Protein Alignment Sema1a and AgaP_AGAP005742

DIOPT Version :9

• Sequence 1: NP_001260265.1
• Gene: Sema1a / 34192
• FlyBaseID: FBgn0011259
• Length: 1131
• Species: Drosophila melanogaster
• Sequence 2: XP_001688723.1
• Gene: AgaP_AGAP005742 / 1276412
• VectorBaseID: AGAP005742
• Length: 769
• Species: Anopheles gambiae
• Alignment Length: 657
• Identity: 283/657 - (43%)
• Similarity: 394/657 - (59%)
• Gaps: 78/657 - (11%)

  Fly    73 PKLYVELGPEDVLKFVGNESVVDHFKLVTKDGNSLLIGARNTVFNLSIHDLVE--QQRLVWTSPE 135
            ||:.: :|...|..|.||.:  |:|||:..:...:||||||.|:|:||..|||  .||:.|.|.:
Mosquito    14 PKIAI-VGNATVPSFFGNST--DYFKLLDANEQYILIGARNAVYNISIDRLVELPGQRISWPSSD 75

  Fly   136 DDTKMCLVKGKDEEACQNYIRIMVVPSPGRLFVCGTNSFRPMCNTYIISDSNYTLEATKN---GQ 197
            ...::|.:|||.|:.||||||:....:..|:.|||||||:|:|..|.:...|.:|....|   .|
Mosquito    76 AHRELCTLKGKHEQDCQNYIRVFARINANRIMVCGTNSFKPLCRYYNVLPGNGSLVYDNNELEAQ 140

  Fly   198 AVCPYDPRHNSTSVLADNELYSGTVADFSGSDPIIYREPLQTEQYDSLSLNAPNFVSSFTQGDFV 262
            ..|||:|:||||.|..|.:|||.|||||||:|.:|||||.:|||:||..||.|.|||:.....:|
Mosquito   141 GRCPYNPQHNSTYVYTDGQLYSATVADFSGADALIYREPQRTEQFDSKQLNQPAFVSAIEYNGYV 205

  Fly   263 YFFFRETAVEFINCGKAIYSRVARVCKWDKGGPHRFRNRWTSFLKSRLNCSIPGDYPFYFNEIQS 327
            .||:||.|:|::||||||||||:||||.|||||:.|:::||||||:||||||||:|||||:|:|:
Mosquito   206 MFFYREVAMEYMNCGKAIYSRVSRVCKNDKGGPYPFQDKWTSFLKARLNCSIPGEYPFYFDELQA 270

  Fly   328 ASNLVEGQYGSMSSKLIYGVFNTPSNSIPGSAVCAFALQDIADTFEGQFKEQTGINSNWLPVNNA 392
            .:|.:.|.||.:.:|:|||:..||.|:|.|||||||:::||.:.|||.||.|..|:||||.|..:
Mosquito   271 TTNAISGTYGGVRNKIIYGIMTTPENAIGGSAVCAFSVEDIMEAFEGPFKAQRDIHSNWLQVPPS 335

  Fly   393 KVPDPRPGSCHNDSRALPDPTLNFIKTHSLMDENVPAFFSQPILVRTSTIYRFTQIAVDAQIKTP 457
            .||:||||.|.:|||.||...:||:||::|||.:||:..|:|:..|.|..||.:.||||.|:|..
Mosquito   336 AVPEPRPGKCVDDSRTLPKALVNFVKTNNLMDSSVPSVHSRPVFTRVSLYYRLSAIAVDPQVKAL 400

  Fly   458 GGKTYDVIFVGTDHGKIIKSVNAESADSADKVTSVVIEEIDVLTKSEPIRNLEIVRTMQYDQPKD 522
            .|:.||||||||:.||:||.||..||:::|.|.:|||.|.........|..:.|
Mosquito   401 DGQRYDVIFVGTNDGKVIKFVNILSANTSDDVRTVVISETQAFPPGTKINEMTI----------- 454

  Fly   523 GSYDDGKLIIVTDSQVVAIQLHRCHNDKITSCSECVALQDPYCAWDKIAGKCR------SHGAPR 581
             |..:..||:::..:::::.||.|:.....:|.:|:.|||||||||.:...|:      :.|||
Mosquito   455 -SKKNAALIVISSGKIISLPLHTCNEHSFKTCRKCLDLQDPYCAWDDLNRDCKPIDEVHASGAP- 517

  Fly   582 WLEENYFYQNVATGQHAACPSGKINSK--------------------DANAGEQKGFRNDMDLLD 626
               .:.|||.: .|:..    |:|..|                    |.:...:|..::    .|
Mosquito   518 ---IDQFYQRL-DGERI----GEICRKYDHQEPTVHTYEDNDVYTRVDGSGAVEKPDKS----FD 570

  Fly   627 SRR-----------QSKDQEIIDN--IDKNFEGPQISADIINA-QY--TVETLV-MAVLAG--SI 672
            .|.           .|...|.|||  ...:.||.:.:..|||. ||  ..:|.| ..||:.  ::
Mosquito   571 QRNVLIVHANHGTVSSVGPEDIDNEISMSSVEGDEQTNRIINTLQYQPKPDTFVKQNVLSATPNL 635

  Fly   673 FSLLVGF 679
            .|||:||
Mosquito   636 ISLLLGF 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1a	NP_001260265.1	Sema_1A	91..546	CDD:200498	228/459 (50%)
		PSI	545..>579	CDD:214655	13/39 (33%)
AgaP_AGAP005742	XP_001688723.1	Sema_1A	29..477	CDD:200498	230/461 (50%)
		PSI	480..>505	CDD:214655	11/24 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28691
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000892
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X415
TreeFam	0	0.000	Not matched by this tool.
	4	3.920