Protein Alignment Sema1a and Sema3d

DIOPT Version :9

• Sequence 1: NP_001260265.1
• Gene: Sema1a / 34192
• FlyBaseID: FBgn0011259
• Length: 1131
• Species: Drosophila melanogaster
• Sequence 2: NP_083158.3
• Gene: Sema3d / 108151
• MGIID: 1860118
• Length: 777
• Species: Mus musculus
• Alignment Length: 642
• Identity: 201/642 - (31%)
• Similarity: 324/642 - (50%)
• Gaps: 99/642 - (15%)

  Fly    47 YGWMQVFLLLTVLVIGNQSAWQENIRPKLYVELGPEDVL------KFVGNESVVDHFK--LVTKD 103
            :.||  .|::|||.:......::|| |:|  :|..:|:|      .|:|:...:| |:  |:.::
Mouse    20 HAWM--MLIMTVLFLPVTETSKQNI-PRL--KLTYKDLLLSNTCIPFLGSSEGLD-FQTLLLDEE 78

  Fly   104 GNSLLIGARNTVFNLSIHDLVEQ-QRLVWTSPEDDTKMCLVKGKDEEA-CQNYIRIMVVPSPGRL 166
            ...||:||::.||.||:.||.:. :::.|.:.::..::|.:.|||..| |.|:||::...:...:
Mouse    79 RGILLLGAKDHVFLLSLVDLNKNFKKIYWPAAKERVELCKLAGKDANAECANFIRVLQPYNKTHV 143

  Fly   167 FVCGTNSFRPMCNTYIISDSN-----YTLEA--TKNGQAVCPYDPRHNSTSVLADNELYSGTVAD 224
            :||||.:|.|:|. ||...:|     :.|:.  .::|:..||:||:....||:.|..|||||.:|
Mouse   144 YVCGTGAFHPLCG-YIDLGANKEELIFKLDTHNLESGRLKCPFDPQQPFASVMTDEHLYSGTASD 207

  Fly   225 FSGSDPIIYR--------EPLQTEQYDSLSLNAPNFVSSF-------TQGDFVYFFFRETAVEFI 274
            |.|.|....|        ..::|:..:...||...|:.:|       ...|.:||||||::.|..
Mouse   208 FLGKDTAFTRSLGLMQDHHSIRTDISEHHWLNGAKFIGTFPIPDTYNPDDDKIYFFFRESSQEGS 272

  Fly   275 NCGKAIYSRVARVCKWDKGGPHRFRNRWTSFLKSRLNCSIPGD--YPFYFNEIQSASNLVEGQYG 337
            ...::|.|||.||||.|.||.....|:||:|||:||.|||||.  ...:|:|:|....|   ...
Mouse   273 TSDRSILSRVGRVCKNDVGGQRSLINKWTTFLKARLICSIPGSDGADTHFDELQDIYLL---PTR 334

  Fly   338 SMSSKLIYGVFNTPSNSIPGSAVCAFALQDIADTFEGQFKEQTGINSNWLPVNNAKVPDPRPGSC 402
            ...:.::||||.|.|:...|||||.:::.||...|.|.:..:...:..|:.. :.::|.||||:|
Mouse   335 DERNPVVYGVFTTTSSIFKGSAVCVYSMADIRAVFNGPYAHKESADHRWVQY-DGRIPYPRPGTC 398

  Fly   403 HN--------DSRALPDPTLNFIKTHSLMDENVPAFFSQPILVRTSTIYRFTQIAVDAQIKTPGG 459
            .:        .:|..||..::||:.|.:|.::|......|...|.:..||.|||.||..:...|
Mouse   399 PSKTYDPLIKSTRDFPDDVISFIRRHPVMYKSVYPVAGAPTFKRINVDYRLTQIVVDHVVAEDG- 462

  Fly   460 KTYDVIFVGTDHGKIIKSVNAESADSADK--VTSVVIEEIDVLTKSEPIRNLEIVRTMQYDQPKD 522
             .|||:|:|||.|.::|.|:.    |.:|  :..||:||:.|......|.|:|:  :::..|...
Mouse   463 -QYDVMFLGTDIGTVLKVVSI----SKEKWNMEEVVLEELQVFKHPTAILNMEL--SLKQQQLYV 520

  Fly   523 GSYDDGKLIIVTDSQVVAIQLHRCHNDKITSCSECVALQDPYCAWDKIAGKCRSHGAPRWLEENY 587
            ||:|.          :|.:.|||| :....:|::|...:|||||||   |...|..||
Mouse   521 GSWDG----------LVQLSLHRC-DTYGKACADCCLARDPYCAWD---GNACSRYAP------- 564

  Fly   588 FYQNVATGQHAACPSGKINSKDANAGEQKGFRNDMDLLDS-RRQSKDQEIIDNIDKN 643
                  |.:..|      ..:|...|:.  .....|:.|| ..::.|:::|..|:.|
Mouse   565 ------TSKRRA------RRQDVKYGDP--ITQCWDIEDSISHETADEKVIFGIEFN 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1a	NP_001260265.1	Sema_1A	91..546	CDD:200498	160/492 (33%)
		PSI	545..>579	CDD:214655	13/33 (39%)
Sema3d	NP_083158.3	Sema_3D	61..534	CDD:200513	162/496 (33%)
		PSI	533..570	CDD:214655	16/53 (30%)
		Ig_Semaphorin_classIII	596..686	CDD:143279	4/12 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	740..777

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D153798at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920