Protein Alignment IDH3A and idh3a

DIOPT Version :10

• Sequence 1: NP_005521.1
• Gene: IDH3A / 3419
• HGNCID: 5384
• Length: 366
• Species: Homo sapiens
• Sequence 2: NP_989352.1
• Gene: idh3a / 394979
• XenbaseID: XB-GENE-943186
• Length: 366
• Species: Xenopus tropicalis
• Alignment Length: 366
• Identity: 315/366 - (86%)
• Similarity: 337/366 - (92%)
• Gaps: 0/366 - (0%)

Human     1 MAGPAWISKVSRLLGAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEE 65
            |||.||.|.:||:.||...|:...|..:..|||||||||||||||||.||||||:.||||:||||
 Frog     1 MAGSAWRSLISRVAGALTAPEYGARQLSNHVQTVTLIPGDGIGPEISTAVMKIFETAKAPVQWEE 65

Human    66 RNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSI 130
            ||||||:|||||||||.||||||||||||||||||||||||||||||||||||||||||||||||
 Frog    66 RNVTAIKGPGGKWMIPPEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSI 130

Human   131 EGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNV 195
            |||:||||||::|||||||||||||||||||||||||||||||.||.|||:|||||||||.||.|
 Frog   131 EGYRTPYTDVDLVTIRENTEGEYSGIEHVIVDGVVQSIKLITEEASHRIAQFAFEYARNNQRSTV 195

Human   196 TAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILS 260
            |||||||||||||||||:|||||||:.|||||||||||||||||||||:||||||||||||||||
 Frog   196 TAVHKANIMRMSDGLFLKKCREVAENFKDIKFNEMYLDTVCLNMVQDPTQFDVLVMPNLYGDILS 260

Human   261 DLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAA 325
            ||||||||||||||||||||||||||||||||||||||||:|||||||||||||||||||.:||.
 Frog   261 DLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDLANPTALLLSAVMMLRHMGLHEHAR 325

Human   326 RIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD 366
            :||.|||.|||.||:||||||||:|||:||.|||||::|.|
 Frog   326 KIENACFETIKSGKALTKDLGGNSKCSEFTNEICRRIQDSD 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IDH3A	NP_005521.1	mito_nad_idh	29..362	CDD:272942	300/332 (90%)
idh3a	NP_989352.1	Iso_dh	31..362	CDD:444908	300/330 (91%)