Protein Alignment Uba4 and UBA4

DIOPT Version :9

• Sequence 1: NP_001260255.1
• Gene: Uba4 / 34187
• FlyBaseID: FBgn0032054
• Length: 453
• Species: Drosophila melanogaster
• Sequence 2: NP_011979.1
• Gene: UBA4 / 856511
• SGDID: S000001153
• Length: 440
• Species: Saccharomyces cerevisiae
• Alignment Length: 467
• Identity: 183/467 - (39%)
• Similarity: 266/467 - (56%)
• Gaps: 52/467 - (11%)

  Fly     5 EVDSERTMLKREIAELRAALNQKEQCLRELDSLFSFATRPEQEVVGNDLESPDVAVHTKLTNDDI 69
            :..||...|:.|.|:||..|.::|...|:.                            .|:.::.
Yeast     8 DTTSELEALRLENAQLREQLAKREDSSRDY----------------------------PLSLEEY 44

  Fly    70 ARYSRQLILPDF-GVQGQLKLKNSSVLIVGLGGLGCPAAQYLAAAGCGHLGLVDYDEVERSNFHR 133
            .||.||:|:.:. ||.||:||||:.||:||.|||||||..|||.||.|.:|:||.|.||.||.||
Yeast    45 QRYGRQMIVEETGGVAGQVKLKNTKVLVVGAGGLGCPALPYLAGAGVGQIGIVDNDVVETSNLHR 109

  Fly   134 QILHSEDRCGMSKAESARIALLELNPHCEIQCHSRMLYPHNAMHIIRGYDVVLDCTDNVPTRYLL 198
            |:||...|.||.|.||||..:.:||||..:..:...|...||..|.:||:.:|||||:..||||:
Yeast   110 QVLHDSSRVGMLKCESARQYITKLNPHINVVTYPVRLNSSNAFDIFKGYNYILDCTDSPLTRYLV 174

  Fly   199 SDACVMLSKPLVSGSALKMDGQLTVYNYAN-GPCYRCIFPVPPPPEAVTNCGDGGVLGAVTGTIG 262
            ||..|.|...:||.|.|..:||||:.|:.| ||||||.:|.||||.|||:|.:|||:|...|.:|
Yeast   175 SDVAVNLGITVVSASGLGTEGQLTILNFNNIGPCYRCFYPTPPPPNAVTSCQEGGVIGPCIGLVG 239

  Fly   263 AMQALEAIKVIVGM--GDVLAGRLLIFDG-GSGVFRNIRIRSKRPNCHMCSAQPLITE------L 318
            .|.|:|.:|:|:|:  .:..:..|:::.| .....|..::|.::..|..|.....||:      .
Yeast   240 TMMAVETLKLILGIYTNENFSPFLMLYSGFPQQSLRTFKMRGRQEKCLCCGKNRTITKEAIEKGE 304

  Fly   319 INYEMFCGMHATDKNNPMLLLSTDERLSVEDYQQKIQ----AQPHLLIDVRPTAEFEICQLPEAV 379
            ||||:|||....:...|      |||:||:.:|:..:    ...|:.:||||:..:||...||||
Yeast   305 INYELFCGARNYNVCEP------DERISVDAFQRIYKDDEFLAKHIFLDVRPSHHYEISHFPEAV 363

  Fly   380 NVPLVEILD-DSYLKRLGKQLE--DKELPIVLVCRRGNDSQIAVQHLRNRFPTHFVRDLIGGLHA 441
            |:|:..:.| :..||:|.::|.  :|:..||::||.|||||:|.:.|:::|....|||:.||...
Yeast   364 NIPIKNLRDMNGDLKKLQEKLPSVEKDSNIVILCRYGNDSQLATRLLKDKFGFSNVRDVRGGYFK 428

  Fly   442 WTNSVDPSFPIY 453
            :.:.:|.:.|.|
Yeast   429 YIDDIDQTIPKY 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba4	NP_001260255.1	PRK07878	56..453	CDD:181156	172/414 (42%)
		ThiF_MoeB_HesA_family	71..299	CDD:238386	114/232 (49%)
		RHOD_ThiF	336..453	CDD:238784	44/123 (36%)
UBA4	NP_011979.1	ThiF_MoeB_HesA_family	46..279	CDD:238386	114/232 (49%)
		RHOD_ThiF	316..440	CDD:238784	45/129 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346548
Domainoid	1	1.000	225	1.000	Domainoid score	I432
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6108
Inparanoid	1	1.050	315	1.000	Inparanoid score	I466
Isobase	1	0.950	-	0	Normalized mean entropy	S1023
OMA	1	1.010	-	-		QHG53534
OrthoFinder	1	1.000	-	-		FOG0003489
OrthoInspector	1	1.000	-	-		oto99843
orthoMCL	1	0.900	-	-		OOG6_100543
Panther	1	1.100	-	-	LDO	PTHR10953
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1579
SonicParanoid	1	1.000	-	-		X2381
TreeFam	1	0.960	-	-
	16	15.740