Protein Alignment Bace and Pgcl

DIOPT Version :9

• Sequence 1: NP_001285756.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_525030.1
• Gene: Pgcl / 30984
• FlyBaseID: FBgn0011822
• Length: 407
• Species: Drosophila melanogaster
• Alignment Length: 369
• Identity: 191/369 - (51%)
• Similarity: 248/369 - (67%)
• Gaps: 3/369 - (0%)

  Fly     5 IAVVVLLAALASAELHRVPILKEQNFVKTRQNVLAEKSYLRTKYQLP-SLRSVDEEQLSNSMNMA 68
            :|.:::|...|::.|.|:||.|..||.::.:|::||:.:::.||... :......|.|||..|..
  Fly    12 LAGLIVLVGEANSTLRRIPIQKSPNFKRSHKNIVAERDFVQQKYNRQYTANGYPMEHLSNYDNFQ 76

  Fly    69 YYGAISIGTPAQSFKVLFDSGSSNLWVPSNTCKSDACLTHNQYDSSASSTYVANGESFSIQYGTG 133
            |||.||||||.|.|.|.||:||||||||.::|.|.||..|..:..:.||||||||.:|||.||||
  Fly    77 YYGNISIGTPGQDFLVQFDTGSSNLWVPGSSCISTACQDHQVFYKNKSSTYVANGTAFSITYGTG 141

  Fly   134 SLTGYLSTDTVDVNGLSIQSQTFAESTNEPGTNFNDANFDGILGMAYESLAVDGVAPPFYNMVSQ 198
            |::||||.|.|...||:||||||.|.|.|.||||.||.|||||||.:.|||||||.|.|.||:.|
  Fly   142 SVSGYLSVDCVGFAGLTIQSQTFGEVTTEQGTNFVDAYFDGILGMGFPSLAVDGVTPTFQNMMQQ 206

  Fly   199 GLVDNSVFSFYLARDGTSTM-GGELIFGGSDASLYSGALTYVPISEQGYWQFTMAGSSIDGYSLC 262
            |||.:.||||:|..:|:.|. |||||.||||.|||||:||||.:.:..||:|......:...|:.
  Fly   207 GLVQSPVFSFFLRDNGSVTFYGGELILGGSDPSLYSGSLTYVNVVQAAYWKFQTDYIKVGSTSIS 271

  Fly   263 DDCQAIADTGTSLIVAPYNAYITLSEILNVGEDGYLDCSSVSSLPDVTFNIGGTNFVLKPSAYII 327
            ...|||||||||||:||...|..:|::.|...:|..:||| :|.||:..||.|.:|.:....|||
  Fly   272 TFAQAIADTGTSLIIAPQAQYDQISQLFNANSEGLFECSS-TSYPDLIININGVDFKIPAKYYII 335

  Fly   328 QSDGNCMSAFEYMGTDFWILGDVFIGQYYTEFDLGNNRIGFAPV 371
            :.:..|..|.:.:..||||:||||:|:.|||||:||.|:|||||
  Fly   336 EEEDFCSLAIQSINQDFWIMGDVFLGRIYTEFDVGNQRLGFAPV 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bace	NP_001285756.1	pepsin_retropepsin_like	59..369	CDD:299705	172/310 (55%)
		Asp	68..371	CDD:278455	169/303 (56%)
Pgcl	NP_525030.1	pepsin_retropepsin_like	67..378	CDD:299705	173/311 (56%)
		Asp	76..379	CDD:278455	169/303 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455536
Domainoid	1	1.000	297	1.000	Domainoid score	I1463
eggNOG	1	0.900	-	-		E1_KOG1339
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	319	1.000	Inparanoid score	I2536
Isobase	1	0.950	-	0	Normalized mean entropy	S1195
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1456
	10	9.850