Protein Alignment Bace and asp-19

DIOPT Version :9

• Sequence 1: NP_001285756.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001123079.1
• Gene: asp-19 / 6418790
• WormBaseID: WBGene00077655
• Length: 223
• Species: Caenorhabditis elegans
• Alignment Length: 186
• Identity: 64/186 - (34%)
• Similarity: 102/186 - (54%)
• Gaps: 11/186 - (5%)

  Fly    71 GAISIGTPAQSFKVLFDSGSSNLWVPSNTCKSDAC-----LTHNQYDSSASSTYVANGESFSIQY 130
            |.|:||||.||..|..|:.|:|.||..:.|.|..|     :..::::::.|:::|....:||.:|
 Worm    41 GNITIGTPPQSASVFMDTTSANWWVIGSKCTSANCNGYSGIRKHKFNTTKSTSFVEGNRTFSTEY 105

  Fly   131 GTGSLTGYLSTDTVDVNGLSIQSQTFAESTNEPGTNFNDANFDGILGMAYESLAVDGVAPPFYNM 195
            |.  .||||.||||.:.||:|..|....:| ..|..|....:.||..:|:.:|:||.|.||...:
 Worm   106 GL--CTGYLGTDTVQMGGLTITKQELGIAT-IVGLGFGLKPYVGIFELAWPALSVDQVTPPMQKL 167

  Fly   196 VSQGLVDNSVFSFYL-ARDGTSTMG--GELIFGGSDASLYSGALTYVPISEQGYWQ 248
            :||..:|..:|:.:| .:|....:|  |.:.:||.|.......:|||.:|.:.:||
 Worm   168 ISQNQLDAPMFTIWLDQKDQGVYVGYTGLITYGGFDNKNCDANVTYVALSSKTFWQ 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bace	NP_001285756.1	pepsin_retropepsin_like	59..369	CDD:299705	64/186 (34%)
		Asp	68..371	CDD:278455	64/186 (34%)
asp-19	NP_001123079.1	pepsin_like	40..>223	CDD:133138	62/184 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161975
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840