Protein Alignment Sema1a and Sema3c

DIOPT Version :9

• Sequence 1: NP_001260265.1
• Gene: Sema1a / 34192
• FlyBaseID: FBgn0011259
• Length: 1131
• Species: Drosophila melanogaster
• Sequence 2: XP_008760867.1
• Gene: Sema3c / 296787
• RGDID: 1309343
• Length: 760
• Species: Rattus norvegicus
• Alignment Length: 595
• Identity: 176/595 - (29%)
• Similarity: 291/595 - (48%)
• Gaps: 105/595 - (17%)

  Fly    99 LVTKDGNSLLIGARNTVFNLSIHDLVEQQRLV-WTSPEDDTKMCLVKGKD-EEACQNYIRIMVVP 161
            |:.:|.:.:.:|:::.:.:|:|:::.::...| |.:.....:.|.:.||| ...|.|::|::...
  Rat    64 LMDEDQDRIYVGSKDHILSLNINNISQEPLSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTF 128

  Fly   162 SPGRLFVCGTNSFRPMCNTYI-----ISDSNYTLEA-TKNGQAVCPYDPRHNSTSVLADNELYSG 220
            :...|:|||:.:|.|:| ||:     ..|..:.::: .::|:..|.::|..|:.||:.:.||:||
  Rat   129 NRTHLYVCGSGAFSPVC-TYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINEELFSG 192

  Fly   221 TVADFSGSDPIIY-----REPLQTEQYDSLSLNAPNFVSSFTQGD-------FVYFFFRETAVEF 273
            ...||.|:|..|:     |..::|:|::|..|:.|.||.:....|       .|||||:|...:.
  Rat   193 MYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKERLTDN 257

  Fly   274 INCGKAIYSRVARVCKWDKGGPHRFRNRWTSFLKSRLNCSIPG-DYP-FYFNEIQSASNLVEGQY 336
            ....|.|:|.|||:|..|.||.....|:||:|||:||.||:.. |.| .:|:|::....|   :.
  Rat   258 NRSTKQIHSMVARICPNDTGGQRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLL---ET 319

  Fly   337 GSMSSKLIYGVFNTPSNSIPGSAVCAFALQDIADTFEGQFKEQTGINSNWLPVNNAKVPDPRPGS 401
            .:..:.|:||:|.|.|:...|||||.:.|.||...|.|.|..:.|.|...:.. ..::|.||||:
  Rat   320 DNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISY-QGRIPYPRPGT 383

  Fly   402 C--------HNDSRALPDPTLNFIKTHSLMDENVPAFFSQPILVRTSTIYRFTQIAVDAQIKTPG 458
            |        ...::..||..:.||:.|.||..::.....:|::||..|.|::|:|||| ::....
  Rat   384 CPGGAFTPNMRTTKDFPDDVVTFIRNHPLMYNSIYPIHRRPLIVRIGTDYKYTKIAVD-RVNAAD 447

  Fly   459 GKTYDVIFVGTDHGKIIKSVNAESADSADKVTSVVIEEIDVLTKSEPIRNLEIVRTMQYDQPKDG 523
            |: |.|:|:|||.|.:.|.|...:..||.  ..:::||::|.....||..::|....|
  Rat   448 GR-YHVLFLGTDRGTVQKVVVLPTNSSAS--GELILEELEVFKNHVPITTMKISSKKQ------- 502

  Fly   524 SYDDGKLIIVTDSQVVAIQLHRCHNDKI--TSCSECVALQDPYCAWDKIAGKCRSHGAPRWLEEN 586
                 :|.:.::..|..:.|||||   |  |:|::|...:|||||||       .|...|
  Rat   503 -----QLYVSSNEGVSQVSLHRCH---IYGTACADCCLARDPYCAWD-------GHSCSR----- 547

  Fly   587 YFYQNVATGQHAACPSGKINSKD-----------------------ANAGE--QKGFRNDMDLLD 626
             ||           |:||..|:.                       .||.|  |.|.||:...|:
  Rat   548 -FY-----------PTGKRRSRRQDVRHGNPLTQCRGFNLKGMRAYRNAAEIVQYGVRNNSTFLE 600

  Fly   627 SRRQSKDQEI 636
            ...:|....|
  Rat   601 CAPKSPQASI 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1a	NP_001260265.1	Sema_1A	91..546	CDD:200498	144/476 (30%)
		PSI	545..>579	CDD:214655	15/35 (43%)
Sema3c	XP_008760867.1	Sema_3C	51..520	CDD:200512	144/476 (30%)
		PSI	519..556	CDD:214655	21/63 (33%)
		Ig_Semaphorin_classIII	584..673	CDD:143279	9/27 (33%)
		IG_like	588..662	CDD:214653	7/23 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.910