Protein Alignment Bace and pgc

DIOPT Version :9

• Sequence 1: NP_001285756.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001015682.1
• Gene: pgc / 548353
• XenbaseID: XB-GENE-5838607
• Length: 385
• Species: Xenopus tropicalis
• Alignment Length: 381
• Identity: 158/381 - (41%)
• Similarity: 226/381 - (59%)
• Gaps: 33/381 - (8%)

  Fly    16 SAELHRVPILKEQNFVKTRQNVLAE---KSYLRTKYQLPSLRSVDEEQLSN--------SMNMAY 69
            |..|.|||:   :.|..||:.:...   ..:|:|..:.|:::.....| ||        .:::.|
 Frog    14 SEGLVRVPL---KRFKSTRETMKENGVLNDFLKTHKREPAIKYNWNSQ-SNFGVAYEPMYLDIYY 74

  Fly    70 YGAISIGTPAQSFKVLFDSGSSNLWVPSNTCKSDACLTHNQYDSSASSTYVANGESFSIQYGTGS 134
            :|.||||||.|:|.|.||:|||||||.|..|:|.||..|..::.|.||||.:|.:.||:.||:||
 Frog    75 FGEISIGTPPQNFLVAFDTGSSNLWVASTYCQSQACTNHPLFNPSLSSTYTSNNQQFSMWYGSGS 139

  Fly   135 LTGYLSTDTVDVNGLSIQSQTFAESTNEPGTNFNDANFDGILGMAYESLAVDGVAPPFYNMVSQG 199
            :||.|..|||.|.|||||:|....|..||.:.|..:.||||.||||:||:..|.:.....::.|.
 Frog   140 MTGVLGYDTVTVQGLSIQNQELGLSVTEPSSFFYYSKFDGIFGMAYQSLSAGGASTAVQGLIQQN 204

  Fly   200 LVDNSVFSFYLARDGTSTMGGELIFGGSDASLYSGALTYVPISEQGYWQFTMAGSSIDGYSL--C 262
            |:...||||||     ::..||:||||.|.||:||.:.:.|::::.|||..:...|::|.:.  |
 Frog   205 LIPQPVFSFYL-----TSQSGEVIFGGVDNSLFSGQIYWTPVTQEIYWQIAIDEFSVNGQATGWC 264

  Fly   263 DD-CQAIADTGTSLIVAPYNAYITLSEILNVGE--DG--YLDCSSVSSLPDVTFNIGGTNFVLKP 322
            .. ||.|.||||.|:..|.....||.:.:...|  :|  .::|:||.:||.::|.|.|..|.:.|
 Frog   265 SQGCQGIVDTGTPLLTIPQQYLSTLVQYVGAQEAQNGQFLVNCNSVQNLPPISFTISGIQFSIPP 329

  Fly   323 SAYIIQSDGNCMSAFE--YM----GTDFWILGDVFIGQYYTEFDLGNNRIGFAPVA 372
            ||||:|.:|.|:..||  |:    |...|||||||:.|||:.:|.|||::|||.:|
 Frog   330 SAYILQMNGYCVVGFESTYLPSRNGQPLWILGDVFLRQYYSVYDFGNNQVGFASMA 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bace	NP_001285756.1	pepsin_retropepsin_like	59..369	CDD:299705	144/330 (44%)
		Asp	68..371	CDD:278455	143/315 (45%)
pgc	NP_001015682.1	A1_Propeptide	17..45	CDD:369623	8/30 (27%)
		pepsin_retropepsin_like	71..383	CDD:386101	142/316 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930