Protein Alignment Bace and asp-7

DIOPT Version :9

• Sequence 1: NP_001285756.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_503826.2
• Gene: asp-7 / 186613
• WormBaseID: WBGene00019104
• Length: 380
• Species: Caenorhabditis elegans
• Alignment Length: 387
• Identity: 120/387 - (31%)
• Similarity: 189/387 - (48%)
• Gaps: 35/387 - (9%)

  Fly     4 TIAVVVLLAALASAELHRVPILKEQNFVKTRQNVLAEKSYLRTKYQLPSLRSVDEEQLSNSMNMA 68
            |..:.:|||.|......:..|..|:: |..|:.::.|...|....||    |...|.:.:..:..
 Worm     2 TEKLTILLALLVFCSAGQFSISLEKS-VPLREQLIREGRELARLQQL----STGNESIYDHFDEY 61

  Fly    69 YYGAISIGTPAQSFKVLFDSGSSNLWVPSNTCKSDACLTH--NQYDSSASSTYVANGESFSIQYG 131
            |..::.||||||.|:|..|:.||||||....|||.:|..|  .:|:.:||||::|...:|.:.:.
 Worm    62 YTVSVRIGTPAQHFEVALDTTSSNLWVFGVECKSQSCQGHRIREYNRTASSTFIAGTSNFVLPFN 126

  Fly   132 TGSLTGYLSTDTVDVNGLSIQSQTFAESTNEPGTNFNDANFDGILGMAYESLAVDGVAPPFYNMV 196
            .|.::|.|..|.:...|..||:|.|...|:  .|..:...|||:||:.:.:.|::|.:....|::
 Worm   127 DGDVSGDLGKDNIQFAGSKIQNQDFGIGTD--ATRLSGVTFDGVLGLGWPATALNGTSTTMQNLL 189

  Fly   197 SQGLVDNSVFSFYLARDG--TSTMGGELIFGGSDASLYSGALTYVPISEQGYWQFTMAGSSIDGY 259
            .|  :|..:|:.|..:..  ..|:|||:.||..|.:.....:.||.::....|.:::.|.|...|
 Worm   190 PQ--LDQPLFTTYFTKSSVHNGTVGGEITFGAIDTTHCQSQINYVRLAYDSLWSYSIDGFSFGNY 252

  Fly   260 SLCDDCQAIADTGTSLIVAPYNAYITLSEILNVGEDGY--------LDCSSVSSLPDVTFNIGGT 316
            |......||.||.:|....|   .:.|:||:......|        |.|||.::|||:.|.|||.
 Worm   253 SRNQTDTAIPDTTSSYTGVP---NLVLAEIVIATGAQYDWNHQAYTLPCSSTATLPDLVFTIGGN 314

  Fly   317 NFVLKPSAYIIQ---SDGNCMSAFEYMGT------DFWILGDVFIGQYYTEFDLGNNRIGFA 369
            ::.::...|::.   .:|.|  |....||      ..|:.||.|:..|...||.||:|||.|
 Worm   315 SYNVRAVEYVVNLNLPNGQC--ALSLFGTFSSPSGPLWVFGDNFLRSYCHIFDFGNSRIGLA 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bace	NP_001285756.1	pepsin_retropepsin_like	59..369	CDD:299705	105/330 (32%)
		Asp	68..371	CDD:278455	105/323 (33%)
asp-7	NP_503826.2	Asp	60..376	CDD:365818	105/324 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161973
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.750