Protein Alignment Sema1a and sema4d

DIOPT Version :9

• Sequence 1: NP_001260265.1
• Gene: Sema1a / 34192
• FlyBaseID: FBgn0011259
• Length: 1131
• Species: Drosophila melanogaster
• Sequence 2: XP_012814281.1
• Gene: sema4d / 100038178
• XenbaseID: XB-GENE-492763
• Length: 852
• Species: Xenopus tropicalis
• Alignment Length: 620
• Identity: 193/620 - (31%)
• Similarity: 309/620 - (49%)
• Gaps: 87/620 - (14%)

  Fly    78 ELGPEDVLKFVGNESVVDHFK----------LVTKDGNSLLIGARNTVFNLSIHDLVEQ-QRLVW 131
            |.||...:.:...|:.:.||.          |::::.:.|.:|||..:|.:|..::.|: ....|
 Frog    22 EFGPAPRITWHLKETNLMHFHVSGISNYSTLLLSEEKDVLYVGAREAIFAVSSLNVAEKLHEAYW 86

  Fly   132 TSPEDDTKMCLVKGKDEEA-CQNYIRIMVVPSPGRLFVCGTNSFRPMCNTYIISDSNYTLEATKN 195
            ...::....|..|||.::. |.||||::...:...|:|||||:|:|.|:...::|.. .|...::
 Frog    87 KVSDEKNNECAWKGKSKQTECLNYIRVIQPLNDKTLYVCGTNAFQPTCDYLNLTDFR-LLGRNED 150

  Fly   196 GQAVCPYDPRHNSTSVLADNELYSGTVADFSGSDPIIYREPLQTE---QYDSLSLNAPNFV---- 253
            |:..||:||..:..||:.|.||||||..:|.||:|||:|...|::   :|....||.|:||
 Frog   151 GKGRCPFDPAQSYISVMVDGELYSGTSFNFLGSEPIIFRHSSQSQLRTEYAVPWLNEPSFVYADV 215

  Fly   254 ----SSFTQG--DFVYFFFRETAVEFINCGKAIYSRVARVCKWDKGGPHRFRNRWTSFLKSRLNC 312
                ::..:|  |.|||||.|.:||:....|.:..|||||||.|:||....:.:||||||::|.|
 Frog   216 IRAPANNPEGDDDKVYFFFTEVSVEYEFFSKLLIPRVARVCKGDQGGLRTLQKKWTSFLKAKLIC 280

  Fly   313 SIPGDYPFYFNEIQSASNLVEGQYGSMSSKLIYGVFNTPSNSIPGSAVCAFALQDIADTF-EGQF 376
            . ..:....||.:.....|   ::...|...|||||.:..|::..|||||:.:..:.:.| :|::
 Frog   281 H-SSENNLIFNVVSDVFIL---KHSDSSEPKIYGVFTSHLNNVGLSAVCAYNVSTVEEVFAKGKY 341

  Fly   377 KEQTGI---NSNWLPVNNAKVPDPRPGSC-HNDSRA--------LPDPTLNFIKTHSLMDENVPA 429
            .....:   |:.|:.. |.:||.||||:| :|::||        |||.||.|:|.|.|||::|..
 Frog   342 MHSATVEQSNTKWVRY-NGEVPKPRPGACINNEARAMNYTSSLNLPDMTLQFVKDHPLMDDSVSP 405

  Fly   430 FFSQPILVRTSTIYRFTQIAVDAQIKTPGGKTYDVIFVGTDHGKIIKSVNAESADSADKVTSVVI 494
            ..::|.||....||  |||.|| ::|...|.:||::|:.||.|.:.|:|   |.|:..:    :|
 Frog   406 VGNKPKLVLRDVIY--TQIVVD-RVKALDGNSYDIMFLSTDKGILHKAV---SQDAEMR----II 460

  Fly   495 EEIDVLTKSEPIRNLEIVRTMQYDQPKDGSYDDGKLIIVTDSQVVAIQLHRCHNDKITSCSECVA 559
            |||.:....:|::.|.:            |..:||..|...|....:|......:|.|||.:|:.
 Frog   461 EEIVLFPHLQPVQTLLL------------SNKEGKRFIYAGSNTGVVQSPLAFCEKFTSCKDCIL 513

  Fly   560 LQDPYCAWDKIAGKCRSHGAPRWLEENYFYQNVATGQHAACPSGKINSKDANAGEQKGF------ 618
            .:||||||..:...|          .|....:.|.|......:|..:....:|..||..
 Frog   514 TRDPYCAWHPVKRSC----------VNILQDSTADGSLIQKLNGDASQCPDSAEIQKSMKHTVKS 568

  Fly   619 RNDMDLLDSRRQSKDQEIIDNIDKNFEGPQISADI 653
            |:.::|..|::..     :.|:...|....:.|::
 Frog   569 RSTVELKCSQKSK-----LANLVWQFSNKTLKAEL 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1a	NP_001260265.1	Sema_1A	91..546	CDD:200498	165/492 (34%)
		PSI	545..>579	CDD:214655	12/33 (36%)
sema4d	XP_012814281.1	Sema_4D	30..500	CDD:200520	165/497 (33%)
		PSI	502..>529	CDD:214655	12/36 (33%)
		Ig	561..645	CDD:386229	6/43 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010