Protein Alignment Sema1a and Sema2a

DIOPT Version :9

• Sequence 1: NP_001260265.1
• Gene: Sema1a / 34192
• FlyBaseID: FBgn0011259
• Length: 1131
• Species: Drosophila melanogaster
• Sequence 2: NP_477507.1
• Gene: Sema2a / 36846
• FlyBaseID: FBgn0011260
• Length: 724
• Species: Drosophila melanogaster
• Alignment Length: 607
• Identity: 219/607 - (36%)
• Similarity: 315/607 - (51%)
• Gaps: 94/607 - (15%)

  Fly    54 LLLTVLVIGNQSAWQENI------RP---------KLYVELGPEDVLKFVGNESVVDHFKLVTKD 103
            |||....:...:|..||.      ||         ..|.:.|.:.|.:|...:.....|.: .:|
  Fly    13 LLLLCSSVSETAADYENTWNFYYERPCCTGNDQGNNNYGKHGADHVREFNCGKLYYRTFHM-NED 76

  Fly   104 GNSLLIGARNTVFNLSIHDLVE---QQRLVWTSP-EDDTKMCLVKGKDE-EACQNYIRIMVVPSP 163
            .::|.:||.:.||.:::.::..   .:.::...| .||...|:.|||.: ..|:|::|::.....
  Fly    77 RDTLYVGAMDRVFRVNLQNISSSNCNRDVINLEPTRDDVVSCVSKGKSQIFDCKNHVRVIQSMDQ 141

  Fly   164 G-RLFVCGTNSFRPMCNTYII-------SDSNYTLEATKNGQAVCPYDPRHNSTSVLADN----- 215
            | ||:|||||:..|  ..|:|       ..|.|.: ....|.|.|||||..|||::..:|
  Fly   142 GDRLYVCGTNAHNP--KDYVIYANLTHLPRSEYVI-GVGLGIAKCPYDPLDNSTAIYVENGNPGG 203

  Fly   216 --ELYSGTVADFSGSDPIIYREPL-------------QTEQYDSLSLNAPNFVSSFTQGDFVYFF 265
              .|||||.|:|:.:|.:|:|..|             :|.:|||..|:.||||.||..|::||||
  Fly   204 LPGLYSGTNAEFTKADTVIFRTDLYNTSAKRLEYKFKRTLKYDSKWLDKPNFVGSFDIGEYVYFF 268

  Fly   266 FRETAVEFINCGKAIYSRVARVCKWDKGGPHRFRNRWTSFLKSRLNCSIPGDYPFYFNEIQSASN 330
            |||||||:||||||:|||:|||||.|.||.:...:.|.::||:||||||.|::|||||||||...
  Fly   269 FRETAVEYINCGKAVYSRIARVCKKDVGGKNLLAHNWATYLKARLNCSISGEFPFYFNEIQSVYQ 333

  Fly   331 LVEGQYGSMSSKLIYGVFNTPSNSIPGSAVCAFALQDIADTFEGQFKEQTGINSNWLPVNNAKVP 395
            |      .......:..|.|.:|.:.|||||:|.:.:|...|.|:||||:..||.||||.|::||
  Fly   334 L------PSDKSRFFATFTTSTNGLIGSAVCSFHINEIQAAFNGKFKEQSSSNSAWLPVLNSRVP 392

  Fly   396 DPRPGSCHNDSRALPDPTLNFIKTHSLMDENVPAFFSQPILVRTSTIYRFTQIAVDAQIKTPGGK 460
            :||||:|.||:..|||..||||::|.|||:.|....:.|:..:...:  ||::.||........:
  Fly   393 EPRPGTCVNDTSNLPDTVLNFIRSHPLMDKAVNHEHNNPVYYKRDLV--FTKLVVDKIRIDILNQ 455

  Fly   461 TYDVIFVGTDHGKIIKSV----NAESADSADKVTSVVIEEIDVLTKSEPIRNLEIVRTMQYDQPK 521
            .|.|.:|||:.|:|.|.|    |.||...        :.:|..:..:|.|:.:||.:|.:
  Fly   456 EYIVYYVGTNLGRIYKIVQYYRNGESLSK--------LLDIFEVAPNEAIQVMEISQTRK----- 507

  Fly   522 DGSYDDGKLIIVTDSQVVAIQLHRCHNDKITSCSECVALQDPYCAWDKIAGKCRSHGAPRWLEEN 586
                   .|.|.||.::..|.|..| |.:..:|..||  :||||.|||.|..||.:       |.
  Fly   508 -------SLYIGTDHRIKQIDLAMC-NRRYDNCFRCV--RDPYCGWDKEANTCRPY-------EL 555

  Fly   587 YFYQNVATGQHAACPSGKINSK 608
            ...|:||......|.|..:..|
  Fly   556 DLLQDVANETSDICDSSVLKKK 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1a	NP_001260265.1	Sema_1A	91..546	CDD:200498	185/491 (38%)
		PSI	545..>579	CDD:214655	15/33 (45%)
Sema2a	NP_477507.1	Sema_2A	66..523	CDD:200499	184/488 (38%)
		Ig_Semaphorin_C	573..664	CDD:143180	1/5 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462130
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D153798at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850