DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sgp and far1

DIOPT Version :9

Sequence 1:	NP_001260257.1	Gene:	Sgp / 34188	FlyBaseID:	FBgn0032055	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	XP_017948360.1	Gene:	far1 / 100038270	XenbaseID:	XB-GENE-973776	Length:	518	Species:	Xenopus tropicalis

Alignment Length:	507	Identity:	175/507 - (34%)
Similarity:	274/507 - (54%)	Gaps:	23/507 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ILQFYKDKSVFVTGGTGFLGKVIIEKLLRS-TDVRRVYLLVRPKKNETVEGRFQAWKDEPVFKIL 68
            |.:||:.|:|.:||.|||:|||::|||||| .:|:.||:|||||.::....|........:|..|
Frog     4 IPEFYRGKNVLITGATGFMGKVLLEKLLRSCPNVKAVYVLVRPKASQKPRERVAEMMSCKLFDRL 68

  Fly    69 LKAKPEALKLVTPISGDCSEPGLGLSDGDRRMVTADVQVIIHSAASIRFVEPLQRALNINTRATR 133
            ...:||..:.|..||.:.::|.|.||..|:.|:...:.::.|.||::||.|.|:.|:.:|..|||
Frog    69 RDEQPECAQKVIAISSELTQPELDLSKEDQDMLIDCIDIVFHCAATVRFNESLRDAMQLNVIATR 133

  Fly   134 LMIQLAKEMKGLEAFVHISTAFSNCPSQHIEERFYPEHLTCPAAKVLEFNETLSPDLLDKMAPAL 198
            .::.||:::|.||.|:|:|||::||..:.|||..||..:  ...|::|..|.:...|::.:.|.|
Frog   134 QLLYLAQKIKKLEVFIHVSTAYANCNRKQIEEMVYPPPV--DPKKLIESLEWMDDGLVNDITPKL 196

  Fly   199 MGKFPNTYTYTKALAEQVIQMEGQDLPICVFRPAIILANFKEPMSGWIDNLHGVVALIYGNTYGI 263
            :|..||||||||||||.|:|.||..|.|.:.||:|:.|::|||..|||||.:|...|......||
Frog   197 IGDRPNTYTYTKALAEYVVQQEGSKLNIAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKGI 261

  Fly   264 LRLLYVNPKADAIIVPGDYCANVALASGWQVAKNSESRSSSQLAAKKPPPIYTLATTKSNSITFG 328
            ||.:..:..|.|.::|.|...|..||:.|....|..||..:.|       :|...|..:|...:|
Frog   262 LRTMRASNNAVADLIPVDVVVNTTLAAAWYSGVNRYSRPRNIL-------VYNCTTGGTNPFHWG 319

  Fly   329 KAVKLGIHHNHTI------PVTKTIWYPFAHFTTCPWLFKLGCIFYHLIPGFFFDLLLRIQGKKP 387
            :.      ..|.|      |:.:....|..:.|:...|:.......|..|.|.:|:.|||.|:.|
Frog   320 EV------EYHVISTFKRNPLEQAFRRPNVNLTSNHLLYHYWIAVSHKAPAFLYDVYLRITGRSP 378

  Fly   388 ILMRSYQKIHEVLLLLFPFNGKTYEMDMNNTNQLWDSMSPEDRSIFPFDMATLNWEEYFTRILSG 452
            .:|::..::|:.::||..|...::..:..|||.|...:||:|:..|.||:..|:|.||......|
Frog   379 RMMKTITRLHKAMMLLEYFTSNSWVWNNENTNMLMSQLSPDDKKAFNFDVRQLHWAEYMENYCMG 443

  Fly   453 MRVFLYKESWDTLEQAKKRLFRFYILHRSLQLVLCLALGKIVWILYSVIANN 504
            .:.::..|....|..|:|.|.:...:......:|.:.:.: |:|..|.:|.|
Frog   444 TKKYVLNEEMSGLPAARKHLNKLRNIRYGFNTILVVLIWR-VFIARSQMARN 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sgp	NP_001260257.1	PLN02996	1..449	CDD:215538	163/450 (36%)
		FAR-N_SDR_e	12..333	CDD:187547	126/321 (39%)
		FAR_C	367..457	CDD:176924	29/89 (33%)
far1	XP_017948360.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	83	1.000	Domainoid score	I8217
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920