Protein Alignment Sema1a and AgaP_AGAP006636

DIOPT Version :9

• Sequence 1: NP_001260265.1
• Gene: Sema1a / 34192
• FlyBaseID: FBgn0011259
• Length: 1131
• Species: Drosophila melanogaster
• Sequence 2: XP_316667.4
• Gene: AgaP_AGAP006636 / 1277222
• VectorBaseID: AGAP006636
• Length: 679
• Species: Anopheles gambiae
• Alignment Length: 683
• Identity: 230/683 - (33%)
• Similarity: 334/683 - (48%)
• Gaps: 120/683 - (17%)

  Fly   102 KDGNSLLIGARNTVFNLSIHDL----VEQQRLVWTSPEDDTKMCLVKGKDEE-ACQNYIRIMVVP 161
            :|.::|.:||.|.|:.|::.::    .|:..::......|.:.|:.:||.|. .|:|:||::...
Mosquito    41 EDRDTLYVGAMNRVYRLNLKNISMTSCEKDSMLLDPTGADIRNCVSRGKSEMFDCKNHIRVIQPM 105

  Fly   162 SPG-RLFVCGTNSFRP-----MCNTYIISDSNYTLEATKNGQAVCPYDPRHNSTSVLADN----- 215
            ..| ||::||||:..|     ..|...:..|.| :.....|.|.|||||..|||::....
Mosquito   106 DNGTRLYICGTNAHSPKDVVIFRNLTHLPRSEY-VPGVGLGVAKCPYDPIDNSTAIYVHEGNPGG 169

  Fly   216 --ELYSGTVADFSGSDPIIYREPL-------------QTEQYDSLSLNAPNFVSSFTQGDFVYFF 265
              .|||||.|:|:.:|.:|:|..|             :|.:|||..|:.||||.||..|::||||
Mosquito   170 LPALYSGTNAEFTKADTVIFRADLYEMSSGKKMYNFKRTLKYDSKWLDKPNFVGSFDIGEYVYFF 234

  Fly   266 FRETAVEFINCGKAIYSRVARVCKWDKGGPHRFRNRWTSFLKSRLNCSIPGDYPFYFNEIQSASN 330
            |||.|||:||||||:|||||||||.|.||.:.....|.::||:||||||.|::||||||||..
Mosquito   235 FREIAVEYINCGKAVYSRVARVCKKDTGGKNILNQNWATYLKARLNCSISGEFPFYFNEIQDV-- 297

  Fly   331 LVEGQYGSMSSKL-IYGVFNTPSNSIPGSAVCAFALQDIADTFEGQFKEQTGINSNWLPVNNAKV 394
                 |...:.|. .|..|.|.:|.:.|||||:|:|.:|...|.|:||||...||.||||.::|:
Mosquito   298 -----YQMPTDKTKFYATFTTSTNGLVGSAVCSFSLGEIHSAFAGKFKEQATSNSAWLPVMSSKI 357

  Fly   395 PDPRPGSCHNDSRALPDPTLNFIKTHSLMDENVPAFFSQPILVRTSTIYRFTQIAVDAQIKTPGG 459
            |:||||:|.:|:..|||..||||::|.|||..|...:..|:..:...|  .|::.||........
Mosquito   358 PEPRPGTCVDDTTTLPDAVLNFIRSHPLMDRAVTHDYGNPVFYKRDLI--LTKLVVDKITIDILN 420

  Fly   460 KTYDVIFVGTDHGKIIKSVN-AESADSADKVTSVVIEEIDVLTKSEPIRNLEIVRTMQYDQPKDG 523
            :.|.|.::.|:.|:|.|.|. .....|..|:..:    .|| ..:|||   :::|..|..:
Mosquito   421 QEYLVYYLATNEGRIYKVVQYFHDGQSRAKLLDI----FDV-APNEPI---QVMRLSQRYK---- 473

  Fly   524 SYDDGKLIIVTDSQVVAIQLHRCHNDKITSCSECVALQDPYCAWDKIAGKCRSHGAPRWLEENYF 588
                 .|.|.|||::..|.|..| |.:..||..||  |||||.||:.:|.||.:       :..|
Mosquito   474 -----SLYIGTDSRIKQIDLVMC-NRRYDSCYRCV--QDPYCGWDRDSGSCRPY-------QLGF 523

  Fly   589 YQNVATGQHAACPSGKINSKDANAGEQK------------GFRNDMDLLDSR-----RQSKDQ-- 634
            .|:|.......|        |.|...:|            .|....::|..:     ..||::
Mosquito   524 LQDVGNRTSDIC--------DTNVMRKKIIVTFGQSVHLGCFARVPEILKYQPVTWYHHSKERGR 580

  Fly   635 -EIIDNIDKNFEGPQISADIINAQYTVETLVMAVLAGSI---FSLLVGFFTGYFCGRRC---HKD 692
             |:..::.|:.|..:....:|.............|.||:   |||:|.       ..||   .|.
Mosquito   581 YEVRYSVTKHIETSEGGLVVIAINEADSGRYDCYLGGSLLCSFSLVVD-------AHRCTAPSKG 638

  Fly   693 EDDNLPYPDTEYEY---------FEQRQNVNSF 716
            .|....|.|..:|:         :|.:|:|..|
Mosquito   639 NDYQKIYSDWCHEFERYKSALKRWEAKQSVGFF 671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1a	NP_001260265.1	Sema_1A	91..546	CDD:200498	181/476 (38%)
		PSI	545..>579	CDD:214655	16/33 (48%)
AgaP_AGAP006636	XP_316667.4	Sema_2A	33..489	CDD:200499	180/474 (38%)
		PSI	493..>516	CDD:279745	12/24 (50%)
		Ig	542..630	CDD:299845	16/94 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D153798at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820