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Protein Alignment Acer and Ace2

DIOPT Version :9

Sequence 1:	NP_001260258.1	Gene:	Acer / 34189	FlyBaseID:	FBgn0016122	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_001012006.1	Gene:	Ace2 / 302668	RGDID:	728890	Length:	805	Species:	Rattus norvegicus

Alignment Length:	624	Identity:	236/624 - (37%)
Similarity:	343/624 - (54%)	Gaps:	42/624 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 MGNSC-----SASVLEARRFFELENEQLRRRFHEE--------FLSGYNYNTNVTEANRQAMIEV 74
            |.:||     ..:|..|:...|.:.|....:|::|        .|:.:|||||:||.|.|.|.|.
  Rat     1 MSSSCWLLLSLVAVATAQSLIEEKAESFLNKFNQEAEDLSYQSSLASWNYNTNITEENAQKMNEA 65

  Fly    75 YARNA---ELNKRLAQQIKSSDYVQSEDADIRRQAEHLSKLGASALNADDYLALQNAISSMQTNY 136
            .|:.:   |...::||.....:.   ::|.|:||.:.|.:.|:|||:.|....|...:::|.|.|
  Rat    66 AAKWSAFYEEQSKIAQNFSLQEI---QNATIKRQLKALQQSGSSALSPDKNKQLNTILNTMSTIY 127

  Fly   137 ATATVCSYTNRSDCSLTLEPHIQERLSHSRDPAELAWYWREWHDKSGTPMRQNFAEYVRLTRKAS 201
            :|..||:..|..:|.| |||.:.|.::.|.|.....|.|..|..:.|..:|..:.|||.|..:.:
  Rat   128 STGKVCNSMNPQECFL-LEPGLDEIMATSTDYNRRLWAWEGWRAEVGKQLRPLYEEYVVLKNEMA 191

  Fly   202 QLNGHRSYADYWVQFYEDPDFE----------RQLDATFKQLLPFYRQLHGYVRFRLRQHYGPDV 256
            :.|.:..|.|||...||....|          ..::.|||::.|.|.|||.|||.:|.:.| |..
  Rat   192 RANNYEDYGDYWRGDYEAEGVEGYNYNRNQLIEDVENTFKEIKPLYEQLHAYVRTKLMEVY-PSY 255

  Fly   257 MPAEGNIPISLLGNMWGQSWNELLDLFTPYPEKPFVDVKAEMEKQGYTVQKLFELGDQFFQSLGM 321
            :...|.:|..|||:|||:.|..|..|.||:.:||.:||...|..|.:..:::|:..::||.|:|:
  Rat   256 ISPTGCLPAHLLGDMWGRFWTNLYPLTTPFLQKPNIDVTDAMVNQSWDAERIFKEAEKFFVSVGL 320

  Fly   322 RALPPSFWNLSVLTRP-DDRHVVCHASAWDFYQDSDVRIKMCTEVDSHYFYVVHHELGHIQYYLQ 385
            ..:.|.||..|:||.| |||.||||.:|||. ...|.||||||:|....|...|||:|||||.:.
  Rat   321 PQMTPGFWTNSMLTEPGDDRKVVCHPTAWDL-GHGDFRIKMCTKVTMDNFLTAHHEMGHIQYDMA 384

  Fly   386 YEQQPAVYRGAPNPGFHEAVGDVIALSVMSAKHLKAIGLI-ENGRLDEKSRINQLFKQALSKIVF 449
            |.:||.:.|...|.|||||||::::||..:.||||:|||: .|.:.|.::.||.|.||||:.:..
  Rat   385 YAKQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLPSNFQEDNETEINFLLKQALTIVGT 449

  Fly   450 LPFGYAVDKYRYAVFRNELDESQWNCGFWQMRSEFGGVEPPVFRTEKDFDPPAKYHIDADVEYLR 514
            |||.|.::|:|:.||::::...||...:|:|:.|..||..|:...|...||.:.:|:..|..::|
  Rat   450 LPFTYMLEKWRWMVFQDKIPREQWTKKWWEMKREIVGVVEPLPHDETYCDPASLFHVSNDYSFIR 514

  Fly   515 YFAAHIFQFQFHKALCRKAGQYAPNNSRLTLDNCDIFGSKAAGRSLSQFLSKGNSRHWKEVLEEF 579
            |:...|:||||.:|||:.|....|      |..|||..|..||:.|...||.|||..|...||..
  Rat   515 YYTRTIYQFQFQEALCQAAKHDGP------LHKCDISNSTEAGQKLLNMLSLGNSGPWTLALENV 573

  Fly   580 TGETEMDPAALLEYFEPLYQWLKQE--NSRLGVPLGWGP 616
            .|...||...||.||:||:.|||::  ||.:|....|.|
  Rat   574 VGSRNMDVKPLLNYFQPLFVWLKEQNRNSTVGWSTDWSP 612

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.