DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sgp and FAR4

DIOPT Version :9

Sequence 1:	NP_001260257.1	Gene:	Sgp / 34188	FlyBaseID:	FBgn0032055	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	NP_190040.3	Gene:	FAR4 / 823579	AraportID:	AT3G44540	Length:	493	Species:	Arabidopsis thaliana

Alignment Length:	533	Identity:	135/533 - (25%)
Similarity:	237/533 - (44%)	Gaps:	113/533 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQTDILQFYKDKSVFVTGGTGFLGKVIIEKLLR-STDVRRVYLLVRPKKNETVEGRFQA-WKDEP 63
            |.::.:||..||::.|||..|||.||.:||:|| ...|::::||:|...||:...||.: ..::.
plant     1 MDSNCIQFLHDKTILVTGVPGFLAKVFVEKILRIQPKVKKLFLLLRAADNESAMQRFHSEVLEKD 65

  Fly    64 VFKILLKA-KPEALKL-----VTPISGDCSEPGLGLSDGD-RRMVTADVQVIIHSAASIRFVEPL 121
            :|::|..| ..|.||.     |.||.||.|...||:...| .:.:..::.:|::.||:..|.|..
plant    66 LFRVLKNALGDENLKAFITEKVVPIPGDISVDNLGVKGSDLLQHMWNEIDIIVNVAATTNFDERY 130

  Fly   122 QRALNINTRATRLMIQLAKE-MKGLEAFVHISTAFSNCPSQHI--EERFY-PEHLTCPAAKVLE- 181
            ...|::||.....::..||: :|| :..:|:|||:.......:  |:.|: .|.|......|:|
plant   131 DVGLSVNTFGPLNVLNFAKKCVKG-QLLLHVSTAYVRGEKSGLLHEKTFHMGETLNGHRKLVIET 194

  Fly   182 -----------------FNETLSPDLLD-KMAPALMGKFPNTYTYTKALAEQVIQMEGQDLPICV 228
                             ..|.:|..:.| .|:.|.:..:||||.:||::.|.::....::|||.:
plant   195 EMELMKQKLKELQKQNCSEEEISQSMKDLGMSRAKLHGWPNTYVFTKSMGEMLLGNYRENLPIVI 259

  Fly   229 FRPAIILANFKEPMSGWIDNLHGVVALIYGNTYGILRLLYVNPKADAIIVPGDYCANVALASGWQ 293
            .||.:|.:.|.||..|||:.|..:.::|.....|.|:....:|.:...::|.|..||..:.:
plant   260 IRPTMITSTFSEPFPGWIEGLRTIDSVIVAYGKGRLKCFLADPNSVLDLIPVDMVANAMVTA--- 321

  Fly   294 VAKNSESRSSSQLAAKKPPPIYTLATTKSNSITFGKAVKLGIHH----------NHTIPVTK-TI 347
             |.....:..||       .:|.:.::..|.|||.:...|...:          ..:|.|:| ||
plant   322 -AAIHAGKLGSQ-------TVYHVGSSCKNPITFEQIHDLAASYFTKNPLVRRDGSSILVSKGTI 378

  Fly   348 WYPFAHFTTCPWLFKLGCIFYHLIPGFFFDLLLRIQGKKPILMRSYQKIHEVLLLLFP-FNGKTY 411
            ....|.|:           ||           :.::.|.|:.|.      .::.:::| :||..|
plant   379 LSTMAQFS-----------FY-----------MTLRYKLPLQML------RLIYVIYPWWNGNKY 415

  Fly   412 E-------------------------MDMNNTNQL---WDSMSPEDRSIFPFDMATLNWEEYFTR 448
            :                         .|..||.:|   ...::.|...:|.||..:::||:|.|.
plant   416 KDIDRKIKLAMRLVDLYRPYVLFKGIFDDTNTEKLRLKRKEINKEMYGLFEFDPKSIDWEDYMTT 480

  Fly   449 I-LSGMRVFLYKE 460
            | :.|:..::.|:
plant   481 IHIPGLITYVLKK 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sgp	NP_001260257.1	PLN02996	1..449	CDD:215538	132/519 (25%)
		FAR-N_SDR_e	12..333	CDD:187547	99/352 (28%)
		FAR_C	367..457	CDD:176924	23/119 (19%)
FAR4	NP_190040.3	PLN02996	1..492	CDD:215538	134/530 (25%)
		FAR-N_SDR_e	12..362	CDD:187547	100/361 (28%)
		Sterile	393..492	CDD:281068	21/104 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D815047at2759
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.970