Protein Alignment Bace and asp-2

DIOPT Version :9

• Sequence 1: NP_001285756.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_872129.1
• Gene: asp-2 / 34700645
• WormBaseID: WBGene00000215
• Length: 429
• Species: Caenorhabditis elegans
• Alignment Length: 436
• Identity: 145/436 - (33%)
• Similarity: 216/436 - (49%)
• Gaps: 83/436 - (19%)

  Fly     3 KTIAVVVLLAALASAELHRVPILKEQNFVKTRQNVLAEKSYLRTKYQLPSLRSVDEEQLSNSMNM 67
            :.:.:::.|.|.|.|.:.:||::|.:.:   |..::.|..:::.:......|.:..:| ||.|::
 Worm     2 QNLFLLLALVAAALAAVVQVPLVKIEPY---RNRLIREGRWVQYRKDREIRRFMMNKQ-SNDMSV 62

  Fly    68 ----------AYYGAISIGTPAQSFKVLFDSGSSNLWVPSNTC---------------------- 100
                      ||.|.|:||||.|.|||:.|:||||||:|..||
 Worm    63 GQYVNDYEDEAYVGNITIGTPQQQFKVILDTGSSNLWIPDITCGTKPENCSTVPACRGIICQFEC 127

  Fly   101 -----------KSDACLTHNQYDSSASSTYVANGESFSIQYGTGSLTGYLSTDTVDVNG-----L 149
                       .:|:|...|::|:|.||:|..||.:|.|:|||||..|:|..||:...|     |
 Worm   128 DDQACCGAGANYTDSCFYQNKFDASKSSSYKTNGRNFIIEYGTGSARGFLGQDTITFGGIGEPQL 192

  Fly   150 SIQSQTFAESTNEPGTNFNDANFDGILGMAYESLAVDGVAPPFYNMVSQGLVDNSVFSFYLARDG 214
            ::.:..|.::|: ....|.....|||||:|::|:|||.:.|||.|.::|.|||..:|:.:|..:|
 Worm   193 AVPNTVFGQATS-LAAFFEGQPLDGILGLAFKSIAVDQITPPFINAINQNLVDLPLFTVFLEHEG 256

  Fly   215 --TSTMGGELIFGGSDASLYSGALTYVPISEQGYWQFTMAGSSIDGYSLCDDCQAIADTGTSLIV 277
              ....||...:||.|.......:.|.|:|...|:||.|:......|......|.|:|||||||.
 Worm   257 DQNGVQGGVYTYGGIDTKNCGPVIAYQPLSSATYYQFKMSAIGSGSYHSSKGWQVISDTGTSLIG 321

  Fly   278 APYNAYITLSEILN-VG---EDGY----LDCSSVSSLPDVT-----FNIGGTNFVLKPSAYIIQS 329
            .| .||:  |.|.: ||   .|.|    |.||:..:..|:|     :||..:|.:      |...
 Worm   322 GP-KAYV--SAIADAVGATWRDDYGVYILPCSAKINTLDITIGNQVYNIDSSNTI------IPLG 377

  Fly   330 DG--NCMSA-FEYMGTDF---WILGDVFIGQYYTEFDLGNNRIGFA 369
            ||  ||:.| |.:....|   |||||.||.||...:|:|..|:|||
 Worm   378 DGSNNCIYAIFPFSSGGFGPSWILGDPFIRQYCNIYDVGTQRVGFA 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bace	NP_001285756.1	pepsin_retropepsin_like	59..369	CDD:299705	133/378 (35%)
		Asp	68..371	CDD:278455	131/361 (36%)
asp-2	NP_872129.1	Asp	73..424	CDD:365818	131/361 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.030