DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uba4 and uba7

DIOPT Version :9

Sequence 1:	NP_001260255.1	Gene:	Uba4 / 34187	FlyBaseID:	FBgn0032054	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	XP_005155933.1	Gene:	uba7 / 100001302	ZFINID:	ZDB-GENE-121120-4	Length:	1016	Species:	Danio rerio

Alignment Length:	194	Identity:	60/194 - (30%)
Similarity:	83/194 - (42%)	Gaps:	30/194 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 PEQE--VVGNDLESPDVAVHTKLTNDDIARYSRQLILPDFGVQGQLKLKNSSVLIVGLGGLGCPA 106
            |::|  |:..|..:|         .|  :||..|:.:  ||...|.|||.....:||.|.:||..
Zfish   390 PQEEGGVLSEDACAP---------RD--SRYDGQIAV--FGSDFQNKLKKQKYFLVGAGAIGCEL 441

  Fly   107 AQYLAAAGC-----GHLGLVDYDEVERSNFHRQILHSEDRCGMSKAESARIALLELNPHCEI--- 163
            .:..|..|.     |.:.:.|.|.:||||.:||.|......|..|:|:|..|:.|:||...|
Zfish   442 LKNFALIGLGAGEGGSITVTDMDSIERSNLNRQFLFRSQDIGRPKSEAAAEAVKEMNPFMNIIAQ 506

  Fly   164 ---QC-HSRMLYPHNAMHIIRGYDVVLDCTDNVPTRYLLSDACVMLSKPLVSGSALKMDGQLTV 223
               .| .:..:|.|:   ...|.|.|....|||..|..|...||...||::.|..|...|...|
Zfish   507 QNRVCAETEEVYTHS---FYTGLDGVAAALDNVDARVYLDQCCVRNKKPMLEGGTLGSKGHTMV 567

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uba4	NP_001260255.1	PRK07878	56..453	CDD:181156	56/180 (31%)
		ThiF_MoeB_HesA_family	71..299	CDD:238386	54/165 (33%)
		RHOD_ThiF	336..453	CDD:238784
uba7	XP_005155933.1	Ube1	5..1013	CDD:273603	60/194 (31%)
		Ube1_repeat1	10..393	CDD:238768	1/2 (50%)
		E1_4HB	258..326	CDD:292809
		E1_enzyme_family	428..970	CDD:304554	45/143 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910