Protein Alignment Bace and CG17134

DIOPT Version :9

• Sequence 1: NP_001285756.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_609458.1
• Gene: CG17134 / 34494
• FlyBaseID: FBgn0032304
• Length: 391
• Species: Drosophila melanogaster
• Alignment Length: 389
• Identity: 214/389 - (55%)
• Similarity: 267/389 - (68%)
• Gaps: 20/389 - (5%)

  Fly     3 KTIAVVVLLAAL--ASAELHRVPILKEQNFVKTRQNVLAEKSYLRTKYQLPSLRSVD------EE 59
            :.:.|:::|..:  ::|:|:||.:...:||.||..:|.|||:.|.:||...:..|..      .|
  Fly     2 RQLLVLLVLVGIGHSAAKLNRVQLQVNKNFTKTHGSVKAEKTVLASKYSFLAETSFSVSSSGATE 66

  Fly    60 QLSNSMNMAYYGAISIGTPAQSFKVLFDSGSSNLWVPSNTC--KSDACLTHNQYDSSASSTYVAN 122
            .|.||||..|||.|:||||.|.|.:|||:||:||||||.:|  .:.||..||:||||||||||||
  Fly    67 NLHNSMNNEYYGVIAIGTPEQRFNILFDTGSANLWVPSASCPASNTACQRHNKYDSSASSTYVAN 131

  Fly   123 GESFSIQYGTGSLTGYLSTDTVDVNGLSIQSQTFAESTNEPGTNFNDANFDGILGMAYESLAVDG 187
            ||.|:|:||||||:|:||.|.|.:.|:|||:|||.|:.:||||.|.||.|.||||:|:.::||||
  Fly   132 GEEFAIEYGTGSLSGFLSNDIVTIAGISIQNQTFGEALSEPGTTFVDAPFAGILGLAFSAIAVDG 196

  Fly   188 VAPPFYNMVSQGLVDNSVFSFYLARDGTSTMGGELIFGGSDASLYSGALTYVPISEQGYWQFTMA 252
            |.|||.||:||||:|..|.||||.|.||:..|||||.||.|:|||.|:|||||:|...||||.:.
  Fly   197 VTPPFDNMISQGLLDEPVISFYLKRQGTAVRGGELILGGIDSSLYRGSLTYVPVSVPAYWQFKVN 261

  Fly   253 GSSIDGYSLCDDCQAIADTGTSLIVAPYNAYITLSEIL----NVGEDGYLDCSSVSSLPDVTFNI 313
            ....:|..||:.||||||||||||..|..||..::..|    |.|| .::.|..|||||.|..||
  Fly   262 TIKTNGTLLCNGCQAIADTGTSLIAVPLAAYRKINRQLGATDNDGE-AFVRCGRVSSLPKVNLNI 325

  Fly   314 GGTNFVLKPSAYIIQSDGN----CMSAFEYM-GTDFWILGDVFIGQYYTEFDLGNNRIGFAPVA 372
            |||.|.|.|..||::...|    |||||.|| |..||||||||||::||.||.||.|||||.||
  Fly   326 GGTVFTLAPRDYIVKVTQNGQTYCMSAFTYMEGLSFWILGDVFIGKFYTVFDKGNERIGFARVA 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bace	NP_001285756.1	pepsin_retropepsin_like	59..369	CDD:299705	192/320 (60%)
		Asp	68..371	CDD:278455	188/313 (60%)
CG17134	NP_609458.1	pepsin_retropepsin_like	70..386	CDD:299705	190/316 (60%)
		Asp	75..388	CDD:278455	188/313 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449704
Domainoid	1	1.000	297	1.000	Domainoid score	I1463
eggNOG	1	0.900	-	-		E1_KOG1339
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	319	1.000	Inparanoid score	I2536
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	1	1.000	-	-		mtm978
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1456
	10	9.900