Protein Alignment Bace and CG5860

DIOPT Version :10

• Sequence 1: NP_609235.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_650622.1
• Gene: CG5860 / 42095
• FlyBaseID: FBgn0038506
• Length: 370
• Species: Drosophila melanogaster
• Alignment Length: 380
• Identity: 130/380 - (34%)
• Similarity: 201/380 - (52%)
• Gaps: 24/380 - (6%)

  Fly     1 MFKTIAVVVLLAAL--ASAELHRVPILKEQNFVKTRQNVLAEKSYLRTKYQLPSLRSVDEEQLSN 63
            |.:.:..::...:|  |:.::.:||:...::|.::...:....:......||..|       |..
  Fly     1 MLRVLCFLLAFLSLVFATQKILKVPLYVRRSFNESEVFLARSATEGGETLQLQLL-------LQT 58

  Fly    64 SMNMAYYGAISIGTPAQSFKVLFDSGSSNLWVPSNTC--KSDACLTHNQYDSSASSTYVANGESF 126
            ..||.|||.|::|.|.|:|.|:||:||||.|:||..|  .:.||..|.:|:||.||:|:.:|.:|
  Fly    59 HNNMEYYGTIAMGNPRQNFTVIFDTGSSNTWLPSVNCPMSNSACQNHRKYNSSRSSSYIPDGRNF 123

  Fly   127 SIQYGTGSLTGYLSTDTVDVNGLSIQSQTFAESTNEPGTNFNDANFDGILGMAYESLAVDGVAPP 191
            :::||:|.:.||||.||:.:.|..:...||.||.......|:...|||::|:....|:.....|.
  Fly   124 TLRYGSGMVVGYLSKDTMHIAGAELPHFTFGESLFLQHFAFSSVKFDGLVGLGLGVLSWSNTTPF 188

  Fly   192 FYNMVSQGLVDNSVFSFYLARDGTSTMGGELIFGGSDASLYSGALTYVPISEQGYWQFTMAGSSI 256
            ...:.:|.|::..|||.||.||..     |::|||.|.|.:.|.|.|||:|:...|...::.||:
  Fly   189 LELLCAQRLLEKCVFSVYLRRDPR-----EIVFGGFDESKFEGKLHYVPVSQWHTWSLQISKSSV 248

  Fly   257 DGYSLCDDCQAIADTGTSLIVAPYNAYITLSEILNVG-EDGY--LDCSSVSSLPDVTFNIGGTNF 318
            ....:.....||.||||||::.|...|..|...|:.. ::||  :.|.| .|||::...||...|
  Fly   249 GTKQIGGKSNAILDTGTSLVLVPQQTYHNLLNTLSAKLQNGYFVVACKS-GSLPNINILIGDKVF 312

  Fly   319 VLKPSAYIIQ----SDGNCMSAFEYMGTDFWILGDVFIGQYYTEFDLGNNRIGFA 369
            .|..|.||::    ....|:.|...:...||:|||:|:.:|||.||....|||.|
  Fly   313 PLTSSDYIMEVLLDRKPACVLAIAPINRGFWVLGDIFLRRYYTVFDATEKRIGLA 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bace	NP_609235.1	pepsin_retropepsin_like	59..369	CDD:472175	120/318 (38%)
CG5860	NP_650622.1	Asp	63..369	CDD:394983	118/311 (38%)