Protein Alignment Sgp and Far1

DIOPT Version :10

• Sequence 1: NP_609241.1
• Gene: Sgp / 34188
• FlyBaseID: FBgn0032055
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_081655.2
• Gene: Far1 / 67420
• MGIID: 1914670
• Length: 515
• Species: Mus musculus
• Alignment Length: 509
• Identity: 166/509 - (32%)
• Similarity: 269/509 - (52%)
• Gaps: 30/509 - (5%)

  Fly     5 ILQFYKDKSVFVTGGTGFLGKVIIEKLLRSTD-VRRVYLLVRPKKNETVEGRFQAWKDEPVFKIL 68
            |.::|:.|::.:||.|||||||::||||||.. |..||:|||.|..:|.:.|.:......:|..|
Mouse     4 IPEYYEGKNILLTGATGFLGKVLLEKLLRSCPRVNSVYVLVRQKAGQTPQERVEEILSSKLFDRL 68

  Fly    69 LKAKPEALKLVTPISGDCSEPGLGLSDGDRRMVTADVQVIIHSAASIRFVEPLQRALNINTRATR 133
            ....|:..:.:..|:.:.::|.|.||:.|:.::.....||.|.||::||.|.|:.|:.:|..|||
Mouse    69 RDENPDFREKIIAINSELTQPKLALSEEDKEIIIDSTNVIFHCAATVRFNENLRDAVQLNVIATR 133

  Fly   134 LMIQLAKEMKGLEAFVHISTAFSNCPSQHIEERFYPEHLTCPAAKVLEFNETLSPDLLDKMAPAL 198
            .:|.||::||.||.|:|:|||::.|..:||:|..||..:  ...|:::..|.:...|::.:.|.|
Mouse   134 QLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPV--DPKKLIDSLEWMDDGLVNDITPKL 196

  Fly   199 MGKFPNTYTYTKALAEQVIQMEGQDLPICVFRPAIILANFKEPMSGWIDNLHGVVALIYGNTYGI 263
            :|..||||.|||||||.|:|.||..|.:.:.||:|:.|::|||..|||||.:|...|......||
Mouse   197 IGDRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKGI 261

  Fly   264 LRLLYVNPKADAIIVPGDYCANVALASGWQVAKNSESRSSSQLAAKKPPPI--YTLATTKSNSIT 326
            ||.:..:..|.|.:||.|...|.:||:.|....|            :|..|  |...|..:|...
Mouse   262 LRTMRASNNALADLVPVDVVVNTSLAAAWYSGVN------------RPRNIMVYNCTTGSTNPFH 314

  Fly   327 FGKAVKLGIHHNHTI------PVTKTIWYPFAHFTTCPWLFKLGCIFYHLIPGFFFDLLLRIQGK 385
            :|:.      ..|.|      |:.:....|..:.|:...|:.......|..|.|.:|:.||:.|:
Mouse   315 WGEV------EYHVISTFKRNPLEQAFRRPNVNLTSNHLLYHYWIAVSHKAPAFLYDIYLRMTGR 373

  Fly   386 KPILMRSYQKIHEVLLLLFPFNGKTYEMDMNNTNQLWDSMSPEDRSIFPFDMATLNWEEYFTRIL 450
            .|.:|::..::|:.::.|..|...::..:.:|.|.|.:.::|||:..|..|:..|:|.||.....
Mouse   374 SPRMMKTITRLHKAMVFLEYFTSNSWVWNTDNVNMLMNQLNPEDKKTFNIDVRQLHWAEYIENYC 438

  Fly   451 SGMRVFLYKESWDTLEQAKKRLFRFYILHRSLQLVLCLALGKIVWILYSVIANN 504
            .|.:.::..|....|..|:|.|.:...:......:|.:.:.:| :|..|.:|.|
Mouse   439 MGTKKYVLNEEMSGLPAARKHLNKLRNIRYGFNTILVILIWRI-FIARSQMARN 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sgp	NP_609241.1	FAR-N_SDR_e	12..333	CDD:187547	122/323 (38%)
		Sterile	368..459	CDD:460779	25/90 (28%)
Far1	NP_081655.2	FAR-N_SDR_e	11..330	CDD:187547	124/338 (37%)
		Sterile	357..447	CDD:460779	25/89 (28%)
		Necessary and sufficient for PEX19-mediated localization into peroxisome membrane. /evidence=ECO:0000250|UniProtKB:Q8WVX9	451..507		10/42 (24%)