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Protein Alignment Acer and Ace2

DIOPT Version :9

Sequence 1:	NP_001260258.1	Gene:	Acer / 34189	FlyBaseID:	FBgn0016122	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_001123985.1	Gene:	Ace2 / 70008	MGIID:	1917258	Length:	805	Species:	Mus musculus

Alignment Length:	623	Identity:	231/623 - (37%)
Similarity:	345/623 - (55%)	Gaps:	31/623 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VLLLVIMLWLPHGLSMGNSCSASVLEARRFFELENEQLRRRFHEEFLSGYNYNTNVTEANRQAMI 72
            :||.::.:.....|:..|        |:.|....|::.....::..|:.:|||||:||.|.|.|.
Mouse     7 LLLSLVAVTTAQSLTEEN--------AKTFLNNFNQEAEDLSYQSSLASWNYNTNITEENAQKMS 63

  Fly    73 EVYARNAELNKRLAQQIKSSDYVQSEDADIRRQAEHLSKLGASALNADDYLALQNAISSMQTNYA 137
            |..|:.:...:..::..:|....:.:...|:||.:.|.:.|:|||:||....|...:::|.|.|:
Mouse    64 EAAAKWSAFYEEQSKTAQSFSLQEIQTPIIKRQLQALQQSGSSALSADKNKQLNTILNTMSTIYS 128

  Fly   138 TATVCSYTNRSDCSLTLEPHIQERLSHSRDPAELAWYWREWHDKSGTPMRQNFAEYVRLTRKASQ 202
            |..||:..|..:| |.|||.:.|.::.|.|.....|.|..|..:.|..:|..:.|||.|..:.::
Mouse   129 TGKVCNPKNPQEC-LLLEPGLDEIMATSTDYNSRLWAWEGWRAEVGKQLRPLYEEYVVLKNEMAR 192

  Fly   203 LNGHRSYADYWVQFYEDP-----DFER-----QLDATFKQLLPFYRQLHGYVRFRLRQHYGPDVM 257
            .|.:..|.|||...||..     ::.|     .::.||.::.|.|..||.|||.:|...| |..:
Mouse   193 ANNYNDYGDYWRGDYEAEGADGYNYNRNQLIEDVERTFAEIKPLYEHLHAYVRRKLMDTY-PSYI 256

  Fly   258 PAEGNIPISLLGNMWGQSWNELLDLFTPYPEKPFVDVKAEMEKQGYTVQKLFELGDQFFQSLGMR 322
            ...|.:|..|||:|||:.|..|..|..|:.:||.:||...|..||:..:::|:..::||.|:|:.
Mouse   257 SPTGCLPAHLLGDMWGRFWTNLYPLTVPFAQKPNIDVTDAMMNQGWDAERIFQEAEKFFVSVGLP 321

  Fly   323 ALPPSFWNLSVLTRP-DDRHVVCHASAWDFYQDSDVRIKMCTEVDSHYFYVVHHELGHIQYYLQY 386
            .:...||..|:||.| |.|.||||.:|||. ...|.||||||:|....|...|||:|||||.:.|
Mouse   322 HMTQGFWANSMLTEPADGRKVVCHPTAWDL-GHGDFRIKMCTKVTMDNFLTAHHEMGHIQYDMAY 385

  Fly   387 EQQPAVYRGAPNPGFHEAVGDVIALSVMSAKHLKAIGLIENG-RLDEKSRINQLFKQALSKIVFL 450
            .:||.:.|...|.|||||||::::||..:.||||:|||:.:. :.|.::.||.|.||||:.:..|
Mouse   386 ARQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLPSDFQEDSETEINFLLKQALTIVGTL 450

  Fly   451 PFGYAVDKYRYAVFRNELDESQWNCGFWQMRSEFGGVEPPVFRTEKDFDPPAKYHIDADVEYLRY 515
            ||.|.::|:|:.|||.|:.:.||...:|:|:.|..||..|:...|...||.:.:|:..|..::||
Mouse   451 PFTYMLEKWRWMVFRGEIPKEQWMKKWWEMKREIVGVVEPLPHDETYCDPASLFHVSNDYSFIRY 515

  Fly   516 FAAHIFQFQFHKALCRKAGQYAPNNSRLTLDNCDIFGSKAAGRSLSQFLSKGNSRHWKEVLEEFT 580
            :...|:||||.:||| :|.:|  |.|   |..|||..|..||:.|.:.||.|||..|.:.||...
Mouse   516 YTRTIYQFQFQEALC-QAAKY--NGS---LHKCDISNSTEAGQKLLKMLSLGNSEPWTKALENVV 574

  Fly   581 GETEMDPAALLEYFEPLYQWLKQE--NSRLGVPLGWGP 616
            |...||...||.||:||:.|||::  ||.:|....|.|
Mouse   575 GARNMDVKPLLNYFQPLFDWLKEQNRNSFVGWNTEWSP 612

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.