Protein Alignment Bace and CG5863

DIOPT Version :9

• Sequence 1: NP_001285756.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_650623.1
• Gene: CG5863 / 42096
• FlyBaseID: FBgn0038507
• Length: 395
• Species: Drosophila melanogaster
• Alignment Length: 389
• Identity: 178/389 - (45%)
• Similarity: 250/389 - (64%)
• Gaps: 17/389 - (4%)

  Fly     1 MFKTIAVVVLLAALASAELHRVPILKEQNFVKTRQNVLAEKSYLRTKYQLPSLRSVDE------E 59
            ::.::.::.|..|....:|.|:|:..:.:|:.:|:...|.:|.|..||.:...:.|..      |
  Fly     7 LWLSLWILCLFWAKCQGQLIRIPMQFQASFMASRRQHRAGRSSLLAKYNVVGGQEVTSRNGGATE 71

  Fly    60 QLSNSMNMAYYGAISIGTPAQSFKVLFDSGSSNLWVPSNTC--KSDACLTHNQYDSSASSTYVAN 122
            .|.|.:|:.|.|.||||:|.|.|.:|||:||:||||||..|  ||.||..|::|::|||||:|.:
  Fly    72 TLDNRLNLEYAGPISIGSPGQPFNMLFDTGSANLWVPSAECSPKSVACHHHHRYNASASSTFVPD 136

  Fly   123 GESFSIQYGTGSLTGYLSTDTVDVNGLSIQSQTFAESTNEPGTNFNDANFDGILGMAYESLAVDG 187
            |..|||.||||||:|.|:.|||.:..|.:|:|||..:|:|||..|.|.||.||:|:.:..:|..|
  Fly   137 GRRFSIAYGTGSLSGRLAQDTVAIGQLVVQNQTFGMATHEPGPTFVDTNFAGIVGLGFRPIAELG 201

  Fly   188 VAPPFYNMVSQGLVDNSVFSFYLARDGTSTMGGELIFGGSDASLYSGALTYVPISEQGYWQFTMA 252
            :.|.|.:|..|.|||..||||||.|:|:...||||:|||.|.:.:||:|||||::..|||||.:.
  Fly   202 IKPLFESMCDQQLVDECVFSFYLKRNGSERKGGELLFGGVDKTKFSGSLTYVPLTHAGYWQFPLD 266

  Fly   253 GSSIDGYSLCDDCQAIADTGTSLIVAPYNAYITLSEILN---VGEDGY-LDCSSVSSLPDVTFNI 313
            ...:.|..:..:.||||||||||:.||...|:.::.:|.   ...:.| |:||.:.|||::.|.|
  Fly   267 VIEVAGTRINQNRQAIADTGTSLLAAPPREYLIINSLLGGLPTSNNEYLLNCSEIDSLPEIVFII 331

  Fly   314 GGTNFVLKPSAYIIQS---DGN--CMSAFEYMGTDFWILGDVFIGQYYTEFDLGNNRIGFAPVA 372
            ||..|.|:|..|::.:   ||:  |:|||..|..:||||||||||:|||.||.|..||||||.|
  Fly   332 GGQRFGLQPRDYVMSATNDDGSSICLSAFTLMDAEFWILGDVFIGRYYTAFDAGQRRIGFAPAA 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bace	NP_001285756.1	pepsin_retropepsin_like	59..369	CDD:299705	161/320 (50%)
		Asp	68..371	CDD:278455	159/313 (51%)
CG5863	NP_650623.1	pepsin_retropepsin_like	71..392	CDD:299705	161/320 (50%)
		Asp	80..394	CDD:278455	159/313 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455529
Domainoid	1	1.000	97	1.000	Domainoid score	I1884
eggNOG	1	0.900	-	-		E1_KOG1339
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	307	1.000	Inparanoid score	I2599
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	1	1.000	-	-		mtm978
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1456
	10	9.900