Protein Alignment Bace and yps1

DIOPT Version :9

• Sequence 1: NP_001285756.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_588035.1
• Gene: yps1 / 2538927
• PomBaseID: SPCC1795.09
• Length: 521
• Species: Schizosaccharomyces pombe
• Alignment Length: 421
• Identity: 96/421 - (22%)
• Similarity: 153/421 - (36%)
• Gaps: 109/421 - (25%)

  Fly    21 RVPILKEQNFVK-------TRQNVLA----EKSYLRTKYQL--------PSLRSVDEEQLSNSMN 66
            |:.||...:|:|       |...|||    .|::...:.||        ||  .:....|.....
pombe     2 RIWILIFFSFIKLVSSLQYTGNGVLALDFVAKTFPNQENQLEKRDYTYSPS--GITSFPLDLQSY 64

  Fly    67 MAYYGAISIGTPAQSFKVLFDSGSSNLW----------------VPSNT-----------CK--S 102
            ..|...:|||.|:.|:.|..|......|                |.|.|           ||  |
pombe    65 TYYTTTLSIGRPSISYTVAIDLDMPYTWLTYYNVMAFNPAYLGIVNSGTQWSTDELRYFLCKKES 129

  Fly   103 DACLTHNQYDSSASSTYVANGESFSIQYGTGSLTGYLSTDTVDVNGLSIQ-SQTFAESTNEPGTN 166
            |:|...|   :|:|..:|.:..:|.|:|          .|.:.|.|:::| |.:::.....|...
pombe   130 DSCYFGN---ASSSFHFVTSPSTFFIRY----------DDNITVAGINVQDSLSYSHYQALPDFQ 181

  Fly   167 F----------NDANFDGILGMAYE--------SLAVDGVAPPFY--NMVSQGLVDNSVFSFYLA 211
            |          :...:.|:||:|..        |.::...:||.:  .:|.:.::....||.||.
pombe   182 FGITLKEYVPSSMLPYKGVLGLAASTEINSIDYSDSISSFSPPTFLEQLVKEDILAYPAFSMYLD 246

  Fly   212 RDGTSTMGGELIFGGSDASLYSG--------ALTYVPISEQGYWQFTMAGSSIDGYSLCDDCQAI 268
            ..|    .|.|:.|..|.|.|.|        .||:..:|.... || :..:....||:..|  |.
pombe   247 NQG----NGSLLLGAVDTSKYQGQFVALKQTKLTHYAVSIYSV-QF-LNSTFFSNYSIITD--AY 303

  Fly   269 ADTGTSLIVAPYNAYITLSEILNVG---EDGY--LDCSSVSSLPDVTFNIGGTNFVLKPSAYII- 327
            ..|..:.|..|  |.:..|.:.|.|   .:||  |:|..:.....:.|..|..:.:..|.:.::
pombe   304 FQTRETYIYLP--AELAYSVMDNAGAYLSEGYFALNCDEIDLEAALIFQFGCNSTIKVPISLLVI 366

  Fly   328 -QSDGNCMSAFEYMGTDFWILGDVFIGQYYT 357
             |....|:...........:||.:|....||
pombe   367 GQVSNICLLGIRPSTDSEIVLGLLFFRNAYT 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bace	NP_001285756.1	pepsin_retropepsin_like	59..369	CDD:299705	82/364 (23%)
		Asp	68..371	CDD:278455	81/355 (23%)
yps1	NP_588035.1	Asp	66..411	CDD:278455	81/355 (23%)
		pepsin_retropepsin_like	150..411	CDD:299705	60/268 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	97	1.000	Domainoid score	I1884
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I1684
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1428
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.980