Protein Alignment Sema1a and sema4gb

DIOPT Version :9

• Sequence 1: NP_001260265.1
• Gene: Sema1a / 34192
• FlyBaseID: FBgn0011259
• Length: 1131
• Species: Drosophila melanogaster
• Sequence 2: XP_003199679.2
• Gene: sema4gb / 100534852
• ZFINID: ZDB-GENE-111117-1
• Length: 881
• Species: Danio rerio
• Alignment Length: 1097
• Identity: 272/1097 - (24%)
• Similarity: 413/1097 - (37%)
• Gaps: 349/1097 - (31%)

  Fly    55 LLTVLVIGN--QSAWQENIRPKLYVELGPEDVLKFVG-------NESVVDHFKLVTKDGNSLL-I 109
            :|.::::|.  ...|.....|.|.:::.|...::..|       ..:.:::..|:.:||..:| :
Zfish     6 MLNLILVGYLIPVIWCFPFGPVLDMDVTPRTTVRVNGLLGCNHFQGAALNYSSLLLEDGPGVLYV 70

  Fly   110 GARNTVFNL---SIHDLVEQQRLVWTSPEDDTKMCLVKGKDEEA-CQNYIRIMVVPSPGRLFVCG 170
            |||..::.|   :|.|......|.|.:..|..:.||.|||:.:. |.|::|.:...:...|:.||
Zfish    71 GAREAIYKLDTANISDTNNSLTLEWAASADQKRQCLSKGKNNQTECYNHVRFLDRYNDTHLYTCG 135

  Fly   171 TNSFRPMCNTYIISDSNYTLEATKNGQAVCPYDPRHNSTSVLADNELYSGTVADFSGSDPIIYRE 235
            |::|||.| .| |..:.:|....:.|:..|||||....|..:.|.|:||.:..:|.....|....
Zfish   136 THAFRPRC-AY-IDVARFTFVRFEEGKEKCPYDPTKGYTGFIIDGEMYSASQYEFRNIADIRRNF 198

  Fly   236 P---LQTEQYDSLSLNAPNFV----------SSFTQGDFVYFFFRETAVEFINCGKAIYS----- 282
            |   |:.:...:..|...:||          ||....|.:||||.|.     |.....||
Zfish   199 PFPNLRIDDSPTRWLLESDFVGSALLRESINSSIGDDDKLYFFFTER-----NTEPTAYSIQTKV 258

  Fly   283 -RVARVCKWDKGGPHRFRNRWTSFLKSRLNCSIPGDYPFYFNEIQSASNLVEGQYGSMSSKLIYG 346
             |||||||.|.||....:.:||||||:||.|:|| ||...||.::|.. :|||  .::...:.||
Zfish   259 ARVARVCKGDIGGQRTLQRKWTSFLKARLVCAIP-DYELQFNVLRSVF-VVEG--SNVHDSVFYG 319

  Fly   347 VFNTPSNSIPGSAVCAFALQDIADTFEGQFKEQTGINSNWLPVNNAKVPDPRPGSC----H---- 403
            :|.....::..||||.::|:||...|.|.|.|..  :|.|... ..||||||||||    |
Zfish   320 IFGLEWRNVKMSAVCRYSLKDIQTAFNGPFMELQ--DSKWREY-TGKVPDPRPGSCITDEHRGKL 381

  Fly   404 -NDSRALPDPTLNFIKTHSLMDENVPAFFSQPILVRTSTIYRFTQIAVDAQIKTPGGKTYDVIFV 467
             |.||.|||.||||::.|.||...:.....:|:|::.:..|  |:|.|. |::...|:|||::|:
Zfish   382 INSSRDLPDNTLNFVRRHPLMSTQIQPVEGRPLLLQKAADY--TKIIVQ-QVEGLDGRTYDMLFI 443

  Fly   468 GTDHGKIIKSVNAESADSADKVTSVVIEEIDVLTKSEPIRNLEIVRTMQYDQPKDGSYDDGKLII 532
            |||.|.:.::|..     .|:|.  :|||:.:..:.:||.|:.|      .|.::..|..|.
Zfish   444 GTDEGWLQRAVKI-----IDRVH--IIEELQLFQEKQPIINMVI------SQKQNSIYVSGA--- 492

  Fly   533 VTDSQVVAIQLHRCHNDKITSCSECVALQDPYCAWDKIAGKCRSHGAPRWLEENYFYQNVATGQH 597
               |.:|.:.|..|  ::.|||.:||..:||.|.||
Zfish   493 ---SGLVQVPLSSC--ERYTSCYDCVFARDPLCGWD----------------------------- 523

  Fly   598 AACPSGKINSKDANAGEQKGFRNDMDLLDSRRQSKDQEIIDNIDKNFEGPQISADIINAQYTVET 662
                 |::.::.|:...:.....|:.:  .||.      ..||                  |.:.
Zfish   524 -----GRMCAEIASYANRSSLVQDIQM--GRRG------CSNI------------------TSDG 557

  Fly   663 LVM----AVLAGSIFSLLVGFFTGYFCGRRCHKDEDDNLPYPDTEYEYFEQRQNVNSFPSSCRIQ 723
            .||    ||:||                       ||.|                    ..|.|:
Zfish   558 FVMHRTRAVMAG-----------------------DDVL--------------------LQCEIR 579

  Fly   724 QEPKLLPQVEEVTYAEPVLLPQPPPPNKMHSPKNTLRKPPMHQMHQGPNSETLFQFQPDGYNTQQ 788
                                      :.:.:|:.||            ||:.|     .||....
Zfish   580 --------------------------SNLATPQWTL------------NSQEL-----KGYGVDS 601

  Fly   789 SYR-GRDNFGTLRSHQVMGDNYRRGDGFSTTRSVKKAVNNTNTRNRSLGRARRQPPRHGIVTQHR 852
            .|| |.|....:.:......:||   .::...||...:.:      .:.|.:..||    ...|.
Zfish   602 GYRTGTDGLLIIGAQNQQSGHYR---CYAVENSVWVPIRS------YIVRVQPVPP----PASHL 653

  Fly   853 SNSPQQQQQQ----SQQPHSSSGSSPVMSNSSSSPAPPSSSPSPQESPKNCSYIYRDXL-----I 908
            |.||....:.    :..|..|..|.||....|..|||..|.|..| :.|:...:|...:     :
Zfish   654 SGSPTALPESFFTTTTVPTPSPSSGPVEQLLSPPPAPLPSDPEFQ-TYKHMEAMYISLVAVLGGL 717

  Fly   909 CNTKSMPLIQ----AQSTHAQPHPQSHPHPLPPPGPTTPPAQPRA--------RSPMIGRTYAKS 961
            |...::.|:.    ||::....:.|.      ....|||..:.|:        .|...|||..:|
Zfish   718 CLVLTVLLLYVSFCAQNSLDAKYSQQ------ALSITTPTERKRSSHFELKTISSHCNGRTEGRS 776

  Fly   962 ---------MPVTPVQPQSPLAETPSYELYERHSDAATFHFGDEDDDDDDEHDHEDTSSLAMITP 1017
                     :.:.|:..|:    |||.|
Zfish   777 RAMSRDEEFLQIVPLDIQT----TPSEE------------------------------------- 800

  Fly  1018 PPPYDTPHLIASPPLPPPRRFRFGNRELFSMSPAGGGATPTASAGQRGSSAITPTKL 1074
            |||  .|.|...||||                         ||....|.||..|:.|
Zfish   801 PPP--APPLPMPPPLP-------------------------ASEYANGLSATLPSVL 830

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1a	NP_001260265.1	Sema_1A	91..546	CDD:200498	162/487 (33%)
		PSI	545..>579	CDD:214655	11/33 (33%)
sema4gb	XP_003199679.2	Sema_4G	47..501	CDD:200523	161/489 (33%)
		PSI	502..>541	CDD:279745	13/74 (18%)
		Ig	561..646	CDD:299845	26/179 (15%)
		IG_like	566..643	CDD:214653	24/171 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910