Protein Alignment Bace and mgc108380

DIOPT Version :9

• Sequence 1: NP_001285756.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001027480.1
• Gene: mgc108380 / 613072
• -ID: -
• Length: 384
• Species: Xenopus tropicalis
• Alignment Length: 395
• Identity: 164/395 - (41%)
• Similarity: 227/395 - (57%)
• Gaps: 44/395 - (11%)

  Fly     7 VVVLLAALASAELHRVP---------------ILKEQNFVKTRQNVLAEKSYLRTKYQLPSLRSV 56
            |:..:....|..|.|||               ||||  |:||.:...|.|.:...||..    :|
 Frog     5 VLAFICLQLSEGLVRVPLKRYKSARDIMRERGILKE--FMKTHKRDPALKYHFNEKYDF----AV 63

  Fly    57 DEEQLSNSMNMAYYGAISIGTPAQSFKVLFDSGSSNLWVPSNTCKSDACLTHNQYDSSASSTYVA 121
            ..|.:  .|:..|||.||||||.|:|.||||:|||||||||.:|:|:||..||.::.|.||||.:
 Frog    64 AYEPM--YMDTYYYGEISIGTPPQNFLVLFDTGSSNLWVPSTSCQSEACSNHNLFNPSQSSTYTS 126

  Fly   122 NGESFSIQYGTGSLTGYLSTDTVDVNGLSIQSQTFAESTNEPGTNFNDANFDGILGMAYESLAVD 186
            ||:.||:.||:||:||....|||.|.|||:.:|.|..:..|.|::|..:.||||.||||.:::..
 Frog   127 NGQQFSMSYGSGSVTGVFGYDTVTVQGLSLNNQEFGLTYTESGSSFYYSKFDGIFGMAYPAMSAG 191

  Fly   187 GVAPPFYNMVSQGLVDNSVFSFYLARDGTSTMGGELIFGGSDASLYSGALTYVPISEQGYWQFTM 251
            |.......|:.|.|:...:||.|:     |:..||:||||.|.:||||.:.:.|::::.|||..:
 Frog   192 GATTAMQGMLQQNLLTYPIFSVYM-----SSQSGEVIFGGVDNNLYSGQIQWSPVTQEVYWQIGI 251

  Fly   252 AGSSIDGYSL--CDD-CQAIADTGTSLIVAPYNAYITLSEILNVGEDGY-----LDCSSVSSLPD 308
            ....|:|.:.  |.. ||||.|||||.:..|.....||  :.|:|...|     ::|:||.:||.
 Frog   252 DEFLINGQATGWCSQGCQAIVDTGTSPLTIPQQYMGTL--LQNLGAQNYNGMFVVNCNSVQNLPT 314

  Fly   309 VTFNIGGTNFVLKPSAYIIQSDGNCMSAFE--YM----GTDFWILGDVFIGQYYTEFDLGNNRIG 367
            :||.|.|..|.:.||.||:|::|.|....|  |:    |...|||||||:.|||:.:|:.|||:|
 Frog   315 ITFVINGVQFPIPPSGYIVQTNGYCTVGVEETYLPSQNGQPLWILGDVFLRQYYSVYDMSNNRVG 379

  Fly   368 FAPVA 372
            ||..|
 Frog   380 FAQAA 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bace	NP_001285756.1	pepsin_retropepsin_like	59..369	CDD:299705	143/323 (44%)
		Asp	68..371	CDD:278455	143/316 (45%)
mgc108380	NP_001027480.1	A1_Propeptide	17..45	CDD:369623	10/29 (34%)
		pepsin_retropepsin_like	71..383	CDD:386101	143/318 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1428
SonicParanoid	1	1.000	-	-		X1456
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.960