DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sema1a and dok2

DIOPT Version :9

Sequence 1:	NP_001260265.1	Gene:	Sema1a / 34192	FlyBaseID:	FBgn0011259	Length:	1131	Species:	Drosophila melanogaster
Sequence 2:	XP_002932742.2	Gene:	dok2 / 100487659	XenbaseID:	XB-GENE-982227	Length:	416	Species:	Xenopus tropicalis

Alignment Length:	178	Identity:	35/178 - (19%)
Similarity:	58/178 - (32%)	Gaps:	51/178 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   854 NSPQQQQQQSQQPHSSSGSSPVMSNSSSSPAPPSSSPSPQESPKNCSYIYRDXLICNTKSMPLIQ 918
            |:.::|..:...|.|...::.::..     .|..|.|.||.|               ....|.||
Frog   241 NNKKEQVSEEAPPGSRKRTTSLVPK-----GPAVSGPCPQSS---------------VVGKPSIQ 285

  Fly   919 AQSTHAQPHPQSHPHPLPPP-----GPTTPPAQPRARSPMIGRTYAKSMPVTPVQPQSPLAETPS 978
            .:|.:|.|..:...:.|...     ||..|....|.::...|:  |:.:...|..|.:|:.:.|.
Frog   286 EESEYAVPFDKVAQNLLATGFGGLLGPHIPQQDKRPKARPAGQ--AEPIYDEPGTPHNPVYDEPE 348

  Fly   979 YELYERHSDAATFHFGDEDDDDDDEHDHEDTSSLAMITPPPPYDTPHL 1026
            ....|.....||           |.|:             ..|:.|:|
Frog   349 VIRSEAWKTQAT-----------DAHE-------------TGYEFPYL 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sema1a	NP_001260265.1	Sema_1A	91..546	CDD:200498
Sema1a	NP_001260265.1	PSI	545..>579	CDD:214655
dok2	XP_002932742.2	PH-like	7..115	CDD:388408
dok2	XP_002932742.2	PH-like	150..244	CDD:388408	1/2 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010