Protein Alignment Bace and asp-15

DIOPT Version :9

• Sequence 1: NP_001285756.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_741675.1
• Gene: asp-15 / 189740
• WormBaseID: WBGene00012681
• Length: 390
• Species: Caenorhabditis elegans
• Alignment Length: 333
• Identity: 116/333 - (34%)
• Similarity: 176/333 - (52%)
• Gaps: 29/333 - (8%)

  Fly    61 LSNSMNMAYYGAISIGTPAQSFKVLFDSGSSNLWVPSNTCKSDAC-------LTHNQYDSSASST 118
            |::.|:..|...|::|||.||..|:..:||:|.||....|.|.||       .|..::.|:.||:
 Worm    57 LADYMDEIYTANITVGTPPQSASVVMGTGSANFWVVGAGCTSPACNGFPDSGHTKLKFYSNKSSS 121

  Fly   119 YVANGESFSIQYGTGSLTGYLSTDTVDVNGLSIQSQTFAESTNEPGTNFNDANFDGILGMAYESL 183
            :|.....|.|.|.||:.:|||.||.:.:.||::::|.||.:| :..........||:||:|:..:
 Worm   122 FVDLNRKFFINYPTGACSGYLGTDVLQLGGLTVKNQEFAVTT-QISDQMGHFPLDGVLGLAWPPV 185

  Fly   184 AVDGVAPPFYNMVSQGLVDNSVFSFYLAR-----DGTSTMGGELIFGGSDASLYSGALTYVPISE 243
            |||.:.||..|::.|  :|..:|:.:|.|     .|.|  ||.:.||..|.......:.||.:|.
 Worm   186 AVDQITPPMQNLMPQ--LDAPIFTLWLDRVLQGSQGGS--GGLITFGAIDTKNCDAQVNYVALSS 246

  Fly   244 QGYWQFTMAGSSIDGYSLCDDCQAIADT---GTSLIVAPYNAYITLSEILN--VGEDGYLDCSSV 303
            :.:|||.:.|.:|..|:.....|||:|:   |..|.:|..||.|..::...  ..|...||||::
 Worm   247 KTFWQFPLDGVAIGSYTSMKKDQAISDSGDFGLRLPLAVLNAVIQQTKATYDWTNEFYTLDCSTM 311

  Fly   304 SSLPDVTFNIGGTNFVLKPSAYIIQ---SDGNCMSA-FEYMGTDF---WILGDVFIGQYYTEFDL 361
            .:.||:.|.|||..:.:|...||:.   .:|.|:.| |....|.|   :..|:||:.||...||:
 Worm   312 QTQPDLVFTIGGMQYPVKSVEYILDLGLGNGRCVLAMFTDSSTGFGPSFGFGNVFLRQYCNIFDV 376

  Fly   362 GNNRIGFA 369
            ||.|||||
 Worm   377 GNARIGFA 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bace	NP_001285756.1	pepsin_retropepsin_like	59..369	CDD:299705	114/331 (34%)
		Asp	68..371	CDD:278455	114/326 (35%)
asp-15	NP_741675.1	Asp	65..384	CDD:365818	112/323 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161976
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.850