Protein Alignment Bace and hrg-7

DIOPT Version :9

• Sequence 1: NP_001285756.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001256448.1
• Gene: hrg-7 / 182635
• WormBaseID: WBGene00007605
• Length: 428
• Species: Caenorhabditis elegans
• Alignment Length: 435
• Identity: 139/435 - (31%)
• Similarity: 214/435 - (49%)
• Gaps: 75/435 - (17%)

  Fly     3 KTIAVVVLLAALASAELHRVPILKEQNFVKTRQNV---LAEKSYLRTKYQLPSLRSVDEEQLSNS 64
            ||...::.|..:.|||:|:..|....| ::.|.|.   |||  |.:.:.:|.|.:|:   ||::|
 Worm     2 KTFIALLALLTVVSAEVHQFNIGYRPN-MRQRMNAKGKLAE--YEKERNELLSKKSL---QLASS 60

  Fly    65 M-------NMAYYGAISIGTPAQSFKVLFDSGSSNLWVPSNTC---------------------- 100
            .       :|||...||:|:|||:|.:..||||||||||..||
 Worm    61 SSPVIDYEDMAYMVQISLGSPAQNFVLFIDSGSSNLWVPDITCAGGKDATCGSYCKSTPYDACLT 125

  Fly   101 ------------------KSDACLTHNQYDSSASSTYVANGESFSIQYGTGSLTGYLSTDTVDVN 147
                              .:|||.:.::::||.||:||.||:.|.:.|.||.:.|:...||....
 Worm   126 FCQEECCTKTVEGVKVLSTTDACQSKHRFNSSLSSSYVTNGQKFDMTYNTGEVKGFFGVDTFCFT 190

  Fly   148 GLSI--QSQTFAESTNEPGTNFNDANFDGILGMAYESLAVDGVAPPFYNMVSQGLVDNSVFSFYL 210
            ..|:  ..|.|.::|. .|..|.....|||:|:.:.:|||:...||.:|:::||.:|...|..||
 Worm   191 NTSVCATGQVFGQATT-IGEAFAKQPEDGIIGLGWPALAVNQQTPPLFNLMNQGKLDQPYFVVYL 254

  Fly   211 ARDGTSTM--GGELIFGGSDASLYSGALTYVPISEQGYWQFTMAGSSIDGYSLCDDC--QAIADT 271
            |..|.::.  ||....||.|.:..|..:.:||:|.|.:|||.:.|.|...||...:.  ||.|||
 Worm   255 ANIGPTSQINGGAFTVGGLDTTHCSSNVDWVPLSTQTFWQFKLGGVSSGSYSQAPNSGWQAAADT 319

  Fly   272 GTSLIVAPYNAYITLSEILN---VGEDG--YLDCSSVSSLPDVTFNIGGTNFVLKPSAYIIQS-D 330
            ..|.|.||.:...:|::.:.   |...|  ::||.:|  :||:.|.|.|..:.:..:::::.: .
 Worm   320 AASFIGAPKSVVTSLAKAVGATYVPLTGAFFMDCDAV--VPDIVFTINGKTYNMPSTSFVVSAGP 382

  Fly   331 GNCMSAF-EYMGTDF---WILGDVFIGQYYTEFDLGNNRIGFAPV 371
            |.||.|| |.....|   |:||..|:..|....|:.:.|:|.|.|
 Worm   383 GPCMFAFYELTAGGFYPAWMLGPPFMRAYCHVHDMKSGRLGLAKV 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bace	NP_001285756.1	pepsin_retropepsin_like	59..369	CDD:299705	119/372 (32%)
		Asp	68..371	CDD:278455	116/358 (32%)
hrg-7	NP_001256448.1	pepsin_retropepsin_like	71..427	CDD:416259	116/358 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020