Protein Alignment IDH3A and CG5028

DIOPT Version :9

• Sequence 1: NP_005521.1
• Gene: IDH3A / 3419
• HGNCID: 5384
• Length: 366
• Species: Homo sapiens
• Sequence 2: NP_001097922.1
• Gene: CG5028 / 43102
• FlyBaseID: FBgn0039358
• Length: 402
• Species: Drosophila melanogaster
• Alignment Length: 342
• Identity: 133/342 - (38%)
• Similarity: 201/342 - (58%)
• Gaps: 22/342 - (6%)

Human    29 GGVQTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPS-EAKESMD--- 89
            ||...||::||.|||||:...|.:||....|||.:|..::.           || |..:.:|
  Fly    55 GGRHAVTMLPGGGIGPELMGYVREIFRYCGAPIDFEVIDID-----------PSTEGNDDLDYAI 108

Human    90 ----KNKMGLKGPLKTPI-AAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENT 149
                :|.:.|||.::|.. :....|.|:.:|...|||.||..|.|..|....:.|:::|.||:||
  Fly   109 TSIKRNGVALKGNIETKSQSLTEVSRNVAIRNELDLYVNVVHCKSYPGIPARHHDIDVVLIRQNT 173

Human   150 EGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQK 214
            :|||:.:||..|.|:|:|:|::|...::|:|.:|||:||.|:|..||.:||||||::||||||:.
  Fly   174 DGEYAMLEHESVPGIVESMKVVTVENAERVARYAFEFARQNNRKKVTTIHKANIMKLSDGLFLEV 238

Human   215 CREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIG 279
            ...|.:...:::.|.|.:|..|:..|.:|.||||:.|.||||.|:|::..||:||.|:....|.|
  Fly   239 ANRVHKDYPELEHNNMIIDNTCMQSVSNPHQFDVMNMTNLYGTIVSNVLCGLMGGAGLISGRNYG 303

Human   280 ANGVAIFE-SVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTK 343
             :..|||| ....|...||||::|||.|::.:::.||.|:|..:||..|:.|.:.||.:....|.
  Fly   304 -DHYAIFEPGTRNTGTAIAGKNIANPVAMISASIDMLNHLGHKEHANVIQEAVYQTIVNDAIRTP 367

Human   344 DLGGNAKCSDFTEEICR 360
            |:||....:|..|.|.:
  Fly   368 DIGGTNSSTDVVENILK 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IDH3A	NP_005521.1	mito_nad_idh	29..362	CDD:272942	133/342 (39%)
CG5028	NP_001097922.1	mito_nad_idh	55..386	CDD:272942	133/342 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0473
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53770
OrthoDB	1	1.010	-	-		D325037at33208
OrthoFinder	1	1.000	-	-		FOG0000244
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X402
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.830