Protein Alignment Sema1a and sema3d

DIOPT Version :9

• Sequence 1: NP_001260265.1
• Gene: Sema1a / 34192
• FlyBaseID: FBgn0011259
• Length: 1131
• Species: Drosophila melanogaster
• Sequence 2: NP_571123.2
• Gene: sema3d / 30250
• ZFINID: ZDB-GENE-990715-2
• Length: 764
• Species: Danio rerio
• Alignment Length: 615
• Identity: 194/615 - (31%)
• Similarity: 308/615 - (50%)
• Gaps: 112/615 - (18%)

  Fly    49 WMQVFLLLTVLVIGNQSAWQENIRPKLYVELGPED------VLKFVGNESVVDHFK--LVTKDGN 105
            |....:|...|..||  ..:|:: |:  |:||.:|      |:.|.|: |...||:  |:.::.:
Zfish    26 WSTSVMLFFSLPEGN--CMKESL-PR--VKLGYKDLIHSRSVVPFTGS-SEGQHFQTVLLDEERS 84

  Fly   106 SLLIGARNTVF-----NLSIHDLVEQQRLVWTSPEDDTKMCLVKGKDE-EACQNYIRIMVVPSPG 164
            .||:||::.|:     |::.|    .::|.|.:..|..:||::.||:. ..|.|:||::...:..
Zfish    85 RLLLGAKDHVYLLDPDNINKH----PKKLSWPASRDRVEMCILAGKNPLTECANFIRVLHSYNRT 145

  Fly   165 RLFVCGTNSFRPMC----------NTYIISDSNYTLEATKNGQAVCPYDPRHNSTSVLADNELYS 219
            .::.|||.:|.|.|          :.::...|| |:|   :|:..||:||.....|||.|..||:
Zfish   146 HVYACGTGAFHPTCAFLEIKGHKEDRWLQLHSN-TME---SGRMKCPFDPNQPFASVLTDQYLYA 206

  Fly   220 GTVADFSGSD--------PIIYREPLQTEQYDSLSLNAPNFVSSF-------TQGDFVYFFFRET 269
            ||.:||.|.|        |..:::.::|:..:...:|...|:|:.       ...|.:||||||.
Zfish   207 GTASDFLGKDSTFTRSLGPPPHQQYIRTDISEDYWINEGKFISAHPISDTYNPDDDKIYFFFREA 271

  Fly   270 AVEFINCGKAIYSRVARVCKWDKGGPHRFRNRWTSFLKSRLNCSIPG--DYPFYFNEIQSASNLV 332
            :.:.....|::.|||||:|:.|.||.....|:||:|||:||.|||||  ....:|:|:|....|
Zfish   272 SRDGSTTDKSVLSRVARICRNDVGGLRSLTNKWTTFLKARLVCSIPGPDGVDTHFDELQDIFLL- 335

  Fly   333 EGQYGSMSSK--LIYGVFNTPSNSIPGSAVCAFALQDIADTFEGQFKEQTGINSNWLPVNNAKVP 395
                .|...|  ::||||.|.|:...|||||.:.::||...|.|.:..:.|.:..|:.. ..::|
Zfish   336 ----PSRDEKNPMVYGVFTTTSSIFKGSAVCVYTMEDIRAAFNGPYAHKEGPDHRWVEY-EGRIP 395

  Fly   396 DPRPGSCHN--------DSRALPDPTLNFIKTHSLMDENVPAFFSQPILVRTSTIYRFTQIAVDA 452
            .||||:|.:        .::..||..::||:.|.||.::|.....:||..|.:|.||.|||.||
Zfish   396 YPRPGTCPSRTYDPHIKTTKDFPDEVISFIRLHPLMYQSVHPMTGRPIFTRINTEYRLTQIIVD- 459

  Fly   453 QIKTPGGKTYDVIFVGTDHGKIIK--SVNAESADSADKVTSVVIEEIDVLTKSEPIRNLEIVRTM 515
            ::....|: |.|:|:|||.|.::|  |:..|:..|.:    :::||:.|.....||.|:|:....
Zfish   460 RVAAEDGQ-YAVMFLGTDMGSVLKVVSITQENWSSEE----IILEELQVFKNPSPILNMEVSSKQ 519

  Fly   516 QYDQPKDGSYDDGKLIIVTDSQVVAIQLHRCHNDKI--TSCSECVALQDPYCAWDKI-------A 571
            |            :|.:.....:|.:.|||||   |  ..|:||...:|||||||..       |
Zfish   520 Q------------QLFVGGSDGLVQVSLHRCH---IYGQGCAECCLARDPYCAWDGTQCSRYIPA 569

  Fly   572 GKCRS------HGAPR---WLEENYFYQNV 592
            .|.|:      ||.|.   |..|:...:||
Zfish   570 SKRRARRQDIKHGDPSSHCWDTEDVLGRNV 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1a	NP_001260265.1	Sema_1A	91..546	CDD:200498	156/501 (31%)
		PSI	545..>579	CDD:214655	18/48 (38%)
sema3d	NP_571123.2	Sema_3D	65..538	CDD:200513	158/505 (31%)
		PSI	537..589	CDD:214655	20/54 (37%)
		Ig_Semaphorin_classIII	599..689	CDD:143279	1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	743..764

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D153798at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.020