Protein Alignment Sema1a and smp-1

DIOPT Version :9

• Sequence 1: NP_001260265.1
• Gene: Sema1a / 34192
• FlyBaseID: FBgn0011259
• Length: 1131
• Species: Drosophila melanogaster
• Sequence 2: NP_001379344.1
• Gene: smp-1 / 173351
• WormBaseID: WBGene00004889
• Length: 714
• Species: Caenorhabditis elegans
• Alignment Length: 653
• Identity: 232/653 - (35%)
• Similarity: 350/653 - (53%)
• Gaps: 84/653 - (12%)

  Fly    55 LLTVLVIGNQSAWQE-------NIRPKLYV-ELGPEDVLKFVGNES-VVDHFKLVTKDGNSLLIG 110
            :||:|::.|.....|       |:|||..: .:|..|....:|..| ..|||||:..||:|||:|
 Worm     4 ILTLLLLFNVVRSSEAITGGVVNLRPKQIINSVGIGDRFGGIGTSSDESDHFKLLAADGDSLLVG 68

  Fly   111 ARNTVFNLSIHDLVEQQRLVWTSPEDDTKMCLVKGKDEEACQNYIRIMVVPSPGRLFVCGTNSFR 175
            |||.|:|||:..|....::.|..|.:..:.|::|||.:..||||||::...|.|...||||::|.
 Worm    69 ARNAVYNLSLSTLSVNHKIDWKPPAEHIEECIMKGKSKTDCQNYIRVLARKSAGVSLVCGTHAFS 133

  Fly   176 PMCNTYIISDSNYTLEATKNGQAVCPYDPRHNSTS--VLADNELYSGTVADFSGSDPIIYREP-- 236
            |.|..|.:::.........:||.:.||||:|||::  |...|:|:..||.||.|:|.:|||:.
 Worm   134 PKCREYTVTEFGIRNTRQFDGQGISPYDPKHNSSALYVPGTNQLFVATVTDFVGNDALIYRKTID 198

  Fly   237 ----------LQTEQYDSLSLNAPNFVSSFTQGDFVYFFFRETAVEFI--NCGKAIYSRVARVCK 289
                      ::|:.||:..|||||||::|...:.|||:|||.|.|.|  |....||:|||||||
 Worm   199 ETPSSKSAANIRTQSYDARVLNAPNFVATFAYKEHVYFWFREIASEAIDNNEEPQIYARVARVCK 263

  Fly   290 WDKGGPHRFRNRWTSFLKSRLNCSIP-GDYPFYFNEIQSASNLVEGQYGSMSSKLIYGVFNTPSN 353
            .||||......||||:||:|||||:| |..||||||:::.|:.::   ...::.::|.||:||.:
 Worm   264 NDKGGARPANERWTSYLKARLNCSLPSGSSPFYFNELKAVSDPID---AGNNNHVVYTVFSTPDS 325

  Fly   354 SIPGSAVCAFALQDIADTFE-GQFKEQTGINSNWLPVNNAKVPDPRPGSCHNDSRALPDPTLNFI 417
            .:..||||.|:::.|.:.|: |.||.|....|.|:..|..:||.||||||..||..||:.|::||
 Worm   326 DVRMSAVCKFSMKKIREEFDNGTFKHQNNAQSMWMAFNRNEVPKPRPGSCSPDSTKLPENTVSFI 390

  Fly   418 KTHSLMDENVPAFFSQPILVRTSTIYRFTQIAVDAQIKTPGGKTYDVIFVGTDHGKIIKSVNAES 482
            ..|.|:...:|: .:.|:||..:.....|||.|..:::..||..||::|:||..||::|.|..:.
 Worm   391 LHHPLLHRPIPS-VAAPLLVEGADRADLTQITVLPRVRAVGGHNYDILFIGTSDGKVLKVVEVDG 454

  Fly   483 ADSADKVTSVVIEEIDVLTKSEPIRNLEIVRTMQYDQPKDGSYDDGKLIIVTDSQVVAIQLHRCH 547
                   .:.||:...|..:..||.||...:.              .::||:..::.::.:|.|.
 Worm   455 -------NATVIQSATVFQRGVPIVNLLTTKE--------------SVVIVSADEIASLPVHNCA 498

  Fly   548 NDKITSCSECVALQDPYCAWDKIAGKCRSHGAPRWLEENYFYQNVATGQHAACPSGKINSKDANA 612
            ..  ||||:||.||||:||||....:| .||. .|..:. |.||:..||...||.|.|
 Worm   499 QQ--TSCSKCVQLQDPHCAWDSSIARC-VHGG-SWTGDQ-FIQNMVFGQSEQCPEGII------- 551

  Fly   613 GEQKGFRNDMDLLDSRRQSKDQEIIDNIDKNFEGPQISADIINAQYTVETLVMAVLAGSIFSLLV 677
                                .:|:.|:.:...:...:|......:::..|:|:.....|:.||::
 Worm   552 --------------------VREVFDDNESEAQPEAVSRSGYPKEHSTITVVLVAAVASLISLII 596

  Fly   678 GFF 680
            |.|
 Worm   597 GAF 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1a	NP_001260265.1	Sema_1A	91..546	CDD:200498	182/473 (38%)
		PSI	545..>579	CDD:214655	17/33 (52%)
smp-1	NP_001379344.1	Sema_1A	49..497	CDD:200498	182/472 (39%)
		PSI	496..547	CDD:214655	24/55 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167824
Domainoid	1	1.000	324	1.000	Domainoid score	I645
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H122327
Inparanoid	1	1.050	389	1.000	Inparanoid score	I1142
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28691
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14671
orthoMCL	1	0.900	-	-		OOG6_101616
Panther	1	1.100	-	-	LDO	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X415
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.900