Protein Alignment Bace and Cym

DIOPT Version :9

• Sequence 1: NP_001285756.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001104613.1
• Gene: Cym / 229697
• MGIID: 2684977
• Length: 379
• Species: Mus musculus
• Alignment Length: 380
• Identity: 151/380 - (39%)
• Similarity: 216/380 - (56%)
• Gaps: 26/380 - (6%)

  Fly     8 VVLLAALASAELH---RVPILKEQNFVKTRQNVLAEKSYL-----RTKYQLPSLRS----VDEEQ 60
            |:||||||.::.|   |:|:.|.    |:.:|.|.|:..|     |.:|:.....|    |..|.
Mouse     5 VLLLAALAISQSHVVTRIPLHKG----KSLRNTLKEQGLLEDFLSRQQYEFSEKNSRIGVVASEP 65

  Fly    61 LSNSMNMAYYGAISIGTPAQSFKVLFDSGSSNLWVPSNTCKSDACLTHNQYDSSASSTYVANGES 125
            |.|.::..|:|.|.||||.|.|.|:||:|||.|||||..|.|..|..|:::|.|.|.|:....:.
Mouse    66 LINYLDSEYFGTIYIGTPPQEFTVVFDTGSSELWVPSVYCNSKVCRNHHRFDPSKSITFQNLSKP 130

  Fly   126 FSIQYGTGSLTGYLSTDTVDVNGLSIQSQTFAESTNEPGTNFNDANFDGILGMAYESLAVDGVAP 190
            ..:|||||.:.|:|:.|||.|:.:.:..||...||.|||..|..:.||||||:||.:.|.....|
Mouse   131 LFVQYGTGRMEGFLAYDTVTVSDIVVSHQTVGLSTQEPGDIFTYSPFDGILGLAYPTFASKYSVP 195

  Fly   191 PFYNMVSQGLVDNSVFSFYLARDGTSTMGGELIFGGSDASLYSGALTYVPISEQGYWQFTMAGSS 255
            .|.||:::.||...:||.|::|   :..|..|..|..|.|.:.|:|.:||::.|||||||:...:
Mouse   196 IFDNMMNRHLVAQDLFSVYMSR---NEQGSMLTLGAIDQSYFIGSLHWVPVTVQGYWQFTVDRIT 257

  Fly   256 IDGYSL-CD-DCQAIADTGTSLIVAPYNAYITLSEILNVGE---DGY-LDCSSVSSLPDVTFNIG 314
            |:|..: |. .|.|:.||||:|:..|....:.:.:::...:   |.: :||..:..:|.|.|.|.
Mouse   258 INGEVVACQGGCPAVLDTGTALLTGPGRDILNIQQVIGAVQGHNDQFDIDCWRLDIMPTVVFEIH 322

  Fly   315 GTNFVLKPSAYIIQSDGNCMSAFEYMGTDFWILGDVFIGQYYTEFDLGNNRIGFA 369
            |..|.|.|.||..|..|.|.|.|: .|:..||||||||.::|:.||..|||:|.|
Mouse   323 GREFPLPPYAYTNQVQGFCSSGFK-QGSHMWILGDVFIREFYSVFDRANNRVGLA 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bace	NP_001285756.1	pepsin_retropepsin_like	59..369	CDD:299705	130/315 (41%)
		Asp	68..371	CDD:278455	128/308 (42%)
Cym	NP_001104613.1	A1_Propeptide	19..44	CDD:285240	8/28 (29%)
		pepsin_retropepsin_like	64..377	CDD:299705	131/317 (41%)
		Asp	73..378	CDD:278455	128/308 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841601
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	1	1.000	-	-		otm43705
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.860