DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uba4 and Atg7

DIOPT Version :9

Sequence 1:	NP_001260255.1	Gene:	Uba4 / 34187	FlyBaseID:	FBgn0032054	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	NP_611350.1	Gene:	Atg7 / 37141	FlyBaseID:	FBgn0034366	Length:	684	Species:	Drosophila melanogaster

Alignment Length:	221	Identity:	54/221 - (24%)
Similarity:	87/221 - (39%)	Gaps:	56/221 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 ILPDFGVQGQLKLKNSSVLIVGLGGLGCPAAQYLAAAGCGHLGLVDYDEVERSNFHRQIL--HSE 139
            ::||..::   .:..:..|:.|.|.|||..|:.|.:.|..|:.|:|..:|..||..||.|  |::
  Fly   328 LVPDLNLE---IISQTKCLLFGAGTLGCAVARNLLSWGFKHITLLDSGKVGFSNPVRQNLYTHAD 389

  Fly   140 DRCG-MSKAESARIALLELNPHCEIQCH-----------SRMLYPHNAMH------IIRGYDVVL 186
            ...| ..||.:|...|.|:||..|...:           ...|......|      :::.:||:.
  Fly   390 AVAGNRMKATTAAQRLKEINPSAETAGYVLEIPMPGHTIGESLLAQTKEHLKVIEKLVQDHDVIF 454

  Fly   187 DCTDNVPTRYL--LSDACVMLSKPLVSGSALKMDGQLTVYNYANGPCYRCIFPVPPPPEAVTNCG 249
            ..||:..:|:|  |..|.   .:.:|..:||..|..|.:   .:|...:             ..|
  Fly   455 LLTDSRESRWLPTLLGAA---KEKIVINAALGFDSYLVM---RHGTTRK-------------EAG 500

  Fly   250 DGGVLGAVTGTIGAMQALEAIKVIVG 275
            |.|            |.:|.:|.|.|
  Fly   501 DDG------------QEIEGLKCING 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uba4	NP_001260255.1	PRK07878	56..453	CDD:181156	54/221 (24%)
		ThiF_MoeB_HesA_family	71..299	CDD:238386	54/221 (24%)
		RHOD_ThiF	336..453	CDD:238784
Atg7	NP_611350.1	ATG7_N	9..303	CDD:293029
		E1_like_apg7	11..682	CDD:273590	54/221 (24%)
		Apg7	341..658	CDD:238763	52/205 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446853
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10953
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840