DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uba4 and UBA3

DIOPT Version :9

Sequence 1:	NP_001260255.1	Gene:	Uba4 / 34187	FlyBaseID:	FBgn0032054	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	NP_015391.1	Gene:	UBA3 / 856179	SGDID:	S000006270	Length:	299	Species:	Saccharomyces cerevisiae

Alignment Length:	171	Identity:	41/171 - (23%)
Similarity:	69/171 - (40%)	Gaps:	23/171 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 VLIVGLGGLGCPAAQYLAAAG-CGHLGLVDYDEVERSNFHRQILHSEDRCGMSKAESARIALLEL 157
            :|::|.|||||...:.|.... ...:.:||.|.:|.:|.:||.|..:...|..||:.|...:...
Yeast     5 ILVLGAGGLGCEILKNLTMLSFVKQVHIVDIDTIELTNLNRQFLFCDKDIGKPKAQVAAQYVNTR 69

  Fly   158 NPHCEIQCHSRML------YPHNAMHIIRGYDVVLDCTDNVPTRYLLSDACVMLSK--------P 208
            .|..|:..|.:.|      :..:...||.|.|.:      .|.|: :::..|.|:.        |
Yeast    70 FPQLEVVAHVQDLTTLPPSFYKDFQFIISGLDAI------EPRRF-INETLVKLTLESNYEICIP 127

  Fly   209 LVSGSALKMDGQLTVYNYANGPCYRC-IFPVPPPPEAVTNC 248
            .:.|....:.|.:.........|:.| |..:|...:.|..|
Yeast   128 FIDGGTEGLKGHVKTIIPGITACWECSIDTLPSQQDTVPMC 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uba4	NP_001260255.1	PRK07878	56..453	CDD:181156	41/171 (24%)
		ThiF_MoeB_HesA_family	71..299	CDD:238386	41/171 (24%)
		RHOD_ThiF	336..453	CDD:238784
UBA3	NP_015391.1	Uba3_RUB	4..294	CDD:238765	41/171 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810