Protein Alignment Sema1a and Sema3f

DIOPT Version :9

• Sequence 1: NP_001260265.1
• Gene: Sema1a / 34192
• FlyBaseID: FBgn0011259
• Length: 1131
• Species: Drosophila melanogaster
• Sequence 2: XP_038937516.1
• Gene: Sema3f / 315996
• RGDID: 1308514
• Length: 802
• Species: Rattus norvegicus
• Alignment Length: 987
• Identity: 242/987 - (24%)
• Similarity: 392/987 - (39%)
• Gaps: 326/987 - (33%)

  Fly    53 FLLLTVLVIGNQSAW-----QENI----RPKL-YVEL---GPEDVLKFVGNESVVDHFKLVTK-- 102
            |:|...|:.|   ||     |:.:    |.:| :.||   |......|:.|.:   .::::.|
  Rat    23 FILWASLLTG---AWPAAPIQDQLPATPRVRLSFKELKATGTAHFFNFLLNTT---DYRILFKDE 81

  Fly   103 DGNSLLIGARNTVFNLSIHDLVEQQRLV-WTSPEDDTKMCLVKGKDEEA-CQNYIRIMVVPSPGR 165
            |.:.:.:|:::.|.:|.:||:..:..:: |.:.....:.|::.|||... |.|::|::...:...
  Rat    82 DHDRMYVGSKDYVLSLDLHDINREPLIIHWAASPQRIEECILSGKDGNGECGNFVRLIQPWNRTH 146

  Fly   166 LFVCGTNSFRPMCNTYI------------------------------------ISDSNYTLEATK 194
            |:||||.::.||| ||:                                    ..|..:.||..|
  Rat   147 LYVCGTGAYNPMC-TYVNRGRRSQAPPWTQMQVVRGRGSRATDGADRPTPTAPRQDYIFYLEPEK 210

  Fly   195 --NGQAVCPYDPRHNSTSVLADNELYSGTVADFSGSDPIIYR-----EPLQTEQYDSLSLNAPNF 252
              :|:..|||||:.::.|.|.:.|||:|...||.|:|..|:|     ..::|:||:|..||.|:|
  Rat   211 LESGKGKCPYDPKLDTASALINEELYAGVYIDFMGTDAAIFRTLGKQTAMRTDQYNSRWLNDPSF 275

  Fly   253 V-------SSFTQGDFVYFFFRETAVEFINCGKAIYSRVARVCKWDKGGPHRFRNRWTSFLKSRL 310
            :       |:....|.:||||||.:.|... ..|:|:|:.|:|..|.||.....|:|::|||:||
  Rat   276 IHAELIPDSAERNDDKLYFFFRERSAEAPQ-NPAVYARIGRICLNDDGGHCCLVNKWSTFLKARL 339

  Fly   311 NCSIPGD--YPFYFNEIQSASNLVEGQYGSMSSKLIYGVFNTPSNSIPGSAVCAFALQDIADTFE 373
            .||:||:  ...:|:|:|   ::...|...:.:.:||.||.:..:...|||||.:::.||...|.
  Rat   340 VCSVPGEDGIETHFDELQ---DVFVQQTQDVRNPVIYAVFTSSGSVFRGSAVCVYSMADIRMVFN 401

  Fly   374 GQFKEQTGINSNWLPVNNAKVPDPRPGSC--------HNDSRALPDPTLNFIKTHSLMDENVPAF 430
            |.|..:.|.|..|:|. :.|:|.||||:|        ...::..||..:||::||.||.:.|...
  Rat   402 GPFAHKEGPNYQWMPF-SGKMPYPRPGTCPGGTFTPSMKSTKDYPDEVINFMRTHPLMYQAVYPL 465

  Fly   431 FSQPILVRTSTIYRFTQIAVDAQIKTPGGKTYDVIFVGTDHGKIIKSVNAESADSADKVTSVVIE 495
            ..:|::|||...||.|.:||| |:....|: |:|:|:|||.|.:.|.:.....|  .:|..:::|
  Rat   466 QRRPLVVRTGAPYRLTTVAVD-QVDAADGR-YEVLFLGTDRGTVQKVIVLPKDD--QEVEELMLE 526

  Fly   496 EIDVLTKSEPIRNLEIVRTMQYDQPKDGSYDDGKLIIVTDSQVVAIQLHRCHNDKITSCSECVAL 560
            |::|..:..|::.:.|....|            :|.:.:...|..:.||||.... .:|::|...
  Rat   527 EVEVFKEPAPVKTMTISSKRQ------------QLYVASAVGVTHLSLHRCQAYG-AACADCCLA 578

  Fly   561 QDPYCAWDKIAGKCRSHGAPRWLEENYFYQNVATGQHAACPSGKINSKDANAGEQKGFRNDMDLL 625
            :|||||||                          ||  ||.....:||
  Rat   579 RDPYCAWD--------------------------GQ--ACSRYTASSK----------------- 598

  Fly   626 DSRRQSKDQEIIDNIDKNFEGPQISADIINAQYTVETLVMAVLAGSIFSLLVGFFTGYFCGRRCH 690
               |:|:.|::       ..|..|                                     |:|.
  Rat   599 ---RRSRRQDV-------RHGNPI-------------------------------------RQCR 616

  Fly   691 KDEDDNLPYPDTEYEYFEQRQNVNSFPSSCRIQQEPKLLPQVEEVTY----AEPVLLPQPPPPNK 751
            .               |....|.|:                :|.|.|    :...|..||
  Rat   617 G---------------FNSNANKNA----------------IESVQYGVAGSAAFLECQP----- 645

  Fly   752 MHSPKNTLRKPPMHQMHQGPNSETLFQFQPDGYNTQQSYRGRDNFGTLRSHQ-------VMGDNY 809
             .||:.|::                :.||.|..:.::..|..|.|  ||:.|       .:||
  Rat   646 -RSPQATVK----------------WLFQRDPSDRRREIRAEDRF--LRTEQGLLLRALQLGD-- 689

  Fly   810 RRG--DGFSTTRSVKKAVNNTNTRNRSLGR----ARRQPPRHGIVTQHRSNSPQQQQQQSQQPHS 868
             ||  ...:|..:.|..|  |..:...|||    |...||.
  Rat   690 -RGLYSCTATENNFKHVV--TRVQLHVLGRDAVHAALFPPL------------------------ 727

  Fly   869 SSGSSPVMSNSSSSPAPPSSSPSPQESPKNCSYIYRDXLICNTKSMPLI-------QAQSTHAQP 926
                      :.|.|.||.:.|   .:|.     |::  :....:.|.:       |....|..|
  Rat   728 ----------AVSVPPPPGTGP---PTPP-----YQE--LAQLLAQPEVGLIHQYCQGYWRHVPP 772

  Fly   927 HPQSHPHPLPPP 938
            :|:..|..|.||
  Rat   773 NPREAPGALRPP 784

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1a	NP_001260265.1	Sema_1A	91..546	CDD:200498	153/518 (30%)
		PSI	545..>579	CDD:214655	11/33 (33%)
Sema3f	XP_038937516.1	Sema_3F	65..565	CDD:200515	155/524 (30%)
		PSI	564..601	CDD:214655	18/85 (21%)
		Ig_Sema3	625..714	CDD:409455	27/133 (20%)
		Ig strand B	639..643	CDD:409455	1/3 (33%)
		Ig strand C	651..655	CDD:409455	1/19 (5%)
		Ig strand E	678..682	CDD:409455	1/3 (33%)
		Ig strand F	692..697	CDD:409455	0/4 (0%)
		Ig strand G	709..712	CDD:409455	0/2 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910