Protein Alignment Sgp and Far1

DIOPT Version :10

• Sequence 1: NP_609241.1
• Gene: Sgp / 34188
• FlyBaseID: FBgn0032055
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_001011933.1
• Gene: Far1 / 293173
• RGDID: 1306647
• Length: 515
• Species: Rattus norvegicus
• Alignment Length: 506
• Identity: 168/506 - (33%)
• Similarity: 273/506 - (53%)
• Gaps: 24/506 - (4%)

  Fly     5 ILQFYKDKSVFVTGGTGFLGKVIIEKLLRS-TDVRRVYLLVRPKKNETVEGRFQAWKDEPVFKIL 68
            |.::|:.|::.:||.|||||||::|||||| ..|..||:|||.|..:|.:.|.:......:|..|
  Rat     4 IPEYYEGKNILLTGATGFLGKVLLEKLLRSCPKVNSVYVLVRQKAGQTPQERVEEILSGKLFDRL 68

  Fly    69 LKAKPEALKLVTPISGDCSEPGLGLSDGDRRMVTADVQVIIHSAASIRFVEPLQRALNINTRATR 133
            ....|:..:.:..|:.:.::|.|.||:.|:.::.....||.|.||::||.|.|:.|:.:|..|||
  Rat    69 RDENPDFRQKIIAINSELTQPKLALSEEDKEIIIDSTNVIFHCAATVRFNENLRDAVQLNVIATR 133

  Fly   134 LMIQLAKEMKGLEAFVHISTAFSNCPSQHIEERFYPEHLTCPAAKVLEFNETLSPDLLDKMAPAL 198
            .:|.||::||.||.|:|:|||::.|..:||:|..||..:  ...|:::..|.:...|::.:.|.|
  Rat   134 QLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPV--DPKKLIDSLEWMDDGLVNDITPKL 196

  Fly   199 MGKFPNTYTYTKALAEQVIQMEGQDLPICVFRPAIILANFKEPMSGWIDNLHGVVALIYGNTYGI 263
            :|..||||.|||||||.|:|.||..|.:.:.||:|:.|::|||..|||||.:|...|......||
  Rat   197 IGDRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKGI 261

  Fly   264 LRLLYVNPKADAIIVPGDYCANVALASGWQVAKNSESRSSSQLAAKKPPPI--YTLATTKSNSIT 326
            ||.:..:..|.|.:||.|...|.:||:.|....|            :|..|  |...|..:|...
  Rat   262 LRTMRASNNALADLVPVDVVVNTSLAAAWYSGVN------------RPRNIMVYNCTTGSTNPFH 314

  Fly   327 FGKAVKLGIHHNH---TIPVTKTIWYPFAHFTTCPWLFKLGCIFYHLIPGFFFDLLLRIQGKKPI 388
            :|   ::|.:.||   |.|:.:...:|:..|.:...:........|.:|....||.||:.|:||.
  Rat   315 WG---EVGDYLNHSFKTNPLNQVFRHPYVKFYSNNLMLHYWKGVKHTVPALLLDLALRLTGQKPW 376

  Fly   389 LMRSYQKIHEVLLLLFPFNGKTYEMDMNNTNQLWDSMSPEDRSIFPFDMATLNWEEYFTRILSGM 453
            :|::..::|:.::.|..|...::..:.:|.|.|.:.::|||:..|..|:..|:|.||......|.
  Rat   377 MMKTITRLHKAMVFLEYFTSNSWVWNTDNVNMLMNQLNPEDKKTFNIDVRQLHWAEYIENYCMGT 441

  Fly   454 RVFLYKESWDTLEQAKKRLFRFYILHRSLQLVLCLALGKIVWILYSVIANN 504
            :.::..|....|..|:|.|.:...:......:|.:.:.:| :|..|.:|.|
  Rat   442 KKYVLNEEMSGLPAARKHLNKLRNIRYGFNTILVILIWRI-FIARSQMARN 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sgp	NP_609241.1	FAR-N_SDR_e	12..333	CDD:187547	122/323 (38%)
		Sterile	368..459	CDD:460779	26/90 (29%)
Far1	NP_001011933.1	FAR-N_SDR_e	11..330	CDD:187547	126/335 (38%)
		Sterile	371..447	CDD:460779	20/75 (27%)
		Necessary and sufficient for PEX19-mediated localization into peroxisome membrane. /evidence=ECO:0000250|UniProtKB:Q8WVX9	451..507		10/42 (24%)