMGIKKDDHVLVTVFSPSREISNQP 373

  Fly   358 ---SAVCAFALQDIAD--------TFEGQFKEQTGINSNWL--PVNNAKVPDPRPGSCHNDSRAL 409
               ||:|.::::||.|        .|.|..|::   |..::  .:|:.:.  |..||..|
  Fly   374 ESKSAMCIYSIKDIEDMFIENIHLCFNGTTKDR---NLGYISGTINDGRC--PIVGSLGN----- 428

  Fly   410 PDPTLNFIKTHSLMDENVPAFFSQPILVRTSTIYRFTQIAVDAQIKT-PGGKTYDVIFVGTDHGK 473
               ..||......:....|        :....::.|..::|.:...| ...:.:.:.|:||:.|
  Fly   429 ---IYNFCSVGLKISGVSP--------ITAHALFHFDNVSVTSVTATSTTDQQHSLAFLGTNMG- 481

  Fly   474 IIKSVNAESADSADKVTSVVIEEIDVLTKSEPIRNLEIVRTMQYDQPKDGSYDDGKLIIVTDSQV 538
            :||.| ..|..|..:...:|::          ..|..:..||.  .||...     |.:::..::
  Fly   482 VIKKV-LLSGQSPGEYEEIVVD----------AGNRILPNTMM--SPKKDF-----LYVLSQRKI 528

  Fly   539 VAIQLHRCHNDKITSCSECVALQDPYCAWDKIAGKC-------RSHGAPRWLEENYFYQNVATGQ 596
            ..:::..|  ...|:||.|:..:||:|.|..:..:|       |...|.|||       ::.:||
  Fly   529 TKLRIEHC--SVYTNCSACLESRDPFCGWCSLEKRCTVRSTCQRDTSASRWL-------SLGSGQ 584

  Fly   597  596
              Fly   585  584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1a	NP_001260265.1	Sema_1A	91..546	CDD:200498	107/521 (21%)
		PSI	545..>579	CDD:214655	11/40 (28%)
PlexB	NP_001245400.1	Sema_plexin_like	86..534	CDD:200497	103/509 (20%)
		PSI	535..586	CDD:279745	17/59 (29%)
		PSI	683..730	CDD:214655
		PSI	836..877	CDD:214655
		IPT_plexin_repeat1	888..976	CDD:238585
		IPT_plexin_repeat2	977..1095	CDD:238584
		IPT_plexin_repeat3	1097..1211	CDD:238586
		Plexin_cytopl	1452..2017	CDD:285529

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910