Protein Alignment Bace and BAR1

DIOPT Version :9

• Sequence 1: NP_001285756.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_012249.1
• Gene: BAR1 / 854797
• SGDID: S000001277
• Length: 587
• Species: Saccharomyces cerevisiae
• Alignment Length: 382
• Identity: 103/382 - (26%)
• Similarity: 159/382 - (41%)
• Gaps: 98/382 - (25%)

  Fly    61 LSNSMNMAYYGAISIGTPAQSFKVLFDSGSSNLWV----------------------------PS 97
            |.:...|.|...:.||||:||..||||:||::.||                            ||
Yeast    37 LQHEEEMYYATTLDIGTPSQSLTVLFDTGSADFWVMDSSNPFCLPNSNTSSYSNATYNGEEVKPS 101

  Fly    98 NTCKSDACLTHNQYDSSASSTYVANGESFSIQYGTGSLT-GYLSTDTVDVNGLSIQSQTFAESTN 161
            ..|:|.:  |:|::.|| :..|:.||. |.|.|..|:.. |...|:||.:||:.|
Yeast   102 IDCRSMS--TYNEHRSS-TYQYLENGR-FYITYADGTFADGSWGTETVSINGIDI---------- 152

  Fly   162 EPGTNFNDANF-----DGILGMAY---ESL-AVDGVAPPFYN-----MVSQGLVDNSVFSFYLAR 212
             |...|..|.:     .|:||:.:   ||: ..:|....:|.     :.|:.::|...:|.:|..
Yeast   153 -PNIQFGVAKYATTPVSGVLGIGFPRRESVKGYEGAPNEYYPNFPQILKSEKIIDVVAYSLFLNS 216

  Fly   213 DGTSTMGGELIFGGSDASLYSGALTYVP--------ISEQGYWQFTMAGSSIDGYSLCD------ 263
            ..:.|  |.::||..|.|.:||.|...|        :........|:.|......|.|:
Yeast   217 PDSGT--GSIVFGAIDESKFSGDLFTFPMVNEYPTIVDAPATLAMTIQGLGAQNKSSCEHETFTT 279

  Fly   264 -DCQAIADTGTSLIVAPYNAYITLSEILNVG---EDG--YLDCSSVSSLPDVTFN--IGGTNFVL 320
             ....:.|:||||:.||......::..:|..   |:|  .|||.  .|:.||.:|  .|.....:
Yeast   280 TKYPVLLDSGTSLLNAPKVIADKMASFVNASYSEEEGIYILDCP--VSVGDVEYNFDFGDLQISV 342

  Fly   321 KPSAYII--QSDGNCMSAFEYMG------TDFWILGDVFIGQYYTEFDLGNNRIGFA 369
            ..|:.|:  :::|:      |.|      .|..:|||||:...|..|||.|.:|..|
Yeast   343 PLSSLILSPETEGS------YCGFAVQPTNDSMVLGDVFLSSAYVVFDLDNYKISLA 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bace	NP_001285756.1	pepsin_retropepsin_like	59..369	CDD:299705	102/380 (27%)
		Asp	68..371	CDD:278455	101/375 (27%)
BAR1	NP_012249.1	SAP_like	43..395	CDD:133141	102/376 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.770