DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uba4 and Uba2

DIOPT Version :9

Sequence 1:	NP_001260255.1	Gene:	Uba4 / 34187	FlyBaseID:	FBgn0032054	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	NP_524756.2	Gene:	Uba2 / 44496	FlyBaseID:	FBgn0029113	Length:	700	Species:	Drosophila melanogaster

Alignment Length:	147	Identity:	44/147 - (29%)
Similarity:	71/147 - (48%)	Gaps:	1/147 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 LKNSSVLIVGLGGLGCPAAQYLAAAGCGHLGLVDYDEVERSNFHRQILHSEDRCGMSKAESARIA 153
            :|.|.||:||.||:||...:.|..:|...:.::|.|.::.||.:||.|...:..|.|||..||.:
  Fly    17 VKKSKVLVVGAGGIGCEVLKNLVLSGFTDIEIIDLDTIDLSNLNRQFLFHREHVGKSKARVARES 81

  Fly   154 LLELNPHCEIQC-HSRMLYPHNAMHIIRGYDVVLDCTDNVPTRYLLSDACVMLSKPLVSGSALKM 217
            .|..||..:|.. |..:......::..:.:|:||...||...|..::..|:....||:.......
  Fly    82 ALSFNPDAKITAYHDSVTSTDYGVNFFKKFDLVLSALDNRAARNHVNRMCLNADVPLIESGTAGY 146

  Fly   218 DGQLTVYNYANGPCYRC 234
            :||:.:.......||.|
  Fly   147 NGQVELIKRGLTQCYEC 163

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uba4	NP_001260255.1	PRK07878	56..453	CDD:181156	44/147 (30%)
		ThiF_MoeB_HesA_family	71..299	CDD:238386	44/147 (30%)
		RHOD_ThiF	336..453	CDD:238784
Uba2	NP_524756.2	ThiF	7..>177	CDD:279270	44/147 (30%)
		Uba2_SUMO	21..459	CDD:238766	42/143 (29%)
		UAE_UbL	467..552	CDD:291402
		UBA2_C	573..691	CDD:292812
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446849
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10953
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840