Protein Alignment Bace and YPS3

DIOPT Version :9

• Sequence 1: NP_001285756.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_013222.1
• Gene: YPS3 / 850812
• SGDID: S000004111
• Length: 508
• Species: Saccharomyces cerevisiae
• Alignment Length: 415
• Identity: 117/415 - (28%)
• Similarity: 173/415 - (41%)
• Gaps: 75/415 - (18%)

  Fly     5 IAVVVLLAALASAELHRV---------PILKEQNFVKTRQNVLAEKSYLRTKYQLPSLRSVDEEQ 60
            :|.|..||.|.|....||         |..|::|         .:...|       |.||...|:
Yeast     5 LAAVATLAVLTSPAFGRVLPDGKYVKIPFTKKKN---------GDNGEL-------SKRSNGHEK 53

  Fly    61 LSNSMNMAYYGA-ISIGTPAQSFKVLFDSGSSNLWVPSN---TCKSDA-CLTHNQYDSSASSTYV 120
            ...:...::|.. ::||||:|:..||.|:||::||||..   .|.|.. |..:..:|.:.|||:.
Yeast    54 FVLANEQSFYSVELAIGTPSQNLTVLLDTGSADLWVPGKGNPYCGSVMDCDQYGVFDKTKSSTFK 118

  Fly   121 ANGES-FSIQYGTGSLT-GYLSTDTVDVNGLSIQSQTFAESTNEPGTNFNDANFDGILGMAYESL 183
            ||..| |...||.|:.. |....|.:..|.|.:...:||.: ||..:.|      |:||:...:|
Yeast   119 ANKSSPFYAAYGDGTYAEGAFGQDKLKYNELDLSGLSFAVA-NESNSTF------GVLGIGLSTL 176

  Fly   184 AV---------DGVAPPFYN----MVSQGLVDNSVFSFYLARDGTSTMGGELIFGGSDASLYSGA 235
            .|         |..:..:.|    :...|.:|.:.:|.:|..:..|:  |.::||..|.|.|.|.
Yeast   177 EVTYSGKVAIMDKRSYEYDNFPLFLKHSGAIDATAYSLFLNDESQSS--GSILFGAVDHSKYEGQ 239

  Fly   236 LTYVPI----SEQGYWQFTMAGSSIDGYSLCDD----------CQAIADTGTSLIVAPYNAYITL 286
            |..:|:    ..|||........::.|..|..|          ..|:.|:||:|...|..|...|
Yeast   240 LYTIPLVNLYKSQGYQHPVAFDVTLQGLGLQTDKRNITLTTTKLPALLDSGTTLTYLPSQAVALL 304

  Fly   287 SEILNVGED---GYLD--CSSVSSLPDVTFNIGGTNFVLKPSAYIIQ-SDGNCMSA-FEYMGTDF 344
            ::.||....   ||.:  |.|..:...|.|:.||.......|.:.:| |.|.|:.| ....|...
Yeast   305 AKSLNASYSKTLGYYEYTCPSSDNKTSVAFDFGGFRINAPLSDFTMQTSVGTCVLAIIPQAGNAT 369

  Fly   345 WILGDVFIGQYYTEFDLGNNRIGFA 369
            .||||.|:...|..:||.|..|..|
Yeast   370 AILGDSFLRNAYVVYDLDNYEISLA 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bace	NP_001285756.1	pepsin_retropepsin_like	59..369	CDD:299705	101/350 (29%)
		Asp	68..371	CDD:278455	101/343 (29%)
YPS3	NP_013222.1	SAP_like	61..396	CDD:133141	101/343 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.770