Protein Alignment Sema1a and Sema4c

DIOPT Version :9

• Sequence 1: NP_001260265.1
• Gene: Sema1a / 34192
• FlyBaseID: FBgn0011259
• Length: 1131
• Species: Drosophila melanogaster
• Sequence 2: XP_006244820.1
• Gene: Sema4c / 301346
• RGDID: 1562837
• Length: 856
• Species: Rattus norvegicus
• Alignment Length: 611
• Identity: 204/611 - (33%)
• Similarity: 298/611 - (48%)
• Gaps: 110/611 - (18%)

  Fly    41 LSKFYGYG---------WMQ-------VFLL---LTVLVIGNQSAWQENIRPKLYVELGP-EDVL 85
            |:.|:.:.         |:.       |:||   |..|.||.:..|  |:.|:..|..|. ..|:
  Rat     2 LTSFFSFSRAAGLKFRLWVSAMAPHWAVWLLAAGLWGLGIGAEMWW--NLAPRKTVSSGELVTVV 64

  Fly    86 KFVGNESVVDHFKLVTKDGNSLL-IGARNTVFNLSIHDLVEQQRLVWTSPEDDTKMCLVKGKDEE 149
            :......:.|...|...|.:.|| :|||..:|..|:..|..|..:.|.:|.:....|..|||..:
  Rat    65 RRFSQTGIQDFLTLTLTDRSGLLYVGAREALFAFSVEALELQGVISWEAPAEKKIECTQKGKSNQ 129

  Fly   150 A-CQNYIRIMVVPSPGRLFVCGTNSFRPMCNTYIISDSNYTLEAT--KNGQAVCPYDPRHNSTSV 211
            . |.|:||.:...:...|:||||.:|:|.| || |:...:||:..  ::|:..|||||....|.:
  Rat   130 TECFNFIRFLQPYNASHLYVCGTYAFQPKC-TY-INMLTFTLDRAEFEDGKGKCPYDPAKGHTGL 192

  Fly   212 LADNELYSGTVADFSGSDPIIYR-----EPLQTEQYDSLSLNAPNF---------VSSFT-QGDF 261
            |.|.||||.|:.:|.|::|:|.|     .|::|| |.:..||.|:|         |.||| ..|.
  Rat   193 LVDGELYSATLNNFLGTEPVILRNMGPHHPIKTE-YLAFWLNEPHFVGSAFVPESVGSFTGDDDK 256

  Fly   262 VYFFFRETAVEFINCGKAIYSRVARVCKWDKGGPHRFRNRWTSFLKSRLNCSIPGDYPFYFNEIQ 326
            :||||.|.|||:....:.:.:|||||||.|.||....:.:||:|||:||.||.| |:..|||:::
  Rat   257 IYFFFSERAVEYDCYSEQVVARVARVCKGDMGGARTLQKKWTTFLKARLVCSAP-DWKVYFNQLR 320

  Fly   327 SASNLVEGQYGSMSSKLIYGVFNTPSNSIPGSAVCAFALQDIADTFEGQFKEQTGINSNWLPVNN 391
            :...|:.   .|..:...:.||......:..||||.:.|:.|...|||.|||.:.....|....:
  Rat   321 AVHTLLG---ASWHNTTFFAVFQARWGDMDLSAVCEYQLEHIQQVFEGPFKEYSEQAQKWARYTD 382

  Fly   392 AKVPDPRPGSC----HND-----SRALPDPTLNFIKTHSLMDENVPAFFSQPILVRTSTIYRFTQ 447
             .||.||||||    |.|     |..|||.||||||.|.||:|.|.....:|:||:.:|  .||.
  Rat   383 -PVPTPRPGSCINNWHRDNGYTSSLELPDNTLNFIKKHPLMEEQVKPRLGRPLLVKKNT--NFTH 444

  Fly   448 IAVDAQIKTPGGKTYDVIFVGTDHGKIIKSVNAESADSADKVTSV-----VIEEIDVLTKSEPIR 507
            :..| :|....|.||.|:|:||..|.::|:|            |:     ::||:.|..: ||:.
  Rat   445 VVAD-RILGLDGATYTVLFIGTGDGWLLKAV------------SLGPWIHMVEELQVFDQ-EPVE 495

  Fly   508 NLEIVRTMQYDQPKDGSYDDGKLIIVTDSQVVAIQLHRCHNDKITSCSECVALQDPYCAWDKIAG 572
            :|.:.::.:.            |...:.||:|.:.|..|  .|...|.:||..:||||||:....
  Rat   496 SLVLSQSKKV------------LFAGSRSQLVQLSLADC--TKYRFCVDCVLARDPYCAWNVNTS 546

  Fly   573 KCRSHGAPRWLEENYFYQNVATGQHA 598
            :|                 ||||.|:
  Rat   547 RC-----------------VATGGHS 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1a	NP_001260265.1	Sema_1A	91..546	CDD:200498	171/487 (35%)
		PSI	545..>579	CDD:214655	12/33 (36%)
Sema4c	XP_006244820.1	Sema_4C	64..520	CDD:200519	170/491 (35%)
		PSI	521..>550	CDD:214655	12/47 (26%)
		IG_like	585..659	CDD:214653
		Ig	586..670	CDD:299845

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910