Protein Alignment Sema1a and Sema7a

DIOPT Version :9

• Sequence 1: NP_001260265.1
• Gene: Sema1a / 34192
• FlyBaseID: FBgn0011259
• Length: 1131
• Species: Drosophila melanogaster
• Sequence 2: NP_001101623.1
• Gene: Sema7a / 315711
• RGDID: 1305192
• Length: 666
• Species: Rattus norvegicus
• Alignment Length: 631
• Identity: 154/631 - (24%)
• Similarity: 268/631 - (42%)
• Gaps: 106/631 - (16%)

  Fly    50 MQVFLLLTVLVIGNQSAWQENIRPKLYVELGPEDVLKFVGNESVVDHFKLVTKDGN-SLLIGARN 113
            :::.|||...|....:.......|::......:|.:.|...|   .|..|..:.|: |:.:|.|.
  Rat    29 LRLRLLLVFWVTAASAQGHSRSGPRISAVWKGQDHVDFGQPE---PHNVLFHEPGSFSVWVGGRG 90

  Fly   114 TVFNLSIHDLVEQQRLVWTSPED------DTKMCLVKG--KDEEACQNYIRIMVVPSPGRLFVCG 170
            .|:             ::..||.      ...:...||  :|::.|:|||.::.....| |.|||
  Rat    91 KVY-------------LFNFPEGKNASVRTVNIGSTKGSCQDKQDCENYITLLERRGNG-LLVCG 141

  Fly   171 TNSFRPMCNTYIISDSNYTLEATKNGQAVCPYDPRHNSTSVLADNELYSGTV--ADFSGSDPIIY 233
            ||:.:|.| ..:::||.........|.|  |:.|..||..:...:|:|| |:  .:::|..|...
  Rat   142 TNARKPSC-WNLVNDSVVMSLGEMKGYA--PFSPDENSLVLFEGDEVYS-TIRKQEYNGKIPRFR 202

  Fly   234 REPLQTEQY--DSLSLNAPNFVSSF------TQGDFVYFFFRETAVEFINCGKAIYSRVARVCKW 290
            |...::|.|  |::..| |.|:.:.      ...|.:|:||||...:.........||||::|:.
  Rat   203 RIRGESELYTSDTVMQN-PQFIKATIVHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRG 266

  Fly   291 DKGGPHRFR-NRWTSFLKSRLNCSIPGDYPFYFNEIQSASNLVEGQYGSMSSKLIYGVFNTPSNS 354
            |:||..... ::|.:|||:.|.||...... .||.:|... |:....|......:||||:.|.|.
  Rat   267 DQGGESSLSVSKWNTFLKAMLVCSDAATNR-NFNRLQDVF-LLPDPSGQWRDTRVYGVFSNPWNY 329

  Fly   355 IPGSAVCAFALQDIADTFEGQFKEQTGINSNWLPVNNAKVPDPRPGSCHNDSRALPDPTLNFIKT 419
               ||||.::|.||...|          .::.|...:..:|:||||.|....:.:|..|.....:
  Rat   330 ---SAVCVYSLGDIDRVF----------RTSSLKGYHMGLPNPRPGMCLPKKQPIPTETFQVADS 381

  Fly   420 HSLMDENV--------PAFFSQPILVRTSTIYRFTQIAVDAQIKTPGGKTYDVIFVGTDHGKIIK 476
            |..:.:.|        |.|.|:         |.:.::.|. :::...|:|:.|:::.||.|.|.|
  Rat   382 HPEVAQRVEPMGPLKTPLFHSK---------YHYQKVVVH-RMQASNGETFHVLYLTTDRGTIHK 436

  Fly   477 SVNAESADSADKVTSVVIEEIDVLTKSEPIRNLEIVRTMQYDQPKDGSYDDGKLIIVTDSQVVAI 541
            .|     :|.|:..|.|...:::    :|......::.:..|.      |..||.:.:..:|..:
  Rat   437 VV-----ESGDQEHSFVFNIMEI----QPFHRAAAIQAISLDA------DRRKLYVTSPWEVSQV 486

  Fly   542 QLHRCHNDKITS--CSECVALQDPYCAWDKIAGKCRSHGAPRWLEENYFYQNVATGQ-HAACPSG 603
            .|..|   .:.|  |..|:..:||||.||:...:|.|    .:..:....|::...: |..||:.
  Rat   487 PLDMC---GVYSGGCHGCLMSRDPYCGWDQDQDRCVS----IYSSQRSVLQSINPAEPHRECPNP 544

  Fly   604 KINSKDANAGEQKGFRNDMDLLDSRRQSKDQEII----DNIDKNFE 645
              |..:|...:....||....|....:|:....:    :|::::.|
  Rat   545 --NPDEAPLQKVSLARNSRYYLTCPMESRHATYLWRHEENVEQSCE 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1a	NP_001260265.1	Sema_1A	91..546	CDD:200498	123/482 (26%)
		PSI	545..>579	CDD:214655	12/35 (34%)
Sema7a	NP_001101623.1	PSI	491..>520	CDD:279745	11/31 (35%)
		Ig	549..622	CDD:299845	7/40 (18%)
		Sema_7A	70..489	CDD:200504	122/480 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000