Protein Alignment Sema1a and Sema3c

DIOPT Version :9

• Sequence 1: NP_001260265.1
• Gene: Sema1a / 34192
• FlyBaseID: FBgn0011259
• Length: 1131
• Species: Drosophila melanogaster
• Sequence 2: NP_038685.3
• Gene: Sema3c / 20348
• MGIID: 107557
• Length: 751
• Species: Mus musculus
• Alignment Length: 592
• Identity: 175/592 - (29%)
• Similarity: 291/592 - (49%)
• Gaps: 102/592 - (17%)

  Fly    99 LVTKDGNSLLIGARNTVFNLSIHDLVEQQRLV-WTSPEDDTKMCLVKGKD-EEACQNYIRIMVVP 161
            |:.:|.:.:.:|:::.:.:|:|:::.::...| |.:.....:.|.:.||| ...|.|::|::...
Mouse    58 LMDEDQDRIYVGSKDHILSLNINNISQEPLSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTF 122

  Fly   162 SPGRLFVCGTNSFRPMCNTYI-----ISDSNYTLEA-TKNGQAVCPYDPRHNSTSVLADNELYSG 220
            :...|:|||:.:|.|:| ||:     ..|..:.::: .::|:..|.::|..|:.||:.:.||:||
Mouse   123 NRTHLYVCGSGAFSPVC-TYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINEELFSG 186

  Fly   221 TVADFSGSDPIIY-----REPLQTEQYDSLSLNAPNFVSSFTQGD-------FVYFFFRETAVEF 273
            ...||.|:|..|:     |..::|:|::|..|:.|.||.:....|       .|||||:|...:.
Mouse   187 MYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKERLTDN 251

  Fly   274 INCGKAIYSRVARVCKWDKGGPHRFRNRWTSFLKSRLNCSIPG-DYP-FYFNEIQSASNLVEGQY 336
            ....|.|:|.:||:|..|.||.....|:||:|||:||.||:.. |.| .:|:|::....|   :.
Mouse   252 NRSTKQIHSMIARICPNDTGGQRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLL---ET 313

  Fly   337 GSMSSKLIYGVFNTPSNSIPGSAVCAFALQDIADTFEGQFKEQTGINSNWLPVNNAKVPDPRPGS 401
            .:..:.|:||:|.|.|:...|||||.:.|.||...|.|.|..:.|.|...:.. ..::|.||||:
Mouse   314 DNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISY-QGRIPYPRPGT 377

  Fly   402 C--------HNDSRALPDPTLNFIKTHSLMDENVPAFFSQPILVRTSTIYRFTQIAVDAQIKTPG 458
            |        ...::..||..:.||:.|.||..::.....:|::||..|.|::|:|||| ::....
Mouse   378 CPGGAFTPNMRTTKDFPDDVVTFIRNHPLMYNSIYPIHRRPLIVRIGTDYKYTKIAVD-RVNAAD 441

  Fly   459 GKTYDVIFVGTDHGKIIKSVNAESADSADKVTSVVIEEIDVLTKSEPIRNLEIVRTMQYDQPKDG 523
            |: |.|:|:|||.|.:.|.|...:..||.  ..:::||::|.....||..::|....|
Mouse   442 GR-YHVLFLGTDRGTVQKVVVLPTNSSAS--GELILEELEVFKNHVPITTMKISSKKQ------- 496

  Fly   524 SYDDGKLIIVTDSQVVAIQLHRCHNDKI--TSCSECVALQDPYCAWDKIAGKCRSHGAPRWLEEN 586
                 :|.:.::..|..:.|||||   |  |:|::|...:|||||||       .|...|
Mouse   497 -----QLYVSSNEGVSQVSLHRCH---IYGTACADCCLARDPYCAWD-------GHSCSR----- 541

  Fly   587 YFYQNVATGQHAACPSGKINSKD--------------------ANAGE--QKGFRNDMDLLDSRR 629
             ||           |:||..|:.                    .||.|  |.|.||:...|:...
Mouse   542 -FY-----------PTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNAAEIVQYGVRNNSTFLECAP 594

  Fly   630 QSKDQEI 636
            :|....|
Mouse   595 KSPQASI 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1a	NP_001260265.1	Sema_1A	91..546	CDD:200498	143/476 (30%)
		PSI	545..>579	CDD:214655	15/35 (43%)
Sema3c	NP_038685.3	Sema_3C	45..514	CDD:200512	143/476 (30%)
		PSI	513..550	CDD:214655	21/63 (33%)
		Ig_Semaphorin_classIII	575..664	CDD:143279	9/27 (33%)
		IG_like	579..653	CDD:214653	7/23 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910